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Anti-amyloid beta antibodies conjugated to sialic acid-containing molecules

  • US 8,323,654 B2
  • Filed: 05/26/2010
  • Issued: 12/04/2012
  • Est. Priority Date: 05/14/2007
  • Status: Active Grant
First Claim
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1. An antibody complex comprising:

  • an isolated anti-amyloid beta antibody having (i) a variable heavy chain region including an amino acid sequence selected from the group consisting of SEQ ID NOs;

    42, 44, 46, 47, 48, 49, 50 and 51, and (ii) a variable light chain region including an amino acid sequence selected from the group consisting of SEQ ID NOs;

    43, 45, 52, 53 and 54; and

    sialiac acid-containing molecule conjugated to the antibody.

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