Conductive polymer patterned electrode for pacing

• US 8,311,606 B2
• Filed: 09/20/2006
• Issued: 11/13/2012
• Est. Priority Date: 09/20/2006
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Jiang, Xiangchun, Ely, Kevin J., Polkinghorne, Jeannette C.
• Primary Examiner(s): Lavert, Nicole F
• Application Number:
  US11/533,644
• Publication Number:
  US 20080071338A1
• Time in Patent Office: 2,246 Days
• Field of Search: 600372-373, 600/395
• US Class Current: 600/395
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/0568 with drug delivery

Abstract

The present invention is an apparatus and method for making a polymer patterned electrode for cardiac pacing and sensing. The electrode surface includes a polymer overlayed on an electrode. The polymer layer is patterned to form an electrode surface consisting of a polymer and a conductive metal surface. The electrode can be made of a high or low impedance electrode by changing the conductivity of the polymer. Furthermore, the electrode surface texture can be optimized with a micro pattern that may enhance the biocompatibility. The polymer may be conductive or insulative.

Claims

1. A method of making an implantable electrode comprising:

forming a polymer layer on a conductive electrode surface; and

etching the conductive polymer layer to remove a portion of the conductive polymer layer in the form of a micro-pattern in the conductive polymer layer that exposes a portion of the conductive electrode surface.

2. The method of claim 1 wherein forming the conductive polymer layer further comprises depositing one or more of the group consisting of polypyrrole, polyethylene glycol, poly(naphthalene), poly(thiophene), PEDOT, Nafion, poly(ethylene) oxide or a combination thereof.

3. The method of claim 1 wherein forming the conductive polymer layer includes depositing the conductive polymer layer on the conductive electrode substrate, the conductive electrode substrate comprising any one of platinum, titanium, platinum iridium, iridium oxide, titanium nitride, titanium oxide, titanium oxynitride, titanium carbide, tantalum oxide, tantalum nitride, tantalum oxynitride, platinum, titanium, tantalum, or combinations thereof.

4. The method of claim 1 wherein the step of etching the conductive polymer layer comprises etching the conductive polymer layer with a laser.

5. The method of claim 1 wherein forming the polymer layer further comprises depositing the conducting polymer using one or more of dip-coating, brush-coating, drop coating, electrochemical deposition, electrospinning, sputtering or bipolar electrodeposited.

6. The method of claims 1 wherein forming the conducting polymer layer further includes forming a layer by physical vapor deposition.

7. The method of claim 1 further comprising loading a drug into or onto the polymer coating.

8. The method of claim 1 further comprising applying a degradable coating over the conductive polymer coating.

9. The method of claim 1 wherein etching the conductive polymer layer further comprises removing a portion of the conductive polymer layer to form a plurality of discrete holes in the conductive polymer to form the micro-pattern that exposes a portion of the conductive electrode surface.

10. The method of claim 1 wherein etching the conductive polymer layer further comprises removing strips of the conductive polymer layer to form the micro-pattern that exposes a portion of the conductive electrode surface.

11. The method according to claim 1, wherein the conductive polymer comprises polypyrrole.

12. The method according to claim 1, further comprising the step of depositing a capacitive coating onto the conductive electrode surface prior to forming the conductive polymer layer.

13. A method of making an implantable electrode comprising:

coating a conductive electrode surface with a conductive polymer layer; and

applying laser energy to the conductive polymer layer to remove a portion of the conductive polymer layer to form a plurality of micro-sized holes in the conductive polymer layer that expose the conductive electrode surface.

14. The method of claim 13 wherein the micro-sized holes have a diameter of no more than 25 microns.