Microneedles, microneedle arrays, and systems and methods relating to same
First Claim
1. A microneedle device, comprisinga first layer formed into the shape of a microneedle and comprising a first material suitable for piercing tissue,a continuous second layer disposed on and internal to the first layer and capable of acting as an electrical insulator, anda continuous third layer disposed on and internal to the second layer and capable of conducting electrical charge,wherein said microneedle has a length of between about 10 microns and 1 mm and permits passage of fluid and/or solid materials through the microneedle, andwherein the second layer is continuously disposed over the entire first layer.
4 Assignments
0 Petitions
Accused Products
Abstract
The microneedle devices disclosed herein in some embodiments include a substrate; one or more microneedles; and, optionally, a reservoir for delivery of drugs or collection of analyte, as well as pump(s), sensor(s), and/or microprocessor(s) to control the interaction of the foregoing.
-
Citations
30 Claims
-
1. A microneedle device, comprising
a first layer formed into the shape of a microneedle and comprising a first material suitable for piercing tissue, a continuous second layer disposed on and internal to the first layer and capable of acting as an electrical insulator, and a continuous third layer disposed on and internal to the second layer and capable of conducting electrical charge, wherein said microneedle has a length of between about 10 microns and 1 mm and permits passage of fluid and/or solid materials through the microneedle, and wherein the second layer is continuously disposed over the entire first layer.
-
20. A method for transporting a second material into or across a biological barrier, comprising
delivering the second material with a microneedle device comprising a first layer formed into the shape of a microneedle and comprising a first material suitable for piercing tissue, a continuous second layer disposed on and internal to the first layer and capable of acting as an electrical insulator, and a continuous third layer disposed on and internal to the second layer and capable of conducting electrical charge, wherein said microneedle has a length of between about 10 microns and 1 mm and permits passage of fluid and/or solid materials through the microneedle, and wherein the second layer is continuously disposed over the entire first layer.
Specification