Biopsy tissue marker

• US 8,311,610 B2
• Filed: 01/22/2009
• Issued: 11/13/2012
• Est. Priority Date: 01/31/2008
• Status: Active Grant

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Ranpura, Himanshu M.
• Primary Examiner(s): Cattungal, Sanjay
• Application Number:
  US12/747,895
• Publication Number:
  US 20100331668A1
• Time in Patent Office: 1,391 Days
• Field of Search: 600407-430, 424423-426, 623/1, 623/11, 623/12
• US Class Current: 600/414
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 2090/3925 ultrasonic
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

A biopsy site marker is disclosed. The biopsy site marker includes a first marker element and a second marker element. The first marker element is configured for detection by a first imaging modality. The second marker element is configured for detection by a second imaging modality different from the first imaging modality. The second marker element may be a non-absorbable wire having a predetermined shape and is substantially engaged with the first marker element.

Claims

1. A biopsy site marker comprising:

a first marker element configured for detection by a first imaging modality, wherein the first marker element is a non-absorbable cylinder;

a second marker element configured for detection by a second imaging modality different from the first imaging modality, wherein the second marker element is a non-absorbable wire having a first helical shape positioned around a longitudinal extent of the non-absorbable cylinder of the first marker element; and

a third marker element having a second helical shape overlapped with the first helical shape and positioned around a longitudinal extent of the non-absorbable cylinder of the first marker element.

2. The marker of claim 1, wherein the first marker element is a polymer.

3. The marker of claim 1, wherein the first marker element is formed entirely from non-magnetic material.

4. The marker of claim 1, wherein the non-absorbable wire has a twisted configuration.

5. The marker of claim 1, wherein the second marker element is a shape-memory material.

6. The marker of claim 1, wherein the third non-absorbable marker element is detectable by a third imaging modality and not detectable by the first imaging modality and not detectable by the second imaging modality.

7. The marker of claim 6, wherein the third marker element is substantially engaged with each of the first marker element and the second marker element.

8. The marker of claim 1, wherein the third marker element is a third marker wire.

9. The marker of claim 8, wherein the third marker wire is substantially engaged with the non-absorbable wire.

10. The marker of claim 8, wherein the third marker wire has a twisted configuration.

11. The marker of claim 8, wherein the non-absorbable wire and third marker wire are braided.

12. The marker of claim 7, wherein the third marker element is a polymer coating.

13. The marker of claim 6, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

14. The marker of claim 1, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

15. The marker of claim 1, wherein the second imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

16. The marker of claim 1, further comprising a bioabsorbable cover.

17. A biopsy site marker comprising:

a first marker element configured for detection by a first imaging modality, wherein the first marker element is a non-absorbable cylinder having a cylindrical side surface having at least one hole; and

a second marker element configured for detection by a second imaging modality different from the first imaging modality, wherein the second marker element is a non-absorbable peg substantially engaged with the hole of the first marker element, the non-absorbable peg being configured to extend distally outwardly from the hole away from the cylindrical side surface of the first marker element.

18. The marker of claim 17, wherein the first marker element is a polymer.

19. The marker of claim 17, wherein the first marker element is formed entirely from non-magnetic material.

20. The marker of claim 17, further comprising a third non-absorbable marker element substantially engaged with at least one on the first marker element and the second marker element.

21. The marker of claim 20, wherein the third marker element is detectable by a third imaging modality and not detectable by the first imaging modality and not detectable by the second imaging modality.

22. The marker of claim 20, wherein the third marker element is a polymer coating.

23. The marker of claim 20, wherein the third marker element is a wire.

24. The marker of claim 23, wherein the wire has a twisted configuration.

25. The marker of claim 17, comprising a second hole in the cylindrical side surface of the first marker element and a third marker element formed as a second non-absorbable peg substantially engaged with the second hole, the second non-absorbable peg being configured to extend distally outwardly from the second hole away from the cylindrical side surface of the first marker element.

26. The marker of claim 17, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

27. The marker of claim 17, wherein the second imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

28. The marker of claim 20, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

29. The marker of claim 17, further comprising a bioabsorbable cover.

30. A biopsy site marker comprising:

a first marker element, wherein the first marker element is a non-absorbable material configured for detection by a first imaging modality; and

a second marker element configured for detection by a second imaging modality different from the first imaging modality, wherein the second marker element is a non-absorbable material, and wherein the second marker is a wire having bends to form a predetermined closed geometric shape having a plurality of side segments, and with the first marker element being engaged with one of the side segments.

31. The marker of claim 30, wherein the first marker element is a polymer.

32. The marker of claim 30, wherein the first marker element is formed from at least one of a metal and a metal alloy.

33. The marker of claim 30, wherein the first marker element is a cylinder.

34. The marker of claim 30, wherein the first marker element is a wire.

35. The marker of claim 30, wherein the second marker element is a polymer material.

36. The marker of claim 30, wherein the second marker element is a shape-memory material.

37. The marker of claim 30, wherein the second marker element has one of a pyramid shape, a cube shape, a sphere shape, a rectangular shape, and a square shape.

38. The marker of claim 30, wherein the wire has a twisted configuration.

39. The marker of claim 30, further comprising a third non-absorbable marker element engaged with at least one of the first marker element and the second marker element detectable by a third imaging modality different from the first imaging modality and different from the second imaging modality.

40. The marker of claim 39, wherein the third marker element is substantially engaged with both of the first marker element and the second marker element.

41. The marker of claim 39, wherein the third marker element is a polymer coating.

42. The marker of claim 39, wherein the third marker element is a third marker wire.

43. The marker of claim 42, wherein the third marker wire has a twisted configuration.

44. The marker of claim 42, wherein the third marker element and the second marker element are braided.

45. The marker of claim 39, wherein the third marker element is a cylinder and the third marker element is engaged with one of the side segments of the second marker element different from the side segment engaged by the first marker element.

46. The marker of claim 30, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

47. The marker of claim 30, wherein the second imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

48. The marker of claim 39, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

49. The marker of claim 30, further comprising a bioabsorbable cover that encapsulates the marker.

50. A method for imaging a subcutaneous biopsy cavity comprising:

placing a marker element into the biopsy cavity, wherein the marker element includes

a first marker element, wherein the first marker element is a non-absorbable cylinder;

a second marker element, wherein the second marker element is a non-absorbable wire having a first helical shape positioned around a longitudinal extent of the non-absorbable cylinder of the first marker element; and

a third marker element having a second helical shape overlapped with the first helical shape and positioned around a longitudinal extent of the non-absorbable cylinder of the first marker element;

detecting the first marker element using a first imaging modality; and

detecting the second marker element using a second imaging modality.

51. The method of claim 50, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

52. The method of claim 51, wherein the second imaging modality is a different one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

53. The method of claim 50, wherein the third non-absorbable marker element is substantially engaged with at least one of the first marker element and the second marker element.

54. The method of claim 53, further comprising detecting the third marker element using a third imaging modality, wherein the third imaging modality is different than the first imaging modality and the second imaging modality.

55. The method of claim 54, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

56. A method for imaging a subcutaneous biopsy cavity comprising:

placing a marker element into the biopsy cavity, wherein the marker element includes

a first marker element, wherein the first marker element includes a non-absorbable cylinder having a cylindrical side surface containing at least one hole, and

a second marker element, wherein the second marker element is a non-absorbable peg substantially engaged with the hole of the first marker element and which extends distally outwardly from the hole away from the cylindrical side surface of the first marker element;

detecting the first marker element using a first imaging modality; and

detecting the second marker element using a second imaging modality.

57. The method of claim 56, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

58. The method of claim 57, wherein the second imaging modality is a different one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

59. The method of claim 56, wherein the marker element further includes a third non-absorbable marker element substantially engaged with at least one of the first marker element and the second marker element.

60. The method of claim 59, further comprising detecting the third marker element using a third imaging modality, wherein the third imaging modality is different than the first imaging modality and the second imaging modality.

61. The method of claim 60, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

62. A method for imaging a subcutaneous biopsy cavity comprising:

placing a marker element into the biopsy cavity, wherein the marker element includes

a first marker element, wherein the first marker element includes a non-absorbable material, and

a second marker element, wherein the second marker element is a non-absorbable material substantially engaged with the first marker element, the second marker element being a wire having bends to form a predetermined closed geometric shape having a plurality of side segments, and with the first marker element being engaged with one of the side segments;

detecting the first marker element using a first imaging modality; and

detecting the second marker element using a second imaging modality.

63. The method of claim 62, wherein the first imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

64. The method of claim 62, wherein the second imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, and computed tomography.

65. The method of claim 62, wherein the marker element further includes a third non-absorbable marker element engaged with one of the side segments of the second marker element different from the side segment engaged by the first marker element.

66. The method of claim 65, further comprising detecting the third marker element using a third imaging modality, wherein the third imaging modality is different than the first imaging modality and the second imaging modality.

67. The method of claim 66, wherein the third imaging modality is one of ultrasonography, fluoroscopy, magnetic resonance imaging, X-ray, or computed tomography.

68. The method of claim 66, wherein the predetermined shape is one of a pyramid shape, a polygonal shape, and a sphere shape.