Detection of bubbles during hemodynamic monitoring when performing automated measurement of blood constituents
First Claim
1. A method of determining the presence of a bubble in a blood access system comprising at least one pressure detector, comprising:
- a. Using the pressure detector to determine a first frequency response of the system at a first time;
b. Using the pressure detector to determine a second frequency response of the system at a second time;
c. Determining if a bubble is present in the system by comparing the first and second frequency responses.
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Abstract
Example embodiments of the present invention provide methods and apparatuses that enable the detection of bubbles so that hemodynamic performance can be assured following an automated blood analyte measurement. An example apparatus according to the present invention comprises a blood access system, adapted to remove blood from a body and infuse at least a portion of the blood back into the body. The infusion of at least a portion of the blood back in to the body can be done in a manner to assure that no bubbles of clinical significance are injected into the patient. Additionally an example embodiment can assess for the presence of bubbles in the fluid column that can affect hemodynamic monitoring performance. If a condition exists where hemodynamic monitoring performance cannot be assured, an example embodiment can provide appropriate warning or corrective actions.
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Citations
15 Claims
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1. A method of determining the presence of a bubble in a blood access system comprising at least one pressure detector, comprising:
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a. Using the pressure detector to determine a first frequency response of the system at a first time; b. Using the pressure detector to determine a second frequency response of the system at a second time; c. Determining if a bubble is present in the system by comparing the first and second frequency responses. - View Dependent Claims (2, 3, 4, 5)
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6. A method of determining the presence, concentration, or both of an analyte in the blood of a patient, comprising:
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a. Placing a blood access system in fluid communication with the circulatory patient, wherein the blood access system comprises at least one pressure sensor, at least one analye sensor, and at least one pump; b. Using the pressure sensor to determine the frequency response of the blood access system at a first time before step c; c. Operating the pump to withdraw blood from the patient to the analyte sensor; d. Operating the analyte sensor to determine the presence, concentration, or both of an analyte in the withdrawn blood; e. Using the pressure sensor to determine the frequency response of the blood access system at a second time after step c; f. Determining if a bubble is present in the blood access system by comparing the frequency response determined at the first time with the frequency response determined at the second time. - View Dependent Claims (7, 8, 9, 10)
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11. A method of detecting bubbles in a hemodynamic monitoring system, comprising:
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a. Determining a frequency response of the system; b. Determining if a bubble is present in the system by comparing the frequency response determined in step a with a baseline frequency response, wherein the baseline frequency response is either (a) a frequency response of the system determined at an earlier time when the system was determined to be free of bubbles, or (b) a combination of frequency responses determined at a plurality of earlier times when the system was determined to be free of bubbles. - View Dependent Claims (12, 13, 14, 15)
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Specification