High alcohol content foaming compositions with silicone-based surfactants

• US 8,309,111 B2
• Filed: 09/14/2006
• Issued: 11/13/2012
• Est. Priority Date: 03/07/2005
• Status: Active Grant

• Current Assignee: DEB IP Limited (SC Johnson & Son Incorporated)
• Original Assignee: DEB Worldwide Healthcare Incorporated
• Inventors: Fernandez de Castro, Maria Teresa, Koivisto, Bruce Michael, Munoz, Francisco
• Primary Examiner(s): Haghighatian, Mina
• Assistant Examiner(s): Chui, Helen
• Application Number:
  US11/520,819
• Publication Number:
  US 20070065383A1
• Time in Patent Office: 2,252 Days
• Field of Search: 424/405, 424/1.657, 424/78.07
• US Class Current: 424/405
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/06 Aerosols
• CPC Class Codes: A01N 25/16 Foams
• CPC Class Codes: A01N 25/30 characterised by the surfactants
• CPC Class Codes: A01N 31/02 Acyclic compounds
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/894 modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 31/00 Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• CPC Class Codes: A61P 31/02 Local antiseptics
• CPC Class Codes: A61Q 17/005 Antimicrobial preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: B65D 83/00 Containers or packages with special means for dispensing contents dispensing means incorporated in removable or non-permanently secured container closures B65D47/00; for shops, stores, offices, bars, or the like A47F1/04; showcases or show cabinets with dispensing arrangements A47F3/02; magazines for screws or nuts in combination with spanners, wrenches or screwdrivers B25B23/06; for use in connection with the handling of sheets, webs, or filamentary material B65H
• CPC Class Codes: C08J 2373/00 Characterised by the use of macromolecular compounds obtained by reactions forming a linkage containing oxygen or oxygen and carbon in the main chain, not provided for in groups C08J2359/00 - C08J2371/00; Derivatives of such polymers
• CPC Class Codes: C08J 9/0023 containing oxygen
• CPC Class Codes: C08J 9/0042 containing silicon
• CPC Class Codes: C08J 9/125 Water, e.g. hydrated salts
• CPC Class Codes: C11D 1/82 Compounds containing silicon
• CPC Class Codes: C11D 3/0094 : High foaming compositions
• CPC Class Codes: C11D 3/201 : linear
• CPC Class Codes: C11D 3/2013 : fatty or with at least 8 carbon atoms in the alkyl chain

Abstract

This invention relates to a “high lower alcohol content” (>40% v/v of a C_1-4 alcohol) liquid composition able to be dispensed as a stable foam with the use of non-propellant foam dispensing devices from non-pressurized containers. The liquid compositions comprise a C_1-4 alcohol, (>40% v/v), a silicone-based surfactant of at least 0.001% by weight for foaming to prepare a foamable composition, 0-10% w/w of additional minor components added to obtain the desired performance (a foamable composition), and the balance being purified water. The compositions may include emulsifier-emollients and mosturizers, secondary surfactants, foam stabilizers, fragrances, antimicrobial agents, other type of medicinal ingredients, and the like ingredients or additives or combinations thereof commonly added to alcohol gels or foams, aerosol compositions or to toiletries, cosmetics, pharmaceuticals and the like.

Claims

1. An unpressurized dispenser having a dispenser pump for mixing a composition with air and dispensing foam, the dispenser storing a foamable composition comprising:

a) a C_1-4 alcohol, or a mixture thereof, present in an amount greater than 60% v/v of the total composition;

b) an effective physiologically acceptable silicone-based surface active agent for foaming, present in an amount of at least 0.01% by weight of the total composition; and

c) water present in an amount to balance the total composition to 100% by weight, wherein the composition is mixed with air at low pressure to form a foam.

2. The unpressurized dispenser according to claim 1 wherein the alcohol is ethanol present in an amount of at least 60% v/v.

3. The unpressurized dispenser according to claim 1 wherein the alcohol is a mixture of n-propanol and ethanol present in a combined amount of at least 60% v/v.

4. The unpressurized dispenser according to claim 1 wherein the alcohol is a mixture of isopropanol and ethanol present in a combined amount of at least 60% v/v.

5. The unpressurized dispenser according to claim 1 wherein the alcohol is isopropanol present in an amount of at least 70% v/v.

6. The unpressurized dispenser according to claim 1 wherein alcohol is n-propanol present in an amount of at least 60% v/v.

7. The unpressurized dispenser according to claim 1 further including at least one additional surfactant present in an amount no more than 1% by weight for adjusting properties of foam produced from the composition.

8. The unpressurized dispenser according to claim 7 wherein the additional surfactant is selected from the group consisting of alkylglucosides, poly(ethoxylated and/or propoxylated)alcohol, a poly(ethoxylated and/or propoxylated)ester, an alkyl alcohol, an alkenyl alcohol, an ester of a polyhydric alcohol, an ether of a polyhydric alcohol, an ester of a polyalkoxylated polyhydric alcohol, an ether of a polyalkoxylated polyhydric alcohol, a sorbitan fatty acid ester, a polyalkoxylated sorbitan fatty acid ester, a betaine, a sulfobetaine, an imidazoline, an amino acid, a lecithin, a phosphatide, an amine oxide, a sulfoxide and mixtures thereof.

9. The unpressurized dispenser according to claim 8 wherein the betaine is cocamidopropyl betaine.

10. The unpressurized dispenser according to claim 1 further including one or more moisturizers, emollients, lipid layer enhancers, or combinations thereof selected from the group consisting of

lanolin,

vinyl alcohol,

polyvinyl pyrrolidone,

polyols selected from the group consisting of glycerol, propylene glycol, butyleneglycol, glyceryl oleate and sorbitol,

cocoglucoside,

a fatty alcohol selected from the group consisting of cetyl alcohol, stearyl alcohol, lauryl alcohol, myristyl alcohol and palmityl alcohol,

ceteareth 20,

an alkylglucoside,

mixtures of alkylglucoside and glyceryl oleate,

PEG-200 hydrogenated glyceryl palmate,

dihydroxypropyl PEG-5 linoleammonium chloride,

PEG-7 glyceryl cocoate,

and combinations thereof, present in an amount up to about 5% by weight of the total composition.

11. The unpressurized dispenser according to claim 1 further comprising an acid or a base to adjust a pH of the composition to a pre-selected pH, present in an amount from about 0.05 to about 0.5% by weight of the total composition.

12. The unpressurized dispenser according to claim 1 further including a preservative in an amount from about 0.01 to about 5% by weight of the total composition.

13. The unpressurized dispenser according to claim 1 further including an antimicrobial agent.

14. The unpressurized dispenser according to claim 13 wherein the antimicrobial agent is benzalkonium chloride present in an amount from about 0.05% to about 5.0% by weight of the total composition.

15. The unpressurized dispenser according to claim 1 further comprising one or more constituents selected from the group consisting of organic gums and colloids, lower alkanolamides of higher fatty acids, short chain diols, triols, fragrance, coloring matter, ultraviolet absorbers, solvents, buffers, conditioning agents, antioxidants, bactericides and medicinally active ingredients, and combinations thereof.

16. A method of forming a foam using the unpressurized dispenser of claim 1, the method comprising activating the dispenser pump to mix the alcohol and silicone-based surface active agent mixture with air under low pressure conditions to form an alcohol foam which is dispensed from said container.

23. The unpressurized dispenser according to claim 1 wherein the foamable composition further comprises a fragrance.

24. The unpressurized dispenser according to claim 1, wherein the foamable composition further comprises glycerol and propylene glycol.

25. The unpressurized dispenser according to claim 1, wherein the foamable composition further comprises a foam stabilizer.

26. The unpressurized dispenser according to claim 1, wherein the foamable composition comprises ethanol and isopropanol.

27. The unpressurized dispenser according to claim 1, wherein the foamable alcohol composition further comprises PEG-7 glyceryl cocoate.

28. The unpressurized dispenser of claim 25, wherein the foam stabilizer is glycerine.

29. The unpressurized dispenser of claim 28, wherein the foamable composition comprises ethanol and isopropanol.

30. The unpressurized dispenser of claim 29, wherein the foamable composition further comprises propylene glycol and a fragrance.

17. An unpressurized dispenser having a dispenser pump for mixing a composition with air and dispensing foam, the dispenser storing a foamable alcohol composition, wherein the foamable alcohol composition comprises:

a) ethanol present in a range from about 60 to about 85% v/v;

b) an effective physiologically acceptable silicone-based surface active agent selected from the group consisting of Bis-PEG-[6-20] dimethicone, (3-(3-hydroxypropyl)-heptamethyltrisiloxane ethoxylated acetate);

a Bis-PEG/PPG 18/6 dimethicone;

polyether-modified polysiloxanes;

polysiloxane betaines; and

combinations thereof, present in a range from about 0.01% to about 10.0% by weight of the total composition; and

c) a foam stabilizing agent; and

d) water present in an amount to balance the total composition to 100% by weight, wherein the composition is mixed with air at low pressure to form a foam.

18. The unpressurized dispenser according to claim 17 wherein the silicone-based surfactant is a Bis-PEG-[6-20] dimethicone.

19. The unpressurized dispenser according to claim 18 wherein the foam stabilizing agent is selected from the group consisting of 2-butoxyethanol, glycerine, butyleneglycol, cetrimonium chloride, and behentrimonium chloride.

20. The unpressurized dispenser according to claim 18 further comprising:

cocoglucoside,

glyceryl oleate,

PEG-200 hydrogenated glyceryl palmate,

PEG-7 glyceryl cocoate, and

dihydroxypropyl PEG-5 linoleammonium chloride.

21. The unpressurized dispenser according to claim 17 wherein the foam stabilizing agent is behentrimonium chloride or glycerine.

22. The unpressurized dispenser according to claim 21 wherein the alcohol/silicone-based surface active agent mixture comprises n-propanol.

31. A foaming antimicrobial composition comprising:

a) a foaming agent comprising a dimethicone copolyol surfactant for foaming, wherein the surfactant is selected from the group consisting of Bis-PEG 8 dimethicone, Bis-PEG 10 dimethicone, Bis-PEG 12 dimethicone, and combinations thereof;

b) from 61% w/w to 75% w/w of an alcohol selected from the group consisting of ethanol, isopropanol, n-propanol, butanol and combinations thereof;

c) up to about 5 wt. % of moisturizer or emollient;

d) water;

wherein there is no more than 1 wt. % of an additional surfactant;

wherein the composition does not include a foam stabilizer,

wherein the composition does not include an additional silicone surfactant, and

wherein the composition is mixed with air at low pressure to form a foam.

32. The antimicrobial composition of claim 31, further comprising from about 0.01 to about 5% weight percent of a preservative.