Devices and methods for treatment of heart failure and associated conditions
First Claim
1. A method, comprising:
- causing a baroreflex therapy system to be manufactured and made available to a user, the baroreflex therapy system configured to be implantable within a patient and including a blood pressure sensor and a heart rate sensor;
causing an implantable measurement device to be manufactured and made available to the user, the implantable measurement device configured to be implantable proximate a blood vessel of the patient, the implantable measurement device including an electrode; and
causing a control system to be manufactured and made available to the user, the control system configured to be coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically;
determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle;
determine arterial stiffness of the blood vessel based on the impedance;
determine blood pressure and heart rate; and
activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.
4 Assignments
0 Petitions
Accused Products
Abstract
Devices and methods of use identification, treatment, and/or management of heart failure and/or associated conditions. Methods may include providing a baroreflex therapy system including a blood pressure sensor and a heart rate sensor, providing an implantable measurement device proximate a blood vessel of a patient, the implantable measurement device including an electrode, providing a control system coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle, determine arterial stiffness of the blood vessel based on the impedance, determine blood pressure and heart rate, and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.
35 Citations
8 Claims
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1. A method, comprising:
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causing a baroreflex therapy system to be manufactured and made available to a user, the baroreflex therapy system configured to be implantable within a patient and including a blood pressure sensor and a heart rate sensor; causing an implantable measurement device to be manufactured and made available to the user, the implantable measurement device configured to be implantable proximate a blood vessel of the patient, the implantable measurement device including an electrode; and causing a control system to be manufactured and made available to the user, the control system configured to be coupled to the baroreflex therapy system and the implantable measurement device, the control system programmed to automatically; determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle; determine arterial stiffness of the blood vessel based on the impedance; determine blood pressure and heart rate; and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness. - View Dependent Claims (2, 3)
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4. A system, comprising:
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an implantable baroreflex activation device; a blood pressure sensor; a heart rate sensor; an implantable measurement device configured to be implanted proximate a blood vessel of a patient, the implantable measurement device including an electrode; and a control system coupled to the baroreflex activation device, the blood pressure sensor, the heart rate sensor and the implantable measurement device, the control system programmed to automatically; determine an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle; determine arterial stiffness of the blood vessel based on the impedance; determine blood pressure and heart rate; and activate, deactivate or otherwise modulate the baroreflex therapy system to deliver a baroreflex therapy based on the blood pressure, heart rate and arterial stiffness. - View Dependent Claims (5, 6, 7)
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8. A method comprising:
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causing a baroreflex therapy system to be manufactured and made available to a user, the baroreflex therapy system including a blood pressure sensor and a heart rate sensor; causing an implantable measurement device to be manufactured and made available to a user, the implantable measurement device configured to be implanted proximate a blood vessel of a patient, the implantable measurement device including an electrode; causing a control system to be manufactured and made available to the user, the control system coupled to the baroreflex therapy system and the implantable measurement device; and programming the control system with instructions recorded on a tangible medium for operating the control system to deliver a baroreflex therapy, the instructions comprising; determining an impedance of the blood vessel with the implantable measurement device over a time period of at least one cardiac cycle; determining arterial stiffness of the blood vessel based on the impedance; determining blood pressure and heart rate; and activating, deactivating or otherwise modulating the baroreflex therapy system to deliver the baroreflex therapy based on the blood pressure, heart rate and arterial stiffness.
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Specification