Integrated pulse oximetry sensor

• US 8,315,682 B2
• Filed: 12/05/2005
• Issued: 11/20/2012
• Est. Priority Date: 12/14/2004
• Status: Expired due to Fees

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Inventors: Such, Olaf, Lauter, Josef, Pinter, Robert, Muehlsteff, Jens
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Fardanesh, Marjan
• Application Number:
  US11/720,887
• Publication Number:
  US 20090240125A1
• Time in Patent Office: 2,542 Days
• Field of Search: 600309-344
• US Class Current: 600/323
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: G01N 2021/3133 with selection of wavelengths before the sample
• CPC Class Codes: G01N 2021/3144 for oxymetry
• CPC Class Codes: G01N 21/3151 using two sources of radiation of different wavelengths G01N21/33 - G01N21/39 take precedence
• CPC Class Codes: G01N 21/35 using infrared light G01N21/39 takes precedence
• CPC Class Codes: G01N 2201/062 LED's
• CPC Class Codes: G01N 2201/0623 Use of a reference LED
• CPC Class Codes: G01N 2201/0625 Modulated LED
• CPC Class Codes: G01N 2201/0627 Use of several LED's for spectral resolution

Abstract

In a medical pulse oximetry sensor (10) at least two light emitting diodes (16, 18) are disposed to emit red light and infrared light through a portion of a subject'"'"'s anatomy with a typically high oxygenated blood throughput. Typically, this area is also relatively narrow, to allow the light to pass through the area with acceptable attenuation, such as a finger or an earlobe. Light emitted from the LEDs (16, 18) is incumbent upon an integrated circuit (22) printed from a single CMOS substrate (21). The integrated circuit (22) includes all preprocessing and post-processing elements needed to convert the detected light signals into a pulse oximetry measurement. These elements include a photodetector (20), a photo pre-amplifier (40), a sampler/holder (42), an analog to digital converter (44), a microprocessor (46) a rangefinder (48), a timing control circuit (50) and an LED control circuit (52). By integrating all pre and post processing functions into the carriage housing (12), the system becomes more efficient, less expensive to manufacture, and more robust to ambient light and x-ray radiation.

Claims

1. A medical pulse oximetry sensor comprising:

a carriage housing adapted to fit snugly about a portion of a subject'"'"'s anatomy with a relatively high oxygenated blood throughput;

a first light emitting diode mounted in the housing for emitting light in the electromagnetic spectrum of the red wavelengths;

a second light emitting diode mounted in the housing for emitting light in the electromagnetic spectrum of the infrared wavelengths;

an integrated CMOS semiconducting component chip mounted in the carriage housing which includes;

at least one photodiode for detecting incumbent light from the first and second light emitting diodes after the emitted light has passed through a blood oxygenated portion of a subject and generating electrical signals indicative thereof;

an amplifier for amplifying the signal from the at least one photodiode;

a microprocessing unit for processing the amplified signals into at least one of pulse oximetry value and plethymographic waveforms;

a light emitting diode control operationally connected to the microprocessing unit that controls light emissions from the first and second light emitting diodes; and

a timing circuit that coordinates processing the signals generated by the photodiode and operations of the light emitting diodes.

2. The medical pulse oximetry sensor as set forth in claim 1, wherein the CMOS semiconducting chip further includes:

a sigma delta modulator for sampling the amplified signals and converting the signals into digital format.

3. The medical pulse oximetry sensor as set forth in claim 2, wherein the CMOS semiconducting chip further includes:

a sample and hold operatively connected to the amplifier for sampling and holding the amplified signals.

4. The medical pulse oximetry sensor as set forth in claim 3, wherein the CMOS semiconducting chip further includes:

an analog to digital converter for digitizing sampled and held amplified signals.

5. The medical pulse oximetry sensor as set forth in claim 1, wherein the CMOS semiconducting chip further includes:

a current to voltage converter for analog modulation and one of frequency and phase multiplexed LED modulation of the signals from the photodiode.

6. The medical pulse oximetry sensor as set forth in claim 1, wherein the CMOS semiconducting chip further includes:

a range finder that selects an amplification range for the amplifier to adjust signal intensities in accordance with characteristics of a measurement site, photodiode efficiency and/or skin color/tone.

7. The medical pulse oximetry sensor as set forth in claim 1, further including:

additional light emitting diodes, each emitting additional wavelengths of electromagnetic radiation.

8. The medical pulse oximetry sensor as set forth in claim 1, wherein the photodiode is integrally formed in the CMOS semiconductor chip.

9. The medical pulse oximetry sensor as set forth in claim 1, further including:

a wireless transmitter for transmitting the calculated pulse oximetry value to at least one of a display console and a data recordation device; and

a battery for providing power to the pulse oximetry sensor.

10. The medical pulse oximetry sensor as set forth in claim 9, wherein the wireless transmitter controls processing the on/off command for the oximetry sensor.

11. The medical pulse oximetry sensor as set forth in claim 9, wherein the wireless transmitter is formed on a separate chip.

12. The medical pulse oximetry sensor as set forth in claim 1, further including:

a cable for providing power to the pulse oximetry sensor and for transmitting the calculated pulse oximetry value to at least one of a display console and a recordation device.

15. The medical pulse oximetry sensor as set forth in claim 1, wherein the carriage housing is formed as a single unit.

16. The medical pulse oximetry sensor as set forth in claim 1, wherein the CMOS chip embeds within the carriage housing.

13. A method of measuring blood oxygen comprising:

emitting pulses of red light from a first LED mounted in a carriage housing adapted to fit snugly about a portion of a subject'"'"'s anatomy with a relatively high oxygenated blood throughput;

emitting pulses of infrared light from a second LED mounted in the carriage housing;

receiving light from the LEDs which has traversed a blood oxygenated portion of a person with a photodiode integrally formed on a CMOS semiconductor chip mounted in the carriage housing and generating electrical signals; and

on said CMOS semiconductor chip, digitizing the electrical signals from the photodiode and processing the digitized electrical signals into a blood oximetry value with an analog-to-digital converter and a processing circuit integrally formed on the CMOS semiconductor chip.

14. The method of measuring blood oxygen as set forth in claim 13, further including:

amplifying the electrical signals generated by the photodiode with an amplifier integrally formed on the CMOS semiconductor chip.

17. A medical pulse oximetry sensor comprising:

a housing configured to fit a portion of a patient'"'"'s anatomy with oxygenated blood throughput;

a first light emitting diode mounted in the housing, the first light emitting diode emitting light of a first spectrum;

a second light emitting diode mounted in the housing, the second light emitting diode emitting light of a second spectrum;

an integrated CMOS semiconductor component chip mounted in the housing and including integrally formed thereon;

a photodiode which detects light from the first and second light emitting diodes which has passed through the portion of the patient'"'"'s anatomy,

an amplifier which amplifies signals from the photodiode,

an analog-to-digital converter which digitizes the amplified signals, and

a light emitting diode controller which controls the first and second light emitting diodes.

18. The sensor as set forth in claim 17, wherein the CMOS semiconductor chip further includes:

a processor which processes the digitized signals into at least one of pulse oximetry values and plethymographic waveforms;

a timing circuit which coordinates the analog-to-digital converter, the processor, and the light emitting diode controller.