Contrast agents
First Claim
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1. A magnetic resonance contrast agent composition comprising one or more T1 contrast agent portions, and one or more T2 contrast agent portions, wherein said one or more T1 contrast agent portions comprise a paramagnetic metal ion chelate, and wherein said one or more T2 contrast agent portions comprise a cobalt ferrite nanoparticle coated with a SiO2 shell.
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Abstract
The present invention relates generally to multimodal magnetic resonance imaging (MRI) contrast agents. In particular, the present invention provides a MRI contrast agent configured to manipulate both the longitudinal (T1) and transverse (T2) relaxation times of surrounding water proton spins.
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Citations
14 Claims
- 1. A magnetic resonance contrast agent composition comprising one or more T1 contrast agent portions, and one or more T2 contrast agent portions, wherein said one or more T1 contrast agent portions comprise a paramagnetic metal ion chelate, and wherein said one or more T2 contrast agent portions comprise a cobalt ferrite nanoparticle coated with a SiO2 shell.
Specification