Neural monitoring sensor

• US 8,343,079 B2
• Filed: 08/16/2010
• Issued: 01/01/2013
• Est. Priority Date: 10/18/2007
• Status: Active Grant

• Current Assignee: Innovative Surgical Solutions, LLC (Johnson & Johnson)
• Original Assignee: Innovative Surgical Solutions, LLC (Johnson & Johnson)
• Inventors: Bartol, Stephen, Wybo, Christopher
• Primary Examiner(s): Dougherty, Sean P
• Assistant Examiner(s): Stout, Michael C
• Application Number:
  US12/856,970
• Publication Number:
  US 20110230782A1
• Time in Patent Office: 869 Days
• Field of Search: 600/301, 600/595, 600/546
• US Class Current: 600/595
• CPC Class Codes: A61B 2505/05 Surgical care
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61B 2560/0412 Low-profile patch shaped housings
• CPC Class Codes: A61B 2562/0219 Inertial sensors, e.g. accelerometers, gyroscopes, tilt switches
• CPC Class Codes: A61B 5/1104 induced by stimuli or drugs; A61B5/1102 takes precedence; investigating medicinal preparations G01N33/15
• CPC Class Codes: A61B 5/1106 to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
• CPC Class Codes: A61B 5/1107 Measuring contraction of parts of the body, e.g. organ, muscle apparatus for measuring work or force in general G01L
• CPC Class Codes: A61B 5/389 Electromyography [EMG]
• CPC Class Codes: A61B 5/395 Details of stimulation, e.g. nerve stimulation to elicit EMG response
• CPC Class Codes: A61B 5/4029 for evaluating the peripheral nervous systems A61B5/24 takes precedence
• CPC Class Codes: A61B 5/4519 Muscles A61B5/389, A61B5/224 take precedence
• CPC Class Codes: A61B 5/4893 Nerves
• CPC Class Codes: A61B 5/6828 Leg
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure
• CPC Class Codes: A61B 5/7217 of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
• CPC Class Codes: A61B 5/7239 using differentiation including higher order derivatives

Abstract

A sensing device for detecting a muscle event includes a mechanical sensor, such as an accelerometer, that is configured to provide a signal corresponding to a mechanical movement of a muscle, a plurality of electrodes disposed on the sensing device; and a contact detection device coupled with the plurality of electrodes and configured to detect if the sensing device is in contact with a subject.

Claims

1. A sensing device for detecting an induced muscle event of a subject comprising:

a mechanical sensor configured to be placed in contact with the skin of the subject, the mechanical sensor including an accelerometer configured to monitor an acceleration response of a muscle, the acceleration response including an acceleration attributable to a depolarization of a nerve innervating the muscle the mechanical sensor further configured to provide a mechanomyography output signal corresponding to the monitored muscle acceleration response;

wherein the sensing device is configured to detect the induced muscle event from the mechanomyography output signal, the induced muscle event being attributable to the depolarization of the nerve innervating the muscle in response to a provided electrical stimulus;

wherein detecting the induced muscle event includes calculating a time derivative of acceleration from the mechanomyography output signal, and comparing time derivative of acceleration to a threshold.

2. The sensing device of claim 1, further including a receiver module configured to receive the mechanomyography output signal from the mechanical sensor and to detect the induced muscle event.

3. The sensing device of claim 2, wherein the receiver module is further configured to provide an alert if a muscle event is detected.

4. The sensing device of claim 3, wherein the alert includes a visual alert.

5. The sensing device of claim 1, further including a wireless data transmitter.

6. The sensing device of claim 1, wherein the acceleration response includes an acceleration in a direction normal to the skin of the subject.

7. The sensing device of claim 1, further comprising:

a plurality of electrodes coupled with the mechanical sensor; and

a contact detection device coupled with the plurality of electrodes and configured to detect if the mechanical sensor is in contact with the subject.

8. The sensing device of claim 7, wherein the contact detection device is configured to energize the mechanical sensor when the sensing device is in physical contact with the subject.

9. The sensing device of claim 7, wherein the contact detection device is configured to detect if the sensing device is in contact with the subject by monitoring a capacitance between the plurality of electrodes, and by comparing the monitored capacitance to a threshold.

10. The sensing device of claim 7, wherein the contact detection device is configured to detect if the sensing device is in contact with the subject by monitoring an electric field between the plurality of electrodes and by comparing the electric field to a threshold.

11. The sensing device of claim 7, wherein the contact detection device is configured to detect if the sensing device is in contact with the subject by monitoring a relative electrical voltage between the plurality of electrodes and by comparing the voltage to a threshold.

12. The sensing device of claim 7, wherein the contact detection device is configured to provide an alert if contact between the sensing device and the subject is not detected.

13. The sensing device of claim 7, wherein the plurality of electrodes are needle electrodes.

14. The sensing device of claim 7, wherein the plurality of electrodes are surface electrodes.

15. The sensing device of claim 7, wherein the mechanical sensor is physically disposed between two of the plurality of electrodes.

16. A sensing device for detecting an induced muscle event of a subject comprising:

a mechanical sensor configured to provide a mechanomyography output signal corresponding to a mechanical response of a muscle of the subject, the mechanical response being attributable to a depolarization of a nerve innervating the muscle;

an electrical sensor configured to monitor an electrical parameter of the subject, the electrical sensor including a plurality of electrodes; and

a contact detection device coupled to the electrical sensor and configured to detect if the sensing device is in physical contact with the subject; and

a receiver in communication with the mechanical sensor and the contact detection device;

the receiver configured to;

receive the mechanomyography output signal from the mechanical sensor;

detect the of an induced muscle event from the received mechanomyography output signal, the induced muscle event being attributable to the depolarization of the nerve innervating the muscle in response to a provided electrical stimulus;

provide an alert if an induced muscle event is detected; and

wherein the receiver is configured to detect the induced muscle event by calculating a time derivative of acceleration from the mechanomyography output signal, and comparing the calculated-time derivative of acceleration to a threshold.

17. The sensing device of claim 16, wherein the receiver is further configured to provide an alert if the contact detection device detects that the sensing device is not in physical contact with the subject.

18. The sensing device of claim 16, wherein the threshold increases as a function of accelerometer peak amplitude.

19. The sensing device of claim 16, wherein the contact detection device includes a power circuit configured to monitor a capacitance between the plurality of electrodes and to energize the mechanical sensor when a threshold capacitance is detected.

20. The sensing device of claim 16, wherein the mechanical sensor is configured to be placed in contact with the skin of the subject;

and

wherein the mechanical sensor is configured to monitor the mechanical movement of the muscle along an axis that is substantially normal to the skin.

21. A system comprising:

a mechanical sensor configured to be placed in contact with the skin of the subject, the mechanical sensor including an accelerometer configured to monitor an acceleration response of a muscle, the acceleration response including a response attributable to a depolarization of a nerve innervating the muscle, the mechanical sensor further configured to provide a mechanomyography output signal corresponding to the monitored muscle acceleration response;

a receiver configured to detect an induced muscle event from the mechanomyography output signal, the induced muscle event being attributable to the depolarization of the nerve innervating the muscle in response to a provided electrical stimulus; and

wherein the receiver is configured to detect the induced muscle event by calculating a time derivative of acceleration from the mechanomyography output signal, and comparing the calculated-time derivative of acceleration to a threshold.

22. The system of claim 21, further comprising:

a plurality of electrodes coupled with the mechanical sensor; and

a contact detection device coupled with the plurality of electrodes and configured to detect if the mechanical sensor is in contact with the subject.

23. The system of claim 21, wherein the receiver is further configured to provide an alert if the induced muscle event is detected.