Metallic implantable grafts and method of making same
First Claim
1. An implantable medical graft, comprising:
- a. a generally tubular body member comprising a film selected from the group consisting of metallic and pseudometallic materials and having a luminal wall surface, an abluminal wall surface and a wall thickness intermediate the luminal wall surface and the abluminal wall surface;
b. at least a portion of the body member having a plurality of circumferential corrugations defined by a radially undulating pattern of longitudinally alternating radially extending peaks and valleys in the abluminal wall surface of the body member and a radially undulating longitudinally alternating pattern of radially extending peaks and valleys in the luminal wall surface of the body member, wherein each peak in the luminal surface is longitudinally coincident with each peak in the abluminal surface and each valley in the luminal surface is longitudinally coincident with each valley in the abluminal surface, wherein a plurality of microperforations is disposed through the wall thicknesses composing the coincident peaks and the wall thicknesses composing the coincident valleys and wherein a plurality of microperforations provide fluid migration between the luminal and abluminal wall surfaces; and
c. at least one of a plurality of non-undulating circumferential regions positioned at end regions of the body member.
10 Assignments
0 Petitions
Accused Products
Abstract
Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of the graft. The implantable graft is preferably fabricated by vacuum deposition of metallic and/or pseudometallic materials into either single or multi-layered structures with the plurality of microperforations either being formed during deposition or after deposition by selective removal of sections of the deposited film. The implantable medical grafts are suitable for use as endoluminal or surgical grafts and may be used as vascular grafts, stent-grafts, skin grafts, shunts, bone grafts, surgical patches, non-vascular conduits, valvular leaflets, filters, occlusion membranes, artificial sphincters, tendons and ligaments.
-
Citations
15 Claims
-
1. An implantable medical graft, comprising:
-
a. a generally tubular body member comprising a film selected from the group consisting of metallic and pseudometallic materials and having a luminal wall surface, an abluminal wall surface and a wall thickness intermediate the luminal wall surface and the abluminal wall surface; b. at least a portion of the body member having a plurality of circumferential corrugations defined by a radially undulating pattern of longitudinally alternating radially extending peaks and valleys in the abluminal wall surface of the body member and a radially undulating longitudinally alternating pattern of radially extending peaks and valleys in the luminal wall surface of the body member, wherein each peak in the luminal surface is longitudinally coincident with each peak in the abluminal surface and each valley in the luminal surface is longitudinally coincident with each valley in the abluminal surface, wherein a plurality of microperforations is disposed through the wall thicknesses composing the coincident peaks and the wall thicknesses composing the coincident valleys and wherein a plurality of microperforations provide fluid migration between the luminal and abluminal wall surfaces; and c. at least one of a plurality of non-undulating circumferential regions positioned at end regions of the body member. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
-
-
13. A method of making an implantable medical graft comprising the steps of:
-
a. providing a generally cylindrical substrate having a plurality of circumferentially extending continuous undulations defined by a radially undulating pattern of surfaces disposed between longitudinally alternating radially extending peaks and valleys, patterned along at least a portion of a longitudinal axis of the generally cylindrical substrate and at least one of a plurality of non-undulated circumferential regions positioned at the end regions of the substrate; b. vacuum depositing a graft-forming material onto the generally cylindrical substrate; c. releasing the deposited graft-forming material from the substrate to form a implantable medical graft including circumferential corrugations defined by a radially undulating pattern of longitudinally alternating radially extending peaks and valleys in an abluminal wall surface of the deposited graft-forming material and a radially undulating longitudinally alternating pattern of radially extending peaks and valleys in a luminal wall surface of the deposited graft-forming material, wherein each peak in the luminal surface is longitudinally coincident with each peak in the abluminal surface and each valley in the luminal surface is longitudinally coincident with each valley in the abluminal surface, wherein the peaks and valleys are disposed along at least a portion of the longitudinal axis of the deposited graft-forming material and at least one of a plurality of non-undulated circumferential regions is positioned at the end regions of the deposited graft-forming material; and d. forming a plurality of microperforations wherein a plurality of microperforations provide fluid migration between the luminal and abluminal wall surfaces disposed through the deposited graft-forming material forming the coincident peaks and the coincident valleys. - View Dependent Claims (14, 15)
-
Specification