Device for metered administration of a liquid product

• US 8,343,099 B2
• Filed: 03/23/2006
• Issued: 01/01/2013
• Est. Priority Date: 03/24/2005
• Status: Expired due to Fees

• Current Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Original Assignee: Roche Diagnostics International AG (Roche Holding AG)
• Inventors: Peter, Daniel, Spoerri, Beat
• Primary Examiner(s): Sirmons, Kevin
• Assistant Examiner(s): Hall, Deanna K
• Application Number:
  US11/388,216
• Publication Number:
  US 20070017512A1
• Time in Patent Office: 2,476 Days
• Field of Search: 604/131, 604/154, 128/DIG.1
• US Class Current: 604/131
• CPC Class Codes: A61M 2005/14264 with means for compensating influence from the environment
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/14566 with a replaceable reservoir for receiving a piston rod of the pump
• CPC Class Codes: A61M 5/16831 Monitoring, detecting, signalling or eliminating infusion flow anomalies low-level float-valves causing cut-off A61M5/40; indicating or recording presence, absence or direction of flow in general G01P13/0066

Abstract

A device for metered administration of a liquid product including a container for the product, a delivery mechanism which acts on the product located in the container and delivers product from the container by means of an axial output movement in a delivery direction, and an inherently axially rigid housing support structure which supports the container in and counter to the delivery direction, wherein the housing support structure has, over the axial length of the container, an axial thermal expansion coefficient which, within a temperature range in which the device is used, corresponds at least substantially to the axial thermal expansion coefficient of the container.

Claims

1. A device for metered administration of a liquid product, said device comprising:

a) a glass container for the product,

b) delivery means which acts on the product located in the container and delivers product from the container by means of an axial output movement in a delivery direction, and

c) an inherently axially rigid housing support structure formed as a sleeve-shaped body which supports the container in and counter to the delivery direction, wherein

d) the housing support structure having, over the axial length of the container, an axial thermal expansion which, within a temperature range in which the device is used, differs by about 500% or less from the axial thermal expansion of the container.

2. The device according to claim 1, wherein the housing support structure is made of a material which, within the temperature range in which the device is used, has a coefficient of thermal expansion corresponding at least substantially to the coefficient of thermal expansion of the material from which the container is made.

3. The device according to claim 1, wherein the coefficient of thermal expansion of the material of the housing support structure and the coefficient of thermal expansion of the material of the container differ from one another by at most about 500%.

4. The device according to claim 1, further comprising a support shoulder oriented transversely with respect to the delivery direction and serving as an abutment for the container is formed in one piece by the housing support structure or in a releasable, axially rigid engagement with the housing support structure.

5. The device according to claim 4, further comprising a counteracting support shoulder oriented transversely with respect to the delivery direction and serving as a counter-abutment to the support shoulder for the container is in a releasable, axially rigid engagement with the housing support structure or is formed in one piece by the housing support structure.

6. The device according to claim 1, further comprising a support shoulder and the counteracting support shoulder cooperating to fix the container in and counter to the delivery direction.

7. The device according to claim 1, wherein the housing support structure forms a receiving compartment with a support shoulder projecting inwards transversely with respect to the delivery direction and with an opening which lies opposite the support shoulder and through which the container can be inserted into the receiving compartment, and in that the device has a closure element which, in a releasable engagement with an engaging means of the housing support structure, closes the opening of the receiving compartment and forms for the container a counteracting support shoulder lying opposite the support shoulder.

8. The device according to claim 7, wherein the housing support structure, in an axial section extending at least from the support shoulder to the counteracting support shoulder, has at least substantially the same thermal expansion.

9. The device according to claim 7, wherein the housing support structure, in an axial section extending at least from the support shoulder to the counteracting support shoulder, is formed in one piece.

10. The device according to claim 1, wherein the housing support structure axially supports the delivery means.

11. The device according to claim 10, further comprising a force sensor for at least one of occlusion detection and leakage detection, wherein the delivery means is supported on the housing support structure via the force sensor counter to the delivery direction.

12. The device according to claim 11, wherein the delivery means, counter to an elastic restoring force of the force sensor, is movable counter to the delivery direction relative to the housing support structure.

13. The device according to claim 11, the device further comprising a contact element against which the force sensor presses when the delivery means executes the output movement, wherein at least one of the contact element or the force sensor, in adjustment engagement with the housing support structure or with the delivery means, is moved into an adjustment position and secured in the adjustment position in such a way that an axial play between the delivery means and the housing support structure is reduced.

14. The device according to claim 11, wherein the housing support structure axially guides the delivery means.

15. The device according to claim 14, wherein the housing support structure in the delivery direction forms an abutment for the delivery means.

16. The device according to claim 15, wherein the housing support structure is formed in one piece, at least in an axial section which supports the delivery means in and counter to the delivery direction.

17. The device according to claim 1, further comprising a bearing body which axially supports the delivery means and which is axially guided by the housing support structure.

18. The device according to claim 17, wherein the housing support structure, at least over an axial section which supports the bearing body in and counter to the delivery direction, has an axial thermal expansion which corresponds at least substantially to the axial thermal expansion of the bearing body over its axial section measured between the support locations.

19. The device according to claim 18, wherein the bearing body has in an axial section, per unit of axial length, an axial thermal expansion corresponding at least substantially to the axial thermal expansion of the container measured per unit of axial length.

20. The device according to claim 17, wherein the delivery means comprises a drive member and an output member that projects axially into the container in the delivery direction, these members being in engagement with one another in such a way that a drive movement of the drive member effects the output movement executed by the output member, and in that the support structure, at least over an axial section extending from the engagement between the drive member and the output member to a front end of the output member in the delivery direction, has an axial thermal expansion corresponding at least substantially to the axial thermal expansion of the output member measured between the engagement point and the front end of the output member.

21. The device according to claim 20, wherein, in an axial section extending from a bearing point of the drive member to the front end of the output member, the support structure has at least substantially the same thermal expansion as the delivery means, measured from the bearing point of the drive member to the front end of the output member.

22. The device according to claim 21, wherein the output member, from the engagement point to its front end, has, per unit of axial length, an axial thermal expansion corresponding at least substantially to the axial thermal expansion of the container measured per unit of axial length.

23. The device according to claim 22, wherein the axial thermal expansions compared to one another differ by at most about 500%.

24. The device according to claim 22, wherein the axial thermal expansions compared to one another differ by at most about 300%.

25. The device according to claim 1, further comprising a housing shell structure surrounding the housing support structure.

26. A device for administering a dose of a substance, the device comprising:

a container for the substance, the container having an axial length and an axial coefficient of thermal expansion, the container being formed from glass;

a delivery mechanism which acts on the substance, and

a support structure comprising a first support shoulder disposed proximate a distal end of the support structure projecting substantially transversely with respect to a delivery direction which supports the container in the delivery direction and a second support shoulder disposed proximate a proximal end of the support structure projecting substantially transversely with respect to the delivery direction which supports the container counter to the delivery direction,

wherein the support structure further comprises a distal opening sized and shaped to accommodate passage of the container into a receiving compartment of the support structure and a closure element configured to close the distal opening, wherein the closure element forms the first support shoulder and is non-destructively releasably coupled to the device, and

wherein the support structure is formed as a sleeve-shaped body and has, over the axial length of the container, an axial coefficient of thermal expansion which, within a temperature range in which the device is used, differs by about 500% or less from the axial thermal expansion of the container.

27. The device according to claim 26, wherein the coefficient of thermal expansion of the support structure and the coefficient of thermal expansion of the container differ by at most 500%.

28. The device according to claim 26, wherein the support structure is formed from at least one of a metal and a metal alloy.

29. The device according to claim 26, wherein the support structure is configured such that a distal end of the container abuts the first support shoulder and a proximal end of the container abuts the second support shoulder.