Electrochemical cell
First Claim
1. A sensor for the detection of glucose in a sample of blood, the sensor comprising:
- at least two conducting layers, wherein one of said conducting layers comprises a working electrode, said electrode is in contact with a reagent layer comprising a glucose specific enzyme; and
at least one insulating layer, wherein said insulating layer is interposed between said at least two conducting layers, and wherein said reagent layer is interposed between the working electrode and the insulating layer; and
a passage of uniform diameter extending from a first side of the sensor to a second side of the sensor opposite the first side, the passage being formed through each of said at least two conducting layers and said insulating layer.
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Accused Products
Abstract
An electrochemical cell for detection and quantification of analytes in a liquid sample, particularly a liquid sample having a small volume. In a preferred embodiment, the electrochemical cell comprises an assembly of conducting layers and insulating layers. The electrochemical cell can be formed by depositing conducting materials and insulating materials in alternating layers on an insulating substrate. It is preferred that the layer furthest from the insulating substrate be an insulating layer to minimize the damage of the conducting layers during handling of the electrochemical cell. In another embodiment, the assembly of conducting layers and insulating layers can be formed on both major surfaces of the insulating substrate. The assembly can comprise at least one working electrode and at least one other electrode, e.g., a dual-purpose reference/counter electrode.
15 Citations
24 Claims
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1. A sensor for the detection of glucose in a sample of blood, the sensor comprising:
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at least two conducting layers, wherein one of said conducting layers comprises a working electrode, said electrode is in contact with a reagent layer comprising a glucose specific enzyme; and at least one insulating layer, wherein said insulating layer is interposed between said at least two conducting layers, and wherein said reagent layer is interposed between the working electrode and the insulating layer; and a passage of uniform diameter extending from a first side of the sensor to a second side of the sensor opposite the first side, the passage being formed through each of said at least two conducting layers and said insulating layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A sensor for the detection of glucose in a blood sample, the sensor comprising:
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at least two conducting layers, wherein one of said conducting layers comprises a working electrode, said working electrode is in contact with a reagent layer comprising a glucose specific enzyme; and first, second, and third insulating layers, wherein said first insulating layer is interposed between said at least two conducting layers, wherein said reagent layer is interposed between the working electrode and the first insulating layer; and a passage of uniform diameter extending from a first side of the sensor to a second side of the sensor opposite the first side, the passage being formed through each of said at least two conducting layers and said insulating layers. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
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17. A sensor for the detection of glucose in a blood sample, the sensor comprising:
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an insulating substrate having a plurality of layers thereon, said layers comprising; at least two conducting layers, wherein one of said conducting layers comprises a working electrode, said working electrode is in contact with a reagent layer comprising a glucose specific enzyme; and first and second insulating layers, wherein said first insulating layer is interposed between said at least two conducting layers and wherein said reagent layer is interposed between the working electrode and the first insulating layer; and a passage of uniform diameter extending from a first side of the sensor to a second side of the sensor opposite the first side, the passage being formed through each of said at least two conducting layers and said insulating substrate. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24)
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Specification