Integrated radiation therapy systems and methods for treating a target in a patient
First Claim
1. A method of developing a treatment plan for a radiation therapy program, comprising:
- acquiring objective target data related to a parameter of a target in the patient by periodically locating a marker with a non-imaging localization modality using a non-ionizing energy, wherein the marker is positioned within the patient; and
developing a treatment plan for use over a plurality of treatment fractions using the objective target data by inputting the parameter of the marker in the treatment plan, wherein the radiation therapy includes continuous treatment during the plurality of treatment fractions.
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Accused Products
Abstract
An integrated radiation therapy process comprises acquiring first objective target data related to a parameter of a target within a patient by periodically locating a marker positioned within the patient using a localization modality. This method continues with obtaining second objective target data related to the parameter of the target by periodically locating the marker. The first objective target data can be acquired in a first area that is apart from a second area which contains a radiation delivery device for producing an ionizing radiation beam for treating the patient. The localization modality can be the same in both the first and second areas. In other embodiments, the first objective target data can be acquired using a first localization modality that uses a first energy type to identify the marker and the second objective target data can be obtained using a second localization modality that uses a second energy type to identify the marker that is different than the first energy type.
164 Citations
36 Claims
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1. A method of developing a treatment plan for a radiation therapy program, comprising:
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acquiring objective target data related to a parameter of a target in the patient by periodically locating a marker with a non-imaging localization modality using a non-ionizing energy, wherein the marker is positioned within the patient; and developing a treatment plan for use over a plurality of treatment fractions using the objective target data by inputting the parameter of the marker in the treatment plan, wherein the radiation therapy includes continuous treatment during the plurality of treatment fractions. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method of developing a treatment plan for radiation therapy, comprising:
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periodically locating a marker in a reference frame external to a patient with a non-imaging localization modality using a non-ionizing energy, wherein the marker is positioned within the patient at a site relative to a target in the patient; and simulating treatment using the periodic locations of the marker and a predetermined multi-fraction treatment plan wherein the simulated treatment includes continuous treatment during the multi-fraction treatment plan. - View Dependent Claims (13, 14, 15, 16, 17, 18, 19)
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20. A method of developing a treatment plan for radiation therapy, comprising:
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periodically locating a plurality of markers in a reference frame external to a patient with a non-imaging localization modality using a non-ionizing energy, wherein the markers are positioned within the patient relative to a target in the patient; characterizing a parameter of the target by comparing relative positions between the markers; and inputting the parameter of the markers in a treatment plan, which spans multiple treatment fractions, for irradiating the patient with an ionizing radiation beam wherein the radiation therapy includes continuous treatment during the multiple treatment fractions. - View Dependent Claims (21, 22, 23)
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24. A method for developing a treatment plan for treating a target within a patient using radiation therapy, comprising:
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periodically localizing a marker positioned within the patient with a non-imaging localization system using non-ionizing energy to determine locations of the marker in a reference frame external to the patient; determining a parameter of the target within the patient based on the location of the marker in the reference frame; and inputting the parameter of the target into a treatment plan for irradiating the patient with an ionizing radiation beam wherein the treatment plan is designed to cover multiple treatment fractions wherein the radiation therapy treatment plan includes continuous treatment during the multiple treatment fractions. - View Dependent Claims (25, 26, 27, 28, 29, 30)
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31. A method of developing a treatment plan for radiation therapy, comprising:
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obtaining images of a target in a patient and of a marker positioned within the patient using an imaging modality; periodically locating the marker in a reference frame external to the patient using a non-imaging localization modality different than the imaging modality; defining a parameter of the target based on the locations of the marker in the reference frame; and inputting the parameter of the target into a plan for controlling a radiation delivery device wherein the plan includes a multi-fraction treatment plan wherein the radiation therapy includes continuous treatment during the multi-fraction treatment. - View Dependent Claims (32, 33)
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34. A method for developing a treatment plan for radiation therapy, comprising:
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obtaining images of a target in a patient and of a marker positioned within the patient using an imaging modality; periodically locating the marker in a reference frame external to the patient using a non-imaging localization modality different than the imaging modality; and instructing the patient to control a body function based on the locations of the marker during a fractional treatment of the treatment plan wherein the radiation therapy includes continuous treatment during the plurality of treatment fractions.
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35. A method for developing a treatment plan for radiation therapy, comprising:
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periodically locating a marker positioned within a patient with respect to a reference frame external to the patient using a non-imaging localization modality; and training the patient to control a body function based on the periodic locations of the marker in the reference frame during a fractional treatment of the treatment plan wherein the radiation therapy includes continuous treatment during the plurality of treatment fractions.
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36. A method of integrating planning and setup procedures in radiation therapy, comprising:
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developing a multi-fraction treatment plan for treating a target within the patient by (a) periodically locating a marker positioned within the patient with respect to a reference frame external to the patient using a non-imaging localization modality and (b) determining target data based on the marker locations wherein the radiation therapy includes continuous treatment during the plurality of treatment fractions; subsequently determining whether the target is in accordance with the target data by periodically locating the marker on a day that the patient is scheduled to be irradiated using the localization modality; and positioning the patient in an external reference frame of a radiation delivery device by periodically locating the marker in the external reference frame of the radiation delivery device.
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Specification