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Primer array synthesis and validation

  • US 8,338,093 B2
  • Filed: 12/30/2005
  • Issued: 12/25/2012
  • Est. Priority Date: 12/31/2004
  • Status: Active Grant
First Claim
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1. A method for synthesizing primers from an array of polymers on a solid substrate, said method comprising the steps of:

  • providing a solid substrate, wherein said substrate has a density, wherein a plurality of different known oligonucleotides sequences are located in a plurality of different, known locations on a surface of said substrate;

    attaching a plurality of linkers to the substrate, wherein the plurality of linkers comprises a photogroup, wherein the photo group is a compound selected from the group consisting of compounds represented by the following structural formula;

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