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Conjugated polymers for use in homogeneous and solid state assays

  • US 8,338,532 B2
  • Filed: 03/01/2011
  • Issued: 12/25/2012
  • Est. Priority Date: 01/10/2005
  • Status: Active Grant
First Claim
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1. A water-soluble conjugated polymer comprising a plurality of solubilizing functionalities, said polymer soluble in a polar medium,wherein said polymer comprises a plurality of low bandgap repeat units sufficient for the polymer to form an excited state when the polymer is contacted with incident light in the region of about 450 nm to about 1000 nm in the absence of a target biomolecule, and wherein the polymer can transfer energy from its excited state to a fluorophore to provide a greater than 50% increase in fluorescence emission from the fluorophore than can be achieved by direct excitation.

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