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Non-invasive glucose meter

  • US 8,364,219 B2
  • Filed: 12/02/2009
  • Issued: 01/29/2013
  • Est. Priority Date: 08/02/2001
  • Status: Active Grant
First Claim
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1. A method of determining the concentration of a substance in an eye, the method comprising:

  • providing a nearly parallel measurement light beam having a first wavelength at which the substance has a non-zero first absorption coefficient;

    providing a nearly parallel reference light beam having a second wavelength at which the substance has a second absorption coefficient which is substantially equal to zero;

    irradiating the retina of the eye with the measurement light beam;

    irradiating the retina of the eye with the reference light beam;

    reflecting at least a portion of the measurement light beam from the retina, thereby producing a retro-reflected measurement light beam having the first wavelength;

    reflecting at least a portion of the reference light beam from the retina, thereby producing a retro-reflected reference light beam having the second wavelength;

    generating a measurement signal in response to the retro-reflected measurement light beam;

    generating a reference signal in response to the retro-reflected reference light beam; and

    determining the concentration of the substance in the eye in response to the measurement signal and the reference signal.

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