Biosensor

• US 8,354,271 B2
• Filed: 07/08/2008
• Issued: 01/15/2013
• Est. Priority Date: 07/11/2007
• Status: Expired due to Fees

• Current Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Original Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Inventors: Takahashi, Makoto, Nakatani, Masaya, Ushio, Hiroshi
• Primary Examiner(s): Ball, J. Christopher
• Application Number:
  US12/668,538
• Publication Number:
  US 20100170790A1
• Time in Patent Office: 1,652 Days
• Field of Search: 20440301-40303, 205/777.5, 435/29, 435/63, 435/287.1, 435/287.3, 435/285.2, 435/288.5, 600/345, 600/900, 600/902, 422/98, 216/17, 216/41, 216/56, 216/58, 438/733, 438/734, 250/306, 250/307
• US Class Current: 435/287.3
• CPC Class Codes: C12M 23/12 Well or multiwell plates C12M25/04 takes precedence
• CPC Class Codes: C12M 23/20 Material Coatings immunocoatings C12M25/00
• CPC Class Codes: C12M 29/20 Degassing; Venting; Bubble traps means for collection or storage of gas C12M23/36; gas collection apparatus for laboratory use B01L5/02
• CPC Class Codes: G01N 33/48728 Investigating individual cells, e.g. by patch clamp, voltage clamp investigating individual particles in general G01N15/10

Abstract

A sensor includes a diaphragm having a through-hole (1), and includes a frame supporting a diaphragm and having a cavity. Kerfs are formed in a frame so as to extend from an end surface of the frame, and the wall surfaces of the kerfs are made hydrophilic. This structure can suppress the occurrence of bubbles in the vicinity of the through-hole, and efficiently remove the remaining bubbles. As a result, the bubbles adhering to the vicinity of the through-hole can be removed, and the measuring reliability of the sensor can be improved.

Claims

1. A biosensor comprising:

a diaphragm having a specimen holder; and

a frame supporting the diaphragm and having a cavity,

wherein a kerf is formed in the frame so as to have a dimension extending from the diaphragm to an end surface of the frame, the end surface being external to the cavity, and wall surfaces of the kerf are made hydrophilic.

2. The biosensor of claim 1, wherein the kerf is one of a plurality of kerfs formed in a radial configuration.

3. The biosensor of claim 2, wherein at least two of the kerfs have different widths.

4. The biosensor of claim 2, wherein the kerfs are formed so as not to form a wall surface in an inner circumferential part of the frame.

5. The biosensor of claim 1, wherein a width of the kerf is increased from an outer circumferential part to an inner circumferential part of the frame.

6. The biosensor of claim 1, wherein a bottom surface of the kerf is flush with the diaphragm.

7. The biosensor of claim 1, wherein a bottom surface of the kerf is inclined with respect to the diaphragm.

8. A biosensor comprising:

a diaphragm having a specimen holder; and

a frame supporting the diaphragm and having a cavity,

wherein a plurality of kerfs are formed in the frame so as to extend from an end surface of the frame,

the plurality of kerfs are formed so as not to form a wall surface in an inner circumferential part of the frame,

and wall surfaces of the kerfs are made hydrophilic.