Sample measurement device, sample measurement system and sample measurement method

• US 8,344,733 B2
• Filed: 03/27/2009
• Issued: 01/01/2013
• Est. Priority Date: 03/27/2008
• Status: Active Grant

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Inventors: Nakamura, Toshifumi, Shinno, Teppei
• Primary Examiner(s): Koval, Melissa
• Assistant Examiner(s): Baldridge, Benjamin M
• Application Number:
  US12/812,109
• Publication Number:
  US 20100283488A1
• Time in Patent Office: 1,376 Days
• Field of Search: 324/532
• US Class Current: 324/532
• CPC Class Codes: G01N 27/327 Biochemical electrodes , e.g. electrical or mechanical details for in vitro measurements
• CPC Class Codes: G01N 27/3274 Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration coding of calibration information G01N33/48771

Abstract

A sample measurement device (110), in which a biosensor (30) having an electrode is mounted, voltage is applied to the electrode, and the concentration of a specific component in a sample deposited on the biosensor (30) is measured, comprises a voltage source (19) configured to apply voltage to the electrode, a time measurement component (22), and a controller (18) configured to control the voltage to be applied and measure the concentration of the specific component. The time measurement component (22) measures a detection time, which is the length of time between the mounting of the biosensor (30) and the deposition of a sample on the biosensor (30). The controller (18) changes a set value for measuring the concentration of a specific component according to the detection time. Consequently, measurement accuracy can be improved regardless of the temperature of the biosensor (30).

Claims

1. A sample measurement device, in which a biosensor having an electrode is mounted, voltage is applied to the electrode by the sample measurement device, and the concentration of a specific component in a sample deposited on the biosensor is measured, said sample measurement device comprising:

a voltage source that applies voltage to the electrode;

a time measurement component; and

a controller that controls the voltage that is applied and that measures the concentration of the specific component,

wherein the time measurement component measures a detection time, which is the length of time from the mounting of the biosensor until the sample is deposited on the biosensor, and

the controller changes a set value for measuring the concentration of the specific component, according to the detection time.

2. The sample measurement device according to claim 1,

wherein the set value is a measurement time for measuring the concentration of the specific component.

3. The sample measurement device according to claim 2,

wherein the shorter is the detection time, the more the controller extends the measurement time.

4. The sample measurement device according to claim 1,

wherein the set value is a value of the voltage applied to the electrode.

5. The sample measurement device according to claim 1,

wherein the controller:

determines whether or not the detection time is within a specified length of time; and

changes the set value when it is determined that the detection time is within the specified length of time.

6. The sample measurement device according to claim 1,

further comprising a temperature measurement component configured to measure an environment temperature,

wherein the controller further changes the set value according to the measured environment temperature.

7. The sample measurement device according to claim 1,

further comprising a hematocrit value calculation unit,

wherein the controller further changes the set value according to the hematocrit value calculated by the hematocrit value calculation unit.

8. The sample measurement device according to claim 1,

wherein the controller chooses a set value from a plurality of set values, and

the plurality of set values consist of a

measurement time for measuring the concentration of the specific component, and a value of the voltage applied to the electrode.

9. The sample measurement device according to claim 1,

wherein the controller sets the set value according to a type of sample.

10. The sample measurement device according to claim 1,

wherein there is a plurality of types of specific components in a sample, and

the controller changes the set values for the concentrations of the plurality of types of specific components.

11. A sample measurement system, comprising:

the sample measurement device according to claim 1; and

a biosensor that is mounted to the sample measurement device.

12. The sample measurement system according to claim 11,

wherein the sample measurement system comprises a plurality of biosensors, and

the sample measurement device measures the concentrations of a plurality of types of specific components.

13. The sample measurement system according to claim 11,

wherein the sample measurement system comprises a plurality of biosensors, and

the sample measurement device measures the concentration of one type of specific component.

14. A sample measurement method, in which a biosensor having an electrode is mounted to a measuring device for measuring the concentration of a specific component in a sample, voltage is applied to the electrode by the sample measurement device, and the concentration of the specific component in a sample deposited on the biosensor is measured, said sample measurement method comprising:

measuring a detection time, which is the length of time between the mounting of the biosensor to the measuring device and the deposition of the sample on the biosensor;

changing a set value for measuring the concentration of the specific component, according to the detection time; and

measuring the concentration of the specific component on the basis of the set value.

15. The sample measurement method according to claim 14,

wherein the set value is a measurement time for measuring the concentration of the specific component.

16. The sample measurement method according to claim 15,

wherein, in said changing the set value, the shorter is the detection time, the more the measurement time is extended.

17. The sample measurement method according to claim 14,

wherein the set value is a value of the voltage applied to the electrode.

18. The sample measurement method according to claim 14,

wherein said changing the set value further includes:

determining whether or not the detection time is within a specified length of time, and

changing the set value when it is determined that the detection time is within the specified length of time.

19. The sample measurement method according to claim 14,

further comprising measuring an environment temperature,

wherein the set value is changed according to the environment temperature in said changing the set value.

20. The sample measurement method according to claim 14,

further comprising calculating a hematocrit value,

wherein, in said changing the set value, the set value is changed according to the hematocrit value calculated in said calculating the hematocrit value.

21. The sample measurement method according to claim 14,

wherein changing the set value comprises choosing from a plurality of set values, and the plurality of set values consist of a measurement time for measuring the concentration of the specific component, and a value of the voltage applied to the electrode.

22. The sample measurement method according to claim 14,

further comprising setting the set value according to a type of sample.