Fluid transfer devices with fluid bypass and ambulatory infusion devices including same

• US 8,323,247 B2
• Filed: 05/08/2009
• Issued: 12/04/2012
• Est. Priority Date: 05/08/2009
• Status: Active Grant

• Current Assignee: Medtronic Minimed Incorporated (Medtronic Plc)
• Original Assignee: Alfred E. Mann Foundation For Scientific Research
• Inventors: Ring, Lawrence Scott
• Primary Examiner(s): Lucchesi, Nicholas
• Assistant Examiner(s): Zhang, Jenna
• Application Number:
  US12/437,951
• Publication Number:
  US 20100286613A1
• Time in Patent Office: 1,306 Days
• Field of Search: 604/152, 417416-419
• US Class Current: 604/152
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: B33Y 30/00 Apparatus for additive manufacturing; Details thereof or accessories therefor
• CPC Class Codes: F04B 17/042 the solenoid motor being separated from the fluid flow

Abstract

Fluid transfer devices for use in, for example, ambulatory infusion devices, and infusions devices including such fluid transfer devices. The fluid transfer devices may include an external housing tube, an internal housing tube that has a piston lumen with a pump chamber, an outer surface, and a bypass aperture with an inlet associated with the pump chamber and an outlet adjacent to the outer surface, a bypass channel in fluid communication with the bypass aperture outlet, a resilient valve member associated with the bypass aperture outlet, and a piston carried within the piston lumen.

Claims

1. An infusion device, comprising:

a fluid transfer device including

an external housing tube having an inner surface,

an internal housing tube defining a piston lumen having a pump chamber, an outer surface having a perimeter, and a bypass aperture having an inlet associated with the pump chamber and an outlet adjacent to the outer surface and defining a bypass aperture longitudinal axis, at least a portion of the internal housing tube being located within the external housing tube such that at least a portion of the outer surface of the internal housing tube is proximate the inner surface of the external housing tube,

a bypass channel in fluid communication with the bypass aperture outlet,

a resilient valve member that extends around the perimeter of the internal housing tube outer surface and over the bypass aperture outlet, and

a piston carried within the piston lumen and movable between a pull-back position where the pump chamber volume is maximized and a rest position where the pump chamber volume minimized, the piston defining a longitudinal axis that is transverse to the bypass aperture longitudinal axis,

wherein the internal housing tube, resilient valve member and piston are configured and positioned relative to one another such that fluid is drawn into the pump chamber as the piston moves to the pull-back position and the fluid within the pump chamber is forced through the bypass aperture and past resilient valve member as the piston moves to the rest position;

an infusion device outlet operably connected to the fluid transfer device; and

a reservoir operably connected to the fluid transfer device such that the fluid transfer device receives fluid from the reservoir.

2. An infusion device as claimed in claim 1, further comprising:

a housing; and

wherein the fluid transfer device and the reservoir are located within the housing.

3. An infusion device as claimed in claim 1, wherein the reservoir comprises a negative pressure reservoir.

4. An infusion device as claimed in claim 1, wherein

the internal housing tube outer surface includes an indentation that extends around the perimeter of the internal housing tube outer surface;

the bypass aperture outlet is located within the indentation;

the bypass channel extends to the indentation; and

the resilient valve member is located within the indentation.

5. An infusion device as claimed in claim 4, wherein

the indentation comprises an annular indentation;

and

the resilient valve member comprises an annular resilient valve member.

6. An infusion device as claimed in claim 4, further comprising:

a second bypass channel that extends to the indentation and is in fluid communication with the bypass aperture.

7. An infusion device as claimed in claim 1, wherein the resilient valve member comprises an annular resilient valve member.

8. An infusion device as claimed in claim 7, wherein the resilient annular valve member defines a rectangle in a cross-section taken parallel to the longitudinal axis.

9. An infusion device as claimed in claim 1, wherein the external housing tube is annular in cross-section and internal housing tube is substantially annular in cross-section.

10. An infusion device as claimed in claim 1, wherein the bypass channel is defined by the external housing tube inner surface and the internal housing tube outer surface.

11. An infusion device as claimed in claim 10, wherein the internal housing tube outer surface includes longitudinally extending substantially planar surface;

and the bypass channel is defined by the external housing tube inner surface and the internal housing tube substantially planar surface.

12. An infusion device as claimed in claim 1, wherein the piston lumen includes an internal bypass channel that is connected to the bypass aperture inlet.

13. An infusion device as claimed in claim 1, further comprising:

a spring that biases the piston to the rest position; and

an electromagnet that, when actuated, moves the piston to a pull-back position.

14. An infusion device as claimed in claim 1, wherein the bypass channel is not located within the piston.

15. An infusion device, comprising:

a fluid transfer device including

an external housing tube having an inner surface,

an internal housing tube member defining a piston lumen, an outer surface having a perimeter, a longitudinal end, and a bypass aperture located adjacent to longitudinal end and having an inlet associated with the piston lumen and an outlet associated with the outer surface, at least a portion of the internal housing tube being located within the external housing tube such that at least a portion of the outer surface of the internal housing tube is proximate the inner surface of the external housing tube,

a bypass channel in fluid communication with the bypass aperture outlet,

a resilient valve member that extends around the perimeter of the internal housing tube outer surface and over the bypass aperture outlet, and

a piston carried within the piston lumen and configured such that no portion of the bypass channel is located within the piston;

an infusion device outlet operably connected to the fluid transfer device; and

a reservoir operably connected to the fluid transfer device such that the fluid transfer device receives fluid from the reservoir.

16. An infusion device as claimed in claim 15, further comprising:

an inlet valve located adjacent to the internal housing tube longitudinal end.

17. An infusion device, comprising:

a fluid transfer device including

an external housing tube having an inner surface,

an internal housing tube defining a piston lumen, an outer surface having a perimeter, and a bypass aperture having an inlet associated with the piston lumen and an outlet associated with the outer surface, at least a portion of the internal housing tube being located within the external housing tube such that at least a portion of the outer surface of the internal housing tube is proximate the inner surface of the external housing tube,

a bypass channel, defined by the external housing tube inner surface and the internal housing tube outer surface, in fluid communication with the bypass aperture outlet,

a piston carried within the piston lumen and movable relative to the bypass aperture, and

a valve member that covers the bypass aperture outlet at a location in spaced relation to the piston and is movable between an open position that permits flow though the bypass aperture and into the bypass channel and a closed position that prevents flow into the bypass aperture from the bypass channel; and

an infusion device outlet operably connected to the fluid transfer device; and

a reservoir operably connected to the fluid transfer device such that the fluid transfer device receives fluid from the reservoir.

18. An infusion device as claimed in claim 17, further comprising:

a housing; and

wherein the fluid transfer device and the reservoir are located within the housing.

19. An infusion device as claimed in claim 17, wherein the reservoir comprises a negative pressure reservoir.

20. An infusion device as claimed in claim 17, wherein the internal housing tube outer surface includes longitudinally extending substantially planar surface;

and the bypass channel is defined by the external housing tube inner surface and the internal housing tube substantially planar surface.

21. An infusion device as claimed in claim 17, wherein the piston lumen includes an internal bypass channel that is connected to the bypass aperture inlet.

22. An infusion device as claimed in claim 17, wherein the valve member comprises a resilient valve member that extends around the perimeter of the internal housing tube outer surface and over the bypass aperture outlet.

23. An infusion device as claimed in claim 22, wherein

the internal housing tube outer surface includes an indentation that extends around the perimeter of the outer surface;

the bypass aperture outlet is located within the indentation;

the bypass channel extends to the indentation; and

the resilient valve member is located within the indentation.

24. An infusion device as claimed in claim 23, further comprising:

a second bypass channel that extends to the indentation.

25. An infusion device as claimed in claim 17, wherein the external housing tube is annular in cross-section and internal housing tube is substantially annular in cross-section.

26. An infusion device as claimed in claim 17, wherein

the internal housing tube defines a longitudinal end;

the bypass aperture is located adjacent to the internal housing tube longitudinal end; and

the fluid transfer device further comprises an inlet valve located adjacent to the internal housing tube longitudinal end.

27. An infusion device as claimed in claim 17, further comprising:

a spring that biases the piston to a rest position; and

an electromagnet that, when actuated, moves the piston to a pull-back position.

28. An infusion device as claimed in claim 17, wherein

piston lumen has a pump chamber;

the piston is movable between a pull-back position where the pump chamber volume is maximized and a rest position where the pump chamber volume minimized; and

fluid is drawn into the pump chamber as the piston moves to the pull-back position and the fluid within the pump chamber is forced through the bypass aperture and past resilient valve member as the piston moves to the rest position.

29. An infusion device as claimed in claim 28, wherein

the piston moves in a first direction when moving from the pull-back position to the rest position;

and

the fluid flows through the bypass channel in a second direction that is different than the first direction as the piston moves in the first direction.

30. An infusion device as claimed in claim 17, wherein the bypass channel defines an inlet end at the bypass aperture outlet and an outlet end, the infusion device further comprising:

an outlet vale at the outlet end of the bypass channel.

31. An infusion device as claimed in claim 17, wherein no portion of the bypass channel is located within the piston.

32. An infusion device as claimed in claim 17, wherein

the piston defines first and second longitudinal ends and is movable between a rest position and a pull-back position;

and

the bypass aperture is located between the first and second longitudinal ends of the piston when the piston is in the rest position.

33. An infusion device, comprising:

a fluid transfer device including

an external housing tube having an inner surface,

an internal housing tube defining a piston lumen having a pump chamber, an outer surface having a perimeter, and a bypass aperture having an inlet associated with the pump chamber and an outlet adjacent to the outer surface, at least a portion of the internal housing tube being located within the external housing tube such that at least a portion of the outer surface of the internal housing tube is proximate the inner surface of the external housing tube,

a bypass channel in fluid communication with the bypass aperture outlet,

a resilient valve member that extends around the perimeter of the internal housing tube outer surface and over the bypass aperture outlet, and

a piston carried within the piston lumen and movable between a pull-back position where the pump chamber volume is maximized and a rest position where the pump chamber volume minimized,

wherein the internal housing tube, resilient valve member and piston are configured and positioned relative to one another such that fluid is drawn into the pump chamber as the piston moves to the pull-back position and the fluid within the pump chamber is forced through the bypass aperture and past resilient valve member as the piston moves to the rest position, and

wherein the piston moves in a first direction when moving from the pull-back position to the rest position and the fluid flows through the bypass channel in a second direction that is different than the first direction as the piston moves in the first direction;

an infusion device outlet operably connected to the fluid transfer device; and

a reservoir operably connected to the fluid transfer device such that the fluid transfer device receives fluid from the reservoir.

34. An infusion device, comprising:

a fluid transfer device including

an external housing tube having an inner surface,

an internal housing tube defining a piston lumen having a pump chamber, an outer surface having a perimeter, and a bypass aperture having an inlet associated with the pump chamber and an outlet adjacent to the outer surface, at least a portion of the internal housing tube being located within the external housing tube such that at least a portion of the outer surface of the internal housing tube is proximate the inner surface of the external housing tube,

a bypass channel defines an inlet end at the bypass aperture outlet and an outlet end,

a resilient valve member that extends around the perimeter of the internal housing tube outer surface and over the bypass aperture outlet,

a piston carried within the piston lumen and movable between a pull-back position where the pump chamber volume is maximized and a rest position where the pump chamber volume minimized, and

an outlet valve at the outlet end of the bypass channel,

wherein the internal housing tube, resilient valve member and piston are configured and positioned relative to one another such that fluid is drawn into the pump chamber as the piston moves to the pull-back position and the fluid within the pump chamber is forced through the bypass aperture and past resilient valve member as the piston moves to the rest position;

an infusion device outlet operably connected to the fluid transfer device; and

a reservoir operably connected to the fluid transfer device such that the fluid transfer device receives fluid from the reservoir.