Patient-individualized efficacy rating

• US 8,306,624 B2
• Filed: 04/28/2006
• Issued: 11/06/2012
• Est. Priority Date: 04/28/2006
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Gerber, Martin T., Rondoni, John C.
• Primary Examiner(s): Lavert, Nicole F
• Application Number:
  US11/414,616
• Publication Number:
  US 20070255322A1
• Time in Patent Office: 2,384 Days
• Field of Search: 607/7, 607/41, 607/46, 607/63
• US Class Current: 607/41
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

The disclosure is directed to techniques for providing a patient-individualized efficacy rating. Different stimulation parameters impact efficacy. For example, efficacy may be a function of parameters such as electrode combination, stimulation amplitude, pulse width, and pulse rate. Efficacy may vary from patient-to-patient. For example, efficacy may vary according to age, gender, physiology, disease state, activity level, or activity profile. Comparable stimulation programs may provide different efficacy levels for different patients, according to patient characteristics or desires. Patients may rank efficacy parameters differently. The efficacy parameters may include desirable therapeutic effects and undesirable side effects. For one patient, optimization of a particular efficacy parameter may be the paramount concern. Other patients may be willing to compromise the outcome of the same parameter in favor of better outcomes with other efficacy parameters. A patient-individualized efficacy rating permits a patient and clinician to customize efficacy evaluation according to the patient'"'"'s condition or needs.

Claims

1. A method comprising:

receiving input, in at least one graphical user interface of at least one device, specifying one or more efficacy parameters from a set of selectable efficacy parameters associated with therapy delivered to a patient;

receiving input, in the at least one graphical user interface of the at least one device, specifying, for the efficacy parameters, one or more patient-individualized weighting values and one or more clinician weighting values, wherein at least one of the patient-individualized weighting values and at least one of the clinician weighting values is specified for each of the efficacy parameters;

receiving input, in the at least one graphical user interface of the at least one device, specifying one or more efficacy parameter values associated with the efficacy parameters, wherein at least one of the efficacy parameter values is specified for each of the efficacy parameters;

receiving, by at least one processor of the at least one device, the patient-individualized weighting values, the clinician weighting values, and the efficacy parameter values from the at least one graphical user interface;

determining, by the at least one processor of the at least one device, patient-individualized weighted efficacy parameter values based on application of the patient-individualized weighting values to the efficacy parameter values;

determining, by the at least one processor of the at least one device, clinician weighted efficacy parameter values based on application of the clinician weighting values to the efficacy parameter values;

calculating a patient-individualized portion of a patient-individualized efficacy rating based upon the patient-individualized weighted efficacy parameter values;

calculating a clinician portion of the patient-individualized efficacy rating based upon the clinician weighted efficacy parameter values; and

graphically displaying, in the at least one graphical user interface, independent representations of each of the patient portion and the clinician portion of the patient-individualized efficacy rating for the therapy delivered to the patient.

2. The method of claim 1, wherein the therapy includes electrical stimulation therapy.

3. The method of claim 1, wherein the efficacy parameters include parameters relating to therapeutic relief.

4. The method of claim 3, wherein the efficacy parameters include parameters relating to undesirable side effects.

5. The method of claim 1, wherein the efficacy parameters include quality of life (QOL) survey information obtained from the patient.

6. The method of claim 1, wherein the therapy includes electrical stimulation therapy configured to relieve incontinence, and the efficacy parameters include one or more of incontinent episodes, urination frequency, and nocturia.

7. The method of claim 1, wherein receiving input specifying the efficacy parameter values comprises receiving patient input specifying the efficacy parameter values associated with the efficacy parameters, the method further comprising summing the patient-individualized weighted efficacy parameter values to produce the patient-individualized portion of the patient-individualized efficacy rating.

8. The method of claim 1, wherein receiving input specifying the efficacy parameter values comprises receiving both patient and clinician input specifying the efficacy parameter values associated with the efficacy parameters, the method further comprising summing the patient-individualized weighted efficacy parameter values to produce the patient-individualized portion of the patient-individualized efficacy rating.

9. The method of claim 1, further comprising receiving the one or more patient-individualized weighting values via a patient programmer and receiving the one or more clinician weighting values via a clinician programmer.

10. The method of claim 1, wherein receiving input specifying one or more efficacy parameters associated with therapy includes receiving input specifying a patient-individualized subset of the efficacy parameters, the method further comprising receiving input specifying the patient-individualized weighting values for the patient-individualized subset of the efficacy parameters.

11. The method of claim 1, further comprising:

receiving patient input specifying the efficacy parameter values associated with the efficacy parameters;

summing the patient-individualized weighted efficacy parameter values to produce the patient-individualized portion of the patient-individualized efficacy rating.

12. The method of claim 1, further comprising:

establishing one or more baseline efficacy values for the efficacy parameters prior to delivery of the therapy to the patient,

wherein receiving input specifying the efficacy parameter values comprises receiving input, in the at least one graphical user interface, specifying the efficacy parameter values upon delivery of the therapy to the patient, and

wherein graphically displaying independent representations of each of the patient portion and the clinician portion of the patient-individualized efficacy rating further includes graphically displaying, in the at least one graphical user interface, a representation of each of the baseline efficacy values in conjunction with each of the patient-individualized weighted efficacy parameter values and each of the clinician weighted efficacy parameter values.

13. A device comprising:

a graphical user interface of the device that;

receives input specifying one or more efficacy parameters from a set of selectable efficacy parameters associated with therapy delivered to a patient,

receives input specifying, for the efficacy parameters, one or more patient-individualized weighting values and one or more clinician weighting values, and

receives input specifying one or more efficacy parameter values associated with the efficacy parameters, wherein at least one of the patient-individualized weighting values and at least one of the clinician weighting values is specified for each of the efficacy parameters, and wherein at least one of the efficacy parameter values is specified for each of the efficacy parameters; and

at least one processor that;

receives, from the graphical user interface, the patient-individualized weighting values, the clinician weighting values, and the efficacy parameter values,

determines patient-individualized weighted efficacy parameter values based on application of the patient-individualized weighting values to the efficacy parameter values,

determine clinician weighted efficacy parameter values based on application of the clinician weighting values to the efficacy parameter values,

calculates a patient-individualized portion of a patient-individualized efficacy rating based upon the patient-individualized weighted efficacy parameter values, and

calculates a clinician portion of the patient-individualized efficacy rating based upon the clinician weighted efficacy parameter values,

such that independent representations of each of the patient portion and the clinician portion of the patient-individualized efficacy rating for the therapy delivered to the patient are displayable in the graphical user interface.

14. The device of claim 13, wherein the therapy includes electrical stimulation therapy.

15. The device of claim 13, wherein the efficacy parameters include parameters relating to therapeutic relief.

16. The device of claim 13, wherein the efficacy parameters include parameters relating to undesirable side effects.

17. The device of claim 13, wherein the efficacy parameters include quality of life (QOL) survey information obtained from the patient.

18. The device of claim 13, wherein the therapy includes electrical stimulation therapy, and wherein the electrical stimulation therapy is configured to relieve incontinence, and the efficacy parameters include one or more of incontinent episodes, urination frequency, and nocturia.

19. The device of claim 13, wherein the graphical user interface receives patient input specifying the efficacy parameter values associated with the efficacy parameters, and wherein the processor sums the patient-individualized weighted efficacy parameter values to produce the patient-individualized portion of the patient-individualized efficacy rating.

20. The device of claim 13, wherein the graphical user interface receives the one or more patient-individualized weighting values and the one or more clinician weighting values associated with the efficacy parameters, and wherein the processor sums the patient-individualized weighted efficacy parameter values to produce the patient-individualized portion of the patient-individualized efficacy rating.

21. The device of claim 13, wherein the graphical user interface receives input specifying a patient-individualized subset of the efficacy parameters, and input specifying the patient-individualized weighting values for the patient-individualized subset of the efficacy parameters.

22. The device of claim 13, wherein the graphical user interface receives patient input specifying efficacy parameter values associated with the efficacy parameters, wherein the processor sums the patient-individualized weighted efficacy parameter values to produce an overall efficacy rating.

23. The device of claim 13, wherein:

the processor establishes one or more baseline efficacy values for the efficacy parameters prior to delivery of the therapy to the patient;

the graphical user interface receives input specifying the efficacy parameter values at least by receiving input specifying the efficacy parameter values upon delivery of the therapy to the patient; and

the graphical user interface displays a representation of each of the baseline efficacy values in conjunction with each of the patient-individualized weighted efficacy parameter values and each of the clinician weighted parameter values.

24. A computer-readable storage medium comprising instructions to cause at least one processor to:

receive input, in at least one graphical user interface, specifying one or more efficacy parameters from a set of selectable efficacy parameters associated with therapy delivered to a patient;

receive input, in the at least one graphical user interface, specifying, for the efficacy parameters, one or more patient-individualized weighting values and one or more clinician weighting values, wherein at least one of the patient-individualized weighting values and at least one of the clinician weighting values is specified for each of the efficacy parameters;

receive input, in the at least one graphical user interface, specifying one or more efficacy parameter values associated with the efficacy parameters wherein at least one of the efficacy parameter values is specified for each of the efficacy parameters;

receive the patient-individualized weighting values, the clinician weighting values, and the efficacy parameter values from the at least one graphical user interface;

determine patient-individualized weighted efficacy parameter values based on application of the patient-individualized weighting values to the efficacy parameter values;

determine clinician weighted efficacy parameter values based on application of the clinician weighting values to the efficacy parameter values;

calculate a patient-individualized portion of a patient-individualized efficacy rating based upon the patient-individualized weighted efficacy parameter values;

calculate a clinician portion of the patient-individualized efficacy rating based upon the clinician weighted efficacy parameter values; and

graphically display, in the at least one graphical user interface, independent representations of each of the patient portion and the clinician portion of the patient-individualized efficacy rating for the therapy delivered to the patient.

25. The computer-readable medium of claim 24, wherein the therapy includes electrical stimulation therapy.

26. The computer-readable medium of claim 24, wherein the efficacy parameters include parameters relating to therapeutic relief and parameters relating to undesirable side effects.

27. The computer-readable medium of claim 24, wherein the therapy includes electrical stimulation therapy, and wherein the electrical stimulation therapy is configured to relieve incontinence, and the efficacy parameters include one or more of incontinent episodes, urination frequency, and nocturia.

28. The computer-readable medium of claim 24, wherein the efficacy parameters include a patient-individualized subset of the efficacy parameters, and the instructions cause the at least one processor to receive input specifying the patient-individualized weighting values for the patient-individualized subset of the efficacy parameters.

29. The computer-readable storage medium of claim 24,

wherein the instructions further cause the at least one processor to establish one or more baseline efficacy values for the efficacy parameters prior to delivery of the therapy to the patient,

wherein the instructions cause the at least one processor to receive input, in the at least one graphical user interface, specifying the efficacy parameter values upon delivery of the therapy to the patient, and

wherein the instructions cause the at least one processor to graphically display, in the at least one graphical user interface, a representation of each of the baseline efficacy values in conjunction with each of the patient-individualized weighted efficacy parameter values and each of the clinician weighted efficacy parameter values.

30. A device comprising:

means for specifying one or more efficacy parameters from a set of selectable efficacy parameters associated with therapy delivered to a patient from input received in at least one graphical user interface; and

means for specifying, for the efficacy parameters, one or more patient-individualized weighting values and one or more clinician weighting values from input received in the at least one graphical user interface, wherein at least one of the patient-individualized weighting values and at least one of the clinician weighting values is specified for each of the efficacy parameters;

means for specifying one or more efficacy parameter values associated with the efficacy parameters from input received in the at least one graphical user interface, wherein at least one of the efficacy parameter values is specified for each of the efficacy parameters;

means for receiving the patient-individualized weighting values, the clinician weighting values, and the efficacy parameter values from the at least one graphical user interface; and

means for determining patient-individualized weighted efficacy parameter values based on application of the patient-individualized weighting values to the efficacy parameter values;

means for determining clinician weighted efficacy parameter values based on application of the clinician weighting values to the efficacy parameter values;

means for calculating a patient-individualized portion of a patient-individualized efficacy rating based upon the patient-individualized weighted efficacy parameter values;

means for calculating a clinician portion of the patient-individualized efficacy rating based upon the clinician weighted efficacy parameter values; and

means for graphically displaying independent representations of each of the patient portion and the clinician portion of the patient-individualized efficacy rating for the therapy delivered to the patient.

31. The device of claim 30, wherein the therapy includes electrical stimulation therapy.

32. The device of claim 30, wherein the device comprises an external programmer for an implantable medical device.

33. The device of claim 30, wherein the device comprises an external programmer for an implantable medical device.

34. The device of claim 30, further comprising:

means for establishing one or more baseline efficacy values for the efficacy parameters prior to delivery of the therapy to the patient,

wherein the means for receiving input specifying the efficacy parameter values comprises means for receiving input specifying the efficacy parameter values upon delivery of the therapy to the patient, and

wherein the means for graphically displaying a representation of each of the patient-individualized weighted efficacy parameter values comprises means for graphically displaying a representation of each of the baseline efficacy values in conjunction with each of the patient-individualized weighted efficacy parameter values and each of the clinician weighted efficacy parameter values.