Device, method, and system for neural modulation as vaccine adjuvant in a vertebrate subject
First Claim
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1. A method for eliciting an enhanced immune response to one or more immunogen in a vertebrate subject, comprising:
- providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components in a tissue of the vertebrate subject, and administering one or more immunogen to the vertebrate subject,wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence, and are configured to enhance the immune response to the one or more immunogen in the vertebrate subject.
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Abstract
A method for enhancing an immune response in a vertebrate subject is described. The method includes providing at least one energy stimulus configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject, wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence sufficient to enhance an immune response in the vertebrate subject.
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Citations
56 Claims
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1. A method for eliciting an enhanced immune response to one or more immunogen in a vertebrate subject, comprising:
- providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components in a tissue of the vertebrate subject, and administering one or more immunogen to the vertebrate subject,
wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence, and are configured to enhance the immune response to the one or more immunogen in the vertebrate subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
- providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components in a tissue of the vertebrate subject, and administering one or more immunogen to the vertebrate subject,
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41. A method for eliciting an enhanced immune response to an infectious agent in a vertebrate subject comprising:
- providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject,
wherein the at least one energy stimulus and the one or more immunogen are provided in a combination and in a temporal sequence and are configured to elicit an enhanced immune response to a disease caused by the infectious agent in the vertebrate subject. - View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56)
- providing at least one energy stimulus from one or more transducers, wherein the at least one energy stimulus is configured to modulate one or more nervous system components of the vertebrate subject, and administering one or more immunogen to the vertebrate subject,
Specification