Method and system for physiologic control of an implantable blood pump

• US 8,323,173 B2
• Filed: 01/07/2003
• Issued: 12/04/2012
• Est. Priority Date: 01/07/2002
• Status: Active Grant

• Current Assignee: ReliantHeart Inc.
• Original Assignee: MicroMed Technology, Inc (MicroMed Cardiovascular, Inc.)
• Inventors: Benkowski, Robert J, Morello, Gino F
• Primary Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US10/501,112
• Publication Number:
  US 20050131271A1
• Time in Patent Office: 3,619 Days
• Field of Search: 600/17, 623/3.28
• US Class Current: 600/17
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 2230/04 Heartbeat characteristics, e.g. ECG, blood pressure modulation
• CPC Class Codes: A61M 2230/06 Heartbeat rate only
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/178 drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
• CPC Class Codes: A61M 60/237 the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
• CPC Class Codes: A61M 60/422 the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/523 using blood flow data, e.g. from blood flow transducers
• CPC Class Codes: A61M 60/546 of blood flow, e.g. by adapting rotor speed

Abstract

A physiologic control method and system for an implantable blood pump includes operating the pump at a predetermined speed and monitoring the patient'"'"'s diastolic pump flow rate. The predetermined speed is varied in response to the diastolic pump flow rate. The pump speed may further be adjusted in response to the patient'"'"'s heart rate. The speed may be increased and decreased in response to corresponding changes in the diastolic pump flow rate, and increased in response to an increase in heart rate.

Claims

1. A method of controlling a blood pump implanted in a patient, comprising:

operating the pump at a predetermined speed;

monitoring the patient'"'"'s pump flow rate;

extracting the patient'"'"'s diastolic pump flow rate from the pump flow rate, wherein the diastolic pump flow rate is a separately isolated flow contribution below a mean pump flow rate; and

changing the predetermined speed in response to the diastolic pump flow rate, wherein changing the predetermined speed includes increasing the pump speed in response to an increase in the diastolic pump flow rate.

2. The method of claim 1, further comprising:

monitoring the patient'"'"'s heart rate; and

changing the predetermined speed in response to the heart rate.

3. The method of claim 2, wherein changing the predetermined speed includes increasing the pump speed in response to an increase in the heart rate.

4. The method of claim 2, wherein changing the predetermined speed includes increasing the pump speed in response to an increase in the diastolic pump flow rate.

5. The method of claim 2, wherein changing the predetermined speed includes decreasing the pump speed in response to a decreasing in the heart rate.

6. The method of claim 2, wherein changing the predetermined speed includes decreasing the pump speed in response to a decrease in the diastolic pump flow rate.

7. The method of claim 1, wherein changing the predetermined speed includes decreasing the pump speed in response to a decrease in the diastolic pump flow rate.

8. The method of claim 1, further comprising:

setting the predetermined speed of the pump in accordance with activities performed by the patient.

9. The method of claim 8, wherein the activities are sleeping, normal activity or high energy exertion.

10. A pump system, comprising:

a pump; and

a controller having an input for receiving a blood pump flow rate signal, the controller being programmed to extract a separate diastolic pump flow rate from the blood pump flow rate signal and provide a control signal to the pump to vary the speed of the pump in response to the separate diastolic pump flow rate, wherein the separate diastolic pump flow rate is a flow contribution below a mean flow rate.

11. The pump system of claim 10, further comprising an implantable flow measurement device having an output for providing the flow rate signal.

12. The pump system of claim 10, wherein the controller is further programmed to vary the speed of the pump in response to heart rate changes.

13. The pump system of claim 12, wherein the controller is programmed to increase the speed of the pump in response to an increase in at least one of the separate diastolic pump flow rate or the heart rate.

14. The pump system of claim 13, wherein the controller is programmed to decrease the speed of the pump in response to a decrease in the separate diastolic pump flow rate.

15. The pump system of claim 10, wherein the controller is programmed to increase the speed of the pump in response to an increase in the separate diastolic pump flow rate.

16. The pump system of claim 10, wherein the controller is programmed to decrease the speed of the pump in response to a decrease in the separate diastolic pump flow rate.

17. The pump system of claim 10, further comprising an implantable pressure sensor for providing pressure sensor data to the controller.

18. The pump system of claim 17, wherein the pressure sensor data from the pressure sensor is used to derive separate diastolic pump flow rate information.

19. A method of controlling a blood pump implanted in a patient, comprising:

monitoring the patient'"'"'s blood pump flow rate;

extracting the patient'"'"'s diastolic pump flow rate from the pump flow rate, wherein the diastolic pump flow rate is a separately isolated flow contribution below a mean flow rate;

changing a speed of the pump in response to the extracted diastolic pump flow rate; and

increasing the speed of the pump in response to an increase in the extracted diastolic pump flow rate.

20. The method of claim 19, further including the step of decreasing the speed of the pump in response to a decrease in the extracted diastolic pump flow rate.