Endoluminal devices

• US 8,313,503 B2
• Filed: 04/22/2005
• Issued: 11/20/2012
• Est. Priority Date: 04/01/2002
• Status: Expired due to Term

• Current Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Original Assignee: W. L. Gore & Associates (W.L. Gore & Associates)
• Inventors: Cully, Edward H., Vonesh, Michael J., Nackard, K. Jason
• Primary Examiner(s): Houston, Elizabeth
• Application Number:
  US10/907,975
• Publication Number:
  US 20050177186A1
• Time in Patent Office: 2,769 Days
• Field of Search: 623/1.16, 623/1.11, 623/1.12, 623/1.23, 623/1.36, 606/200, 606/108, 606/194, 606/110, 606/113, 606/114, 606/159, 606/198
• US Class Current: 606/200
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61F 2/0105 Open ended, i.e. legs gathered only at one side
• CPC Class Codes: A61F 2/0108 Both ends closed, i.e. legs gathered at both ends
• CPC Class Codes: A61F 2/013 Distal protection devices, i.e. devices placed distally in combination with another endovascular procedure, e.g. angioplasty or stenting
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0015 Kidney-shaped, e.g. bean-shaped
• CPC Class Codes: A61F 2230/005 Rosette-shaped, e.g. star-shaped
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0076 ellipsoidal or ovoid
• CPC Class Codes: A61F 2230/008 paraboloidal
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61F 2230/0093 Umbrella-shaped, e.g. mushroom-shaped

Abstract

A seamless, self-expanding implantable device having a low profile is disclosed along with methods of making and using the same. The implantable device includes a frame cut out of a single piece of material that is formed into a three-dimensional shape. The implantable device may comprise an embolic filter, stent, or other implantable structure. The present invention also allows complicated frame structures to be easily formed from planar sheets of starting material, such as through laser cutting, stamping, photo-etching, or other cutting techniques.

Claims

1. An endovascular device, comprising:

a uni-body frame having a proximal end, a distal end and a longitudinal axis extending therebetween, said uni-body frame having at least two support members, at least two struts and at least two articulated segments, said uni-body frame circumscribing said axis and located at about the distal end;

wherein the at least two support members includes a first support member and at least one secondary support member, wherein the at least one secondary support member is spaced distally from and attached to said first support member, wherein one of the at least one secondary member defines the distal end of the uni-body frame;

wherein the at least two struts extend from the first support member towards said proximal end; and

wherein the at least two articulated segments are located to extend longitudinally between the first support member and the at least one secondary support member; and

a one piece filter media configured to collect embolic material is attached to the first support member, wherein the one piece filter media circumferentially covers said at least two support members circumscribing said axis; and

the distal end of the filter media is circumferentially disposed about a guidewire wherein the circumferentially disposed filter media further comprises at least one point of contact between the filter media and the guidewire, and a majority of the filter media extends beyond the distal end of the uni-body frame.

2. The device of claim 1, wherein at least one of the at least two support members includes at least one radiopaque marker.

3. The device of claim 1, wherein at least one of the at least two struts includes at least one radiopaque marker.

4. The device according to claim 1, wherein the one piece filter media includes a pharmacological agent.

5. The device according to claim 4, wherein said pharmacological agent is selected from the group consisting of anti-thrombotic agent, drug, and combinations thereof.

6. The device according to claim 1, wherein the one piece filter media comprises at least two layers.

7. The device according to claim 6, further comprising a pharmaceutical substance.

8. The device according to claim 1, further comprising an articulation segment on at least one of said at least two struts.

9. The device according to claim 1, wherein the filter media has a substantially windsock configuration.

10. The device according to claim 1, wherein the filter media has a substantially tapered configuration.

11. The device according to claim 1, wherein the struts are configured to be more flexible than the support members.

12. The device according to claim 11, wherein the struts have a different cross-sectional area than the support members.

13. The device of claim 1 wherein the filter media comprises expanded polytetrafluoroethylene.

15. The device according to claim 4, further comprising a radio-opaque marker arranged between the at least two support members.

14. A device, comprising:

a uni-body frame having a proximal end, a distal end and a longitudinal axis extending therebetween, said uni-body frame having at least two support members, a first set of struts, and at least two articulated segments, said uni-body frame circumscribing said axis;

wherein the at least two support members includes a first support member and at least one secondary support member, wherein the at least one secondary support member is spaced distally from and attached to said first support member, wherein one of the at least one secondary member defines the distal end of the uni-body frame, wherein the at least two support members are capable of expanding to a substantially similar outside diameter in order to provide a seal region against a vessel wall;

wherein the first set of struts extends from the first support member towards said proximal end; and

wherein the at least two articulated segments are located to extend longitudinally between the first support member and the at least one secondary support member; and

a filter media including a pharmaceutical substance, wherein the filter media is circumferentially attached to one of the at least two support members, wherein said filter media circumscribes said axis and is configured to collect embolic material, and wherein the distal end of the filter media extends distally beyond the uni-body frame and is circumferentially disposed about a guidewire, wherein the circumferentially disposed filter media further comprises at least one point of contact between the filter media and the guidewire.

16. The device according to claim 14, further comprising radiopaque markers arranged on the uni-body frame.

17. The device according to claim 14, wherein the filter media comprises at least two layers.

18. The device according to claim 17, wherein a pharmaceutical substance is loaded between the two layers.

19. The device according to claim 14, wherein the filter media has a substantially parabolic configuration.