Injection device

• US 8,343,110 B2
• Filed: 05/27/2005
• Issued: 01/01/2013
• Est. Priority Date: 05/28/2004
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: Cilag Gmbh International (Johnson & Johnson)
• Inventors: Harrison, Nigel, Habeshaw, Rosemary
• Primary Examiner(s): Sirmons, Kevin C
• Assistant Examiner(s): Scott, Brandy C
• Application Number:
  US11/579,359
• Publication Number:
  US 20080312606A1
• Time in Patent Office: 2,776 Days
• Field of Search: 604/218, 604/220, 604/219, 604/233, 604/235, 604/228
• US Class Current: 604/218
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/3202 Devices for protection of the needle before use, e.g. caps A61M5/50 takes precedence; for infusion spikes A61M5/1626; protectors for sharps A61B50/3001
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/326 Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user

Abstract

A syringe is received within a housing, the syringe having a bore terminating at a forward end in a hypodermic needle and at a rearward end in a flared opening in which a bung having a bore surrounded by a skirt is insertod. A drive element has a forward end consisting of a substantially flat annular region that bears upon the skirt of the bung and surrounds a conical middle region that is received in the bore of the bung. An actuator advances the drive element so as to advance the bung and discharge the contents through the needle. The opening in the rear of the synnge is flared by being provided with a radius. The combination of the radius at the opening and the projecting conical middle region of the drive element allows misalignments of the two to be managed during automated assembly.

Claims

1. An injection device comprising:

a housing having a trigger projecting though the housing;

a hypodermic syringe, including a syringe body terminating at one end in a hypodermic needle, said hypodermic syringe received within the housing, the syringe having a bore terminating at a forward end in a discharge nozzle and at a rearward end in a flared opening in which a discharge piston having a bore at a rearward end portion thereof is inserted;

a drive element having a forward end consisting of a substantially flat edge region that is adapted to bear upon the rearward end of the discharge piston of the syringe and surrounds a projecting middle region which continuously tapers from the substantially flat edge region to a closed end neb and that is adapted to be received in the bore at the rearward end portion of the discharge piston; and

an actuator a drive spring actuatable by the trigger for advancing the syringe from a refracted position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle extends from an aperture in the housing and for advancing the drive element so as to advance the discharge piston and discharge the contents of the syringe through the discharge nozzle.

2. An injection device according to claim 1 in which the flared opening in the syringe and the substantially flat edge and projecting middle regions of the forward end of the drive element are so shaped and dimensioned that axial misalignment between the syringe and the drive element during assembly of the injection device are corrected by, firstly, the projecting middle region of the forward end of the drive element riding up the flared opening of the syringe to a point at which, secondly, the substantially flat edge region of the forward end of the drive element rides up the flared opening of the syringe to align the drive element in the bore of the syringe.

3. An injection device according to claim 2 in which the line formed by the intersection of the flared opening of the syringe and a plane that passes through the axis of the syringe bore possesses a radius of curvature of between 33% and 100% of the radius of the syringe bore.

4. An injection device according to claim 2 in which the line formed by the intersection of the flared opening of the syringe and a plane that passes through the axis of the syringe bore possesses a radius of curvature of between 1 mm and 3 mm.

5. An injection device according to claim 3 in which the said radius of curvature is an average radius of curvature.

6. An injection device according to claim 3 in which the said radius of curvature is a minimum radius of curvature.

7. An injection device according to claim 3 in which the said radius of curvature is greater than the maximum radial extent of the substantially flat edge region of the forward end of the drive element.

8. An injection device according to claim 7 in which the said radius of curvature is at least 50% greater than the maximum radial extent of the substantially flat edge region of the forward end of the drive element.

9. An injection device according to claim 7 in which the said radius of curvature is at least 70% greater than the maximum radial extent of the substantially flat edge region of the forward end of the drive element.

10. An injection device according to claim 1 in which the flared opening of the syringe is substantially a surface of revolution about the axis of the syringe bore.

11. An injection device comprising:

a housing having a trigger projecting through the housing, said housing adapted to receive a hypodermic syringe, including a syringe body terminating at one end in a hypodermic needle, said hypodermic syringe having a bore terminating at a forward end in a discharge nozzle and at a rearward end in a flared opening in which a discharge piston having a bore at a rearward end portion thereof is inserted; and

a drive element that is adapted to bear upon the rearward end of the discharge piston of the syringe; and

an actuator a drive spring actuatable by the trigger for advancing the syringe from a refracted position in which the discharge nozzle is contained within the housing to an extended position in which the discharge nozzle extends from an aperture in the housing for advancing the drive element so as to advance the discharge piston and discharge the contents of the syringe through the discharge nozzle, the forward end of the drive element consisting of a substantially flat edge region surrounding a projecting middle region which continuously tapers from the substantially flat edge region to a closed end neb and that is adapted to be received in the bore at the rearward end portion of the discharge piston.

12. An injection device according to claim 11 in which the forward end of the drive element has a cross-sectional area in the range 6.5 mm² to 110 mm².

13. An injection device according to claim 12 in which the forward end of the drive element has a cross-sectional area of 27.3 mm²±

8%.

14. An injection device according to claim 11 in which the forward end of the drive element is substantially circular in cross-section.

15. An injection device according to claim 14 in which the forward end of the drive element has a radius in the range 1.45 mm to 5.9 mm.

16. An injection device according to claim 15 in which the forward end of the drive element has a radius of 2.95 mm±

4%.

17. An injection device according to claim 11 in which the substantially flat edge region of the forward end of the drive element accounts for between 25% and 50% of the total area of the forward end of the drive element.

18. An injection device according to claim 17 in which the substantially flat edge region of the forward end of the drive element accounts for 37±

3% of the total area of the forward end of the drive element.

19. An injection device according to claim 11 in which the substantially flat edge region of the forward end of the drive element is substantially annular.

20. An injection device according to claim 19 in which the inner diameter of the substantially flat annular region is 61±

2% of the outer diameter.

21. An injection device according to claim 11 in which the projecting middle region of the forward end of the drive element is substantially circular in shape.

22. An injection device according to claim 11 in which the projecting middle region of the forward end of the drive element tapers at an average angle of between 35±

10°

to the longitudinal axis of the drive element.

23. An injection device according to claim 11 in which the projecting middle region of the forward end of the drive element is substantially conical or frustoconical.

24. An injection device according to claim 23 in which the conical or frustoconical region of the forward end of the drive element has an included cone angle of 65±

5°

.