Reduction of AV delay for treatment of cardiac disease
First Claim
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1. A cardiac device, comprising:
- sensing circuitry for receiving electrogram signals representing atrial and ventricular activity;
pacing circuitry for delivering atrial and ventricular pacing pulses;
a controller programmed to operate the device in either a normal operating mode or AV delay reduction (AVDR) mode, wherein the normal mode and the AVDR modes are atrial-triggered or AV sequential pacing modes in which paces are delivered to one or more ventricular sites after an AV delay interval with respect to an atrial sense or pace;
wherein, in the AVDR mode, the controller is programmed to deliver paces to the one or more ventricular sites using an AV delay interval that is shorter than the AV delay interval used in the normal mode;
wherein the controller is programmed to intermittently switch from the normal operating mode to the AVDR mode according to a one or more specified entry conditions and switch from the AVDR mode to the normal operating mode according to one or more specified exit conditions;
an impedance sensor for detecting pulmonary edema;
wherein the controller is programmed to operate in the AVDR mode only if pulmonary edema is not detected and use a determination that pulmonary edema has been detected as an exit condition for exiting the AVDR mode.
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Abstract
An implantable pacing device for delivering ventricular pacing may be configured to intermittently reduce the AVD interval for beneficial effect in patients with compromised ventricular function (e.g., HF patients and post-MI patients). The AVD interval may be reduced in an AVD reduction mode, by shortening the AVD in an atrial triggered ventricular pacing mode or by switching to a non-atrial triggered ventricular pacing mode (e.g., VVI) and delivering paces at a rate above the intrinsic rate. The physiological effects of AVD reduction may be either positive or negative on cardiac output, depending upon the individual patient.
67 Citations
20 Claims
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1. A cardiac device, comprising:
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sensing circuitry for receiving electrogram signals representing atrial and ventricular activity; pacing circuitry for delivering atrial and ventricular pacing pulses; a controller programmed to operate the device in either a normal operating mode or AV delay reduction (AVDR) mode, wherein the normal mode and the AVDR modes are atrial-triggered or AV sequential pacing modes in which paces are delivered to one or more ventricular sites after an AV delay interval with respect to an atrial sense or pace; wherein, in the AVDR mode, the controller is programmed to deliver paces to the one or more ventricular sites using an AV delay interval that is shorter than the AV delay interval used in the normal mode; wherein the controller is programmed to intermittently switch from the normal operating mode to the AVDR mode according to a one or more specified entry conditions and switch from the AVDR mode to the normal operating mode according to one or more specified exit conditions; an impedance sensor for detecting pulmonary edema; wherein the controller is programmed to operate in the AVDR mode only if pulmonary edema is not detected and use a determination that pulmonary edema has been detected as an exit condition for exiting the AVDR mode. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method, comprising:
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delivering pacing pulses to one or more ventricular sites in either a normal operating mode or AV delay reduction (AVDR) mode; wherein the normal mode and the AVDR modes are atrial-triggered or AV sequential pacing modes in which paces are delivered to one or more ventricular sites after an AV delay interval with respect to an atrial sense or pace; wherein, in the AVDR mode, paces are delivered to the one or more ventricular sites using an AV delay interval that is shorter than the AV delay interval used in the normal mode and also shorter than a patient'"'"'s measured intrinsic AV interval; intermittently switching from the normal operating mode to the AVDR mode according to a one or more specified entry conditions and switching from the AVDR mode to the normal operating mode according to one or more specified exit conditions; and
,operating in the AVDR mode only if pulmonary edema is not detected and using a determination that pulmonary edema has been detected as an exit condition for exiting the AVDR mode. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification