Method of controlling a release of a material carried by ultrasound sensitive particles
First Claim
1. A method of controlling release of materials carried by ultrasound sensitive particles, the method comprising:
- irradiating a plurality of sub-groups of ultrasound sensitive particles with an ultrasonic pulse having an acoustic property selected so as to interact with ultrasound sensitive particles within one sub-group of the plurality of sub-groups, and thus causing release of material carried by the ultrasound sensitive particles of the one sub-group, while avoiding release of material carried by ultrasound sensitive particles within at least one other sub-group of the plurality of sub-groups,wherein the ultrasound sensitive particles within the one sub-group have an acoustic activation property different from a corresponding acoustic activation property of the ultrasound sensitive particles within the at least one other sub-group, causing each respective sub-group to interact independently with the ultrasonic pulse.
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Abstract
This invention relates to a method and an apparatus of controlling a release of a material carried by ultrasound sensitive particles, the release being caused by irradiating the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles and thus causing the release of the material. The ultrasound sensitive particles comprise sub-groups of ultrasound sensitive particles, the ultrasound sensitive particles within the same sub-group having their respective acoustic property causing each respective sub-group to interact independently with the sound wave.
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Citations
20 Claims
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1. A method of controlling release of materials carried by ultrasound sensitive particles, the method comprising:
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irradiating a plurality of sub-groups of ultrasound sensitive particles with an ultrasonic pulse having an acoustic property selected so as to interact with ultrasound sensitive particles within one sub-group of the plurality of sub-groups, and thus causing release of material carried by the ultrasound sensitive particles of the one sub-group, while avoiding release of material carried by ultrasound sensitive particles within at least one other sub-group of the plurality of sub-groups, wherein the ultrasound sensitive particles within the one sub-group have an acoustic activation property different from a corresponding acoustic activation property of the ultrasound sensitive particles within the at least one other sub-group, causing each respective sub-group to interact independently with the ultrasonic pulse. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. An apparatus for controlling a release of a material carried by ultrasound sensitive particles included in a plurality of sub-groups, the apparatus comprising:
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a control unit adapted to provide a control signal; and an ultrasound transducer coupled to the control unit and adapted to irradiate, in response to the control signal from the control unit, the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles in at least one sub-group and thus causing release of material carried by the ultrasound sensitive particles in the at least one of sub-group, while not causing release of material carried by the ultrasound sensitive particles in at least one other sub-group, wherein the ultrasound sensitive particles in each of the sub-groups have the same acoustic activation property, different from an acoustic activation property of the ultrasound sensitive particles in at least one other sub-group. - View Dependent Claims (15, 16)
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17. A delivery agent responsive to irradiation by an ultrasonic pulse, the delivery agent comprising:
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a plurality of first ultrasound sensitive particles in a first sub-group of a plurality of sub-groups in the delivery agent, each of the first ultrasound sensitive particles carrying material and having a common first acoustic property; and a plurality of second ultrasound sensitive particles in a second sub-group of the plurality of sub-groups in the delivery agent, each of the second ultrasound sensitive particles carrying material and having a common second acoustic property that is different from the first acoustic property, wherein release of the material carried by the first ultrasound sensitive particles or the second ultrasound sensitive particles is controllable by selection of an acoustic property of the ultrasonic pulse with which one of the first acoustic property of the first ultrasound sensitive particles and the second acoustic property of the second ultrasound sensitive particles interacts. - View Dependent Claims (18, 19, 20)
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Specification