Micrornas differentially expressed in cervical cancer and uses thereof
First Claim
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1. A method for identifying a biomarker indicative of cervical precancer or cancer in a patient comprising measuring an expression profile of one or more miRNAs in a cervical sample from a patient suspected of having a precancerous or cancerous cervical condition and identifying the patient as having a biomarker indicative of cervical precancer or cancer after measuring a decrease in hsa-miR-1 (SEQ ID NO:
- 87) expression compared to an expression profile of a normal cervical sample.
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Abstract
The present invention concerns methods and compositions for identifying a miRNA profile for a particular condition, such as cervical disease, and using the profile in assessing the condition of a patient.
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13 Claims
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1. A method for identifying a biomarker indicative of cervical precancer or cancer in a patient comprising measuring an expression profile of one or more miRNAs in a cervical sample from a patient suspected of having a precancerous or cancerous cervical condition and identifying the patient as having a biomarker indicative of cervical precancer or cancer after measuring a decrease in hsa-miR-1 (SEQ ID NO:
- 87) expression compared to an expression profile of a normal cervical sample.
- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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