Bio-sensing device capable of automatically detecting sensing code and sensing method thereof
First Claim
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1. A bio-sensing device capable of automatically detecting a sensing code, the bio-sensing device comprising:
- a bio-sensing strip comprising;
a first electrode being electrically connectible to an electronic circuit and having enzyme contained thereon to react with a sample;
a second electrode being electrically connectible to the electronic circuit and having the enzyme contained thereon to react with the sample;
a capacitor having an end thereof connected to the first electrode and having a capacitance value that is able to represent a sensing code of the bio-sensing strip; and
a third electrode being connected to the other end of the capacitor, so that the capacitor is able to be electrically connected to the electronic circuit; and
a process-and-display unit being configured to quantitate an electrochemical reaction signal representing an electrochemical reaction of the sample with the enzyme contained reagent matrix, the process-and-display unit comprising;
a detection circuit being electrically connectible to the bio-sensing strip to detect the physical value of the capacitor and configured to convert the physical value into a first digital signal;
a read circuit being electrically connectible to the bio-sensing strip to read the electrochemical reaction signal representing the electrochemical reaction of the sample with the enzyme contained reagent matrix and configured to convert the electrochemical reaction signal into a second digital signal;
a microprocessor being electrically connected to the detection circuit and the read circuit and configured to verify the sensing code of the bio-sensing strip by processing the first digital signal and further set an appropriate compensation value, configured to receive the second digital signal and process the second digital signal into a sample measurement value, and configured to numerically compensate the sample measurement value based on the appropriate compensation value to output an accurate sample magnitude value; and
a display member being electrically connected to the microprocessor to display the accurate sample magnitude value;
wherein the detection circuit having;
a current source being adapted to charge the capacitor to generate a charging voltage;
a comparator comprising a comparator positive input terminal, a comparator negative input terminal and a comparator output terminal, where the comparator negative input terminal is coupled to a reference voltage and the comparator positive input terminal is coupled to the capacitor;
therefore the comparator is configured to compare the charging voltage of the capacitor with the reference voltage, and then outputs a high-level signal when the charging voltage value is higher than that of the reference voltage; and
a counter being coupled to the microprocessor, the comparator and an activation signal, wherein when the activation signal is set to a high level, the current source charging the capacitor and, meanwhile, the counter starting to count until the comparator outputs the high-level signal to the counter, and then the counter stops counting and records a count value.
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Abstract
The present invention relates to a bio-sensing device capable of automatically detecting a sensing code and a sensing method thereof. The bio-sensing device has a bio-sensing strip and a process-and-display unit. The bio-sensing strip has a passive component, wherein a physical value of the passive component is able to present a sensing code. When the bio-sensing strip is inserted into the process-and-display unit, the process-and-display unit reads the sensing code to produce an appropriate compensation value of a sample. Moreover, by the sensing method, the process-and-display unit is able to detect the sensing code of the bio-sensing strip, and automatically, to access, calculate, compensate, and display the sensing code of the sample.
9 Citations
7 Claims
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1. A bio-sensing device capable of automatically detecting a sensing code, the bio-sensing device comprising:
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a bio-sensing strip comprising; a first electrode being electrically connectible to an electronic circuit and having enzyme contained thereon to react with a sample; a second electrode being electrically connectible to the electronic circuit and having the enzyme contained thereon to react with the sample; a capacitor having an end thereof connected to the first electrode and having a capacitance value that is able to represent a sensing code of the bio-sensing strip; and a third electrode being connected to the other end of the capacitor, so that the capacitor is able to be electrically connected to the electronic circuit; and a process-and-display unit being configured to quantitate an electrochemical reaction signal representing an electrochemical reaction of the sample with the enzyme contained reagent matrix, the process-and-display unit comprising; a detection circuit being electrically connectible to the bio-sensing strip to detect the physical value of the capacitor and configured to convert the physical value into a first digital signal; a read circuit being electrically connectible to the bio-sensing strip to read the electrochemical reaction signal representing the electrochemical reaction of the sample with the enzyme contained reagent matrix and configured to convert the electrochemical reaction signal into a second digital signal; a microprocessor being electrically connected to the detection circuit and the read circuit and configured to verify the sensing code of the bio-sensing strip by processing the first digital signal and further set an appropriate compensation value, configured to receive the second digital signal and process the second digital signal into a sample measurement value, and configured to numerically compensate the sample measurement value based on the appropriate compensation value to output an accurate sample magnitude value; and a display member being electrically connected to the microprocessor to display the accurate sample magnitude value; wherein the detection circuit having; a current source being adapted to charge the capacitor to generate a charging voltage; a comparator comprising a comparator positive input terminal, a comparator negative input terminal and a comparator output terminal, where the comparator negative input terminal is coupled to a reference voltage and the comparator positive input terminal is coupled to the capacitor;
therefore the comparator is configured to compare the charging voltage of the capacitor with the reference voltage, and then outputs a high-level signal when the charging voltage value is higher than that of the reference voltage; anda counter being coupled to the microprocessor, the comparator and an activation signal, wherein when the activation signal is set to a high level, the current source charging the capacitor and, meanwhile, the counter starting to count until the comparator outputs the high-level signal to the counter, and then the counter stops counting and records a count value. - View Dependent Claims (2, 3, 4, 5)
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6. A sensing method for a bio-sensing device, comprising:
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(1) inserting a bio-sensing strip having a capacitor into a process-and-display unit of the bio-sensing device; (2) enabling the process-and-display unit to activate a detection circuit thereon; (3) enabling the detection circuit to detect a physical value of the capacitor and convert the physical value into a first digital signal; (31) setting an activation signal to a high level to activate a current source and a counter; (32) enabling the current source to charge the capacitor to generate a charging voltage; (33) enabling a comparator to receive the charging voltage and a reference voltage simultaneously; (34) enabling the comparator to determine whether the charging voltage is higher than the reference voltage, if yes, the step (35) will be executed and if not, the step (33) will be executed; (35) enabling the comparator to output a high-level signal to the counter; (36) enabling the counter to stop counting and record a count value; (4) enabling a microprocessor to receive the first digital signal to verify a sensing code of the bio-sensing strip; (5) enabling the microprocessor to further set an appropriate compensation value according to the sensing code; (6) dripping a sample onto enzyme contained reagent matrix of the bio-sensing strip; (7) enabling the process-and-display unit to activate a read circuit thereon; (8) enabling the read circuit to read an electrochemical reaction signal representing an electrochemical reaction of the sample with the enzyme contained reagent matrix and convert the electrochemical reaction signal into a second digital signal; (9) enabling the microprocessor to receive the second digital signal and process the second digital signal into a sample measurement value; and (10) enabling the microprocessor to numerically compensate the sample measurement value based on the appropriate compensation value to obtain and output an accurate sample magnitude value. - View Dependent Claims (7)
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Specification
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Current AssigneeR3dstar Biomedical Corporation
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Original AssigneeR3dstar Biomedical Corporation
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InventorsChen, Chun-Yu, Hsiao, Chung-Chih, Tang, Chung-Ping
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Primary Examiner(s)Olsen, Kaj K
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Application NumberUS12/693,419Publication NumberTime in Patent Office1,023 DaysField of Search204/403.01, 204/403.02, 204/403.04, 204/406, 205/777.5, 205/792US Class Current205/777.5CPC Class CodesA61B 2562/085 combined with means for rec...A61B 5/14532 for measuring glucose, e.g....A61B 5/1468 using chemical or electroch...
