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Apparatus and method for controlling insulin infusion with state variable feedback

  • US 8,348,886 B2
  • Filed: 05/01/2009
  • Issued: 01/08/2013
  • Est. Priority Date: 06/03/1999
  • Status: Expired due to Term
First Claim
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1. An apparatus for infusing a fluid into a body of a user, the apparatus comprising:

  • a housing;

    a pump inside the housing for delivering a fluid into the body of the user; and

    at least one controller to control delivery of the fluid from the housing by the pump,wherein the at least one controller;

    controls delivery of a basal amount of fluid to the body of the user at a predetermined basal rate;

    determines a bolus amount of fluid to be delivered to the body of the user;

    determines at least one state variable including a state variable for each of subcutaneous insulin concentration, plasma insulin concentration, and insulin effect;

    determines, based on the at least one state variable, an additional amount of fluid to be delivered to the body of the user with the bolus amount of fluid;

    controls delivery of the determined bolus amount of fluid and the determined additional amount of fluid to the user; and

    reduces the basal rate by the additional amount of fluid delivered with the bolus amount of fluid.

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