Fluid drainage device, delivery device, and associated methods of use and manufacture

• US 8,313,454 B2
• Filed: 03/26/2010
• Issued: 11/20/2012
• Est. Priority Date: 11/20/1997
• Status: Expired due to Term

• Current Assignee: Optonol, Ltd. (Alcon Incorporated)
• Original Assignee: Optonol, Ltd. (Alcon Incorporated)
• Inventors: Yaron, Ira, Nissan, Oded, Goren, Gal
• Primary Examiner(s): DEAK, LESLIE R
• Application Number:
  US12/748,149
• Publication Number:
  US 20100274259A1
• Time in Patent Office: 970 Days
• Field of Search: 604/8, 604/9, 604/264, 606/108
• US Class Current: 604/8
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61M 27/002 Implant devices for drainage of body fluids from one part of the body to another intraocular A61F9/00781; middle ear A61F11/202
• CPC Class Codes: Y10T 83/0596 Cutting wall of hollow work

Abstract

The disclosure provides an intraocular implant for allowing fluid flow from the anterior chamber of an eye, the implant comprising a tube having an inlet end, an outlet end, and a tube passage, wherein the inlet end is adapted to extend into the anterior chamber of the eye, and wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye. The implant may be adapted to drain aqueous humor into a suprachoroidal space or a juxta-uveal space. The disclosure also provides associated delivery devices, methods of use, and methods of manufacture.

Claims

1. A method of implanting an intraocular implant, comprising:

(i) positioning an intraocular implant to be carried by a delivery device;

wherein the intraocular implant comprises a tube having an inlet end, an outlet end, and a tube passage;

wherein the inlet end is adapted to extend into the anterior chamber of the eye;

wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye;

wherein the implant further comprises a flange at one end of the tube, and wherein a surface of the flange is tilted at a first angle relative to a plane perpendicular to a longitudinal axis of the tube;

wherein the delivery device comprises a rodlike instrument and a retention mechanism, wherein the retention mechanism comprises an abutment surface tilted at a second angle relative to a plane perpendicular to a longitudinal axis of the rodlike instrument, wherein the second angle generally corresponds to the first angle;

(ii) forming an incision in the eye;

(iii) directing the implant to a desired implantation location; and

(iv) withdrawing the delivery device.

2. A method according to claim 1, wherein the intraocular implant further comprises one or more side holes.

3. A method according to claim 1, wherein the intraocular implant further comprises a beveled surface at one end of the tube.

4. A method according to claim 1, wherein the intraocular implant further comprises one or more retention projections in the form of one or more spurs.

5. A method according to claim 1, wherein the delivery device comprises a tip for penetrating a tube passage of the implant.

6. A method according to claim 1, wherein the retention mechanism of the delivery device is adapted for preventing the implant from moving up the delivery device during implantation.

7. An intraocular implant in combination with a delivery device, comprising:

an intraocular implant comprising a tube having an inlet end, an outlet end, and a tube passage, wherein the inlet end is adapted to extend into the anterior chamber of the eye, wherein the outlet end is adapted to be implanted adjacent scleral tissue of the eye, wherein the implant further comprises a flange at one end of the tube, and wherein a surface of the flange is tilted at a first angle relative to a plane perpendicular to a longitudinal axis of the tube; and

a delivery device comprising a rodlike instrument and a retention mechanism, wherein the retention mechanism comprises an abutment surface tilted at a second angle relative to a plane perpendicular to a longitudinal axis of the rodlike instrument, wherein the second angle generally corresponds to the first angle;

wherein the intraocular implant is carried by the delivery device.

8. A combination of intraocular implant and delivery device according to claim 7, wherein the intraocular implant further comprises one or more side holes.

9. A combination of intraocular implant and delivery device according to claim 7, wherein the intraocular implant further comprises a beveled surface at one end of the tube.

10. A combination of intraocular implant and delivery device according to claim 7, wherein the intraocular implant further comprises one or more retention projections in the form of one or more spurs.

11. A combination of intraocular implant and delivery device according to claim 7, wherein the delivery device comprises a tip for penetrating a tube passage of the implant.

12. A combination of intraocular implant and delivery device according to claim 7, wherein the retention mechanism of the delivery device is adapted for preventing the implant from moving up the delivery device during implantation.