Apparatus, method and system for determining a physiological condition within a mammal
First Claim
1. An apparatus for measuring a physiological condition within a mammal comprising:
- an elongated tubular housing extending along a longitudinal axis from a distal end to a proximal end, the elongated tubular housing having an internal cavity;
a first opening in the elongated tubular housing funning a first passageway into the internal cavity;
an ion-sensitive field effect transistor (ISFET) for measuring pH within a body lumen of the mammal, the ISFET positioned in the internal cavity, the ISFET aligned with the first opening, so that at least a portion of the ISFET is exposed via the first opening;
a first seal between the ISFET and the elongated tubular housing forming a hermetic seal about a perimeter of the first opening;
a temperature sensor for measuring temperature within the body lumen;
a second opening in the elongated tubular housing forming a second passageway into the internal cavity;
the temperature sensor comprising a thermistor covered by a metal cap, the metal cap exposed via the second opening; and
a second seal between the metal cap and the elongated tubular housing forming a hermetic seal about a perimeter of the second opening.
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Accused Products
Abstract
A system, method and apparatus for determining a physiological condition within a mammal based on pH and/or temperature measurements. In one aspect, the invention is directed to an apparatus for measuring a physiological condition within a mammal comprising: a tubular housing extending along a longitudinal axis from a distal end to a proximal end, the housing having an internal cavity; a first opening in the elongated housing forming a first passageway into the internal cavity; an ion-sensitive field effect transistor (ISFET) for measuring pH within a body lumen of the mammal, the ISFET positioned in the internal cavity, the ISFET aligned with the first opening so that at least a portion of the ISFET is exposed via the first opening; and a first seal between the ISFET and the housing forming a hermetic seal about a perimeter of the first opening.
36 Citations
9 Claims
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1. An apparatus for measuring a physiological condition within a mammal comprising:
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an elongated tubular housing extending along a longitudinal axis from a distal end to a proximal end, the elongated tubular housing having an internal cavity; a first opening in the elongated tubular housing funning a first passageway into the internal cavity; an ion-sensitive field effect transistor (ISFET) for measuring pH within a body lumen of the mammal, the ISFET positioned in the internal cavity, the ISFET aligned with the first opening, so that at least a portion of the ISFET is exposed via the first opening; a first seal between the ISFET and the elongated tubular housing forming a hermetic seal about a perimeter of the first opening; a temperature sensor for measuring temperature within the body lumen; a second opening in the elongated tubular housing forming a second passageway into the internal cavity; the temperature sensor comprising a thermistor covered by a metal cap, the metal cap exposed via the second opening; and a second seal between the metal cap and the elongated tubular housing forming a hermetic seal about a perimeter of the second opening. - View Dependent Claims (2, 3, 4, 5, 6)
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7. An apparatus for measuring a physiological condition within a mammal comprising:
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an elongated tubular housing extending along a longitudinal axis from a distal end to a proximal end; and an ion-sensitive field effect transistor (ISFET) for measuring pH within a body lumen of the mammal, the ISFET located on a distal portion of the elongated tubular housing and having at least a portion of the ISFET exposed for contact with fluid of the body lumen; a memory device located within the elongated tubular housing, the memory device storing parametric data unique to the pH sensor; and wherein the parametric data includes first ISFET slope data determined at ambient temperature and second ISFET slope data determined at normal body temperature. - View Dependent Claims (8)
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9. An apparatus for measuring a physiological condition within a mammal comprising:
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an elongated tubular housing extending along a longitudinal axis from a distal end to a proximal end; an ion-sensitive field effect transistor (ISFET) for measuring pH within a body lumen of the mammal, the ISFET located on a distal portion of the housing and having at least a portion of the ISFET exposed; a temperature sensor for measuring temperature within the body lumen, the temperature sensor located on a distal portion of the housing and having at least a portion of the temperature sensor exposed; a memory device storing parametric data unique to the pH sensor, the parametric data includes first ISFET slope data determined at ambient temperature and second ISFET slope data determined at normal body temperature; a first interface connector operably coupled to the ISFET, the temperature sensor and the memory device, the first interface connector located at the proximal end of the housing; and a first circuit board located within the housing, the ISFET, the temperature sensor, the memory device and the first interface connector operably coupled to the first circuit hoard.
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Specification