Integrated biosensor and stimulation system for diagnosis and therapy
First Claim
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1. A method for predicting therapeutic strategy in a biological system comprising the steps of:
- accessing by a controller a data storage, wherein said controller is located within an implantable bionetwork biosensor apparatus comprising a sensor unit comprising a positioning chip and a biosensor platform;
the controller comprising a network, a systems biology platform, a data storage, and a wireless communication unit;
a therapeutic unit comprising a therapeutic manufacture, therapeutic reservoirs, and a sensor manufacture; and
a power module coupled to the sensor unit, the controller, and the therapeutic unit;
executing from one or more software tools stored within said data storage which represents one or more biological processes and molecular interactions as mathematical models;
accessing by the controller the systems biology platform via the network to said stored software tools, wherein the systems biology platform comprises a computational biology simulator using reconfigurable emulation logic devices that access genomics database, transcriptomics database, proteomics database, metabolomics database, pharmacogenomics database, pharmacokinetics database, disease database and drug database;
executing by the controller a set of simulations using said reconfigurable emulation logic devices pertaining to administration of a drug; and
causing by the controller to generate a simulation report to predict outcome of the interactions of the biological system with the drug, thereby aiding in target discovery and validation.
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Abstract
BioMEMS/NEMS appliance biologically monitors an individual, using biosensors to detect cellular components. Data is simulated or analyzed using systems-biology software, which provides diagnostic or therapeutic guidance.
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Citations
1 Claim
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1. A method for predicting therapeutic strategy in a biological system comprising the steps of:
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accessing by a controller a data storage, wherein said controller is located within an implantable bionetwork biosensor apparatus comprising a sensor unit comprising a positioning chip and a biosensor platform;
the controller comprising a network, a systems biology platform, a data storage, and a wireless communication unit;
a therapeutic unit comprising a therapeutic manufacture, therapeutic reservoirs, and a sensor manufacture; and
a power module coupled to the sensor unit, the controller, and the therapeutic unit;executing from one or more software tools stored within said data storage which represents one or more biological processes and molecular interactions as mathematical models; accessing by the controller the systems biology platform via the network to said stored software tools, wherein the systems biology platform comprises a computational biology simulator using reconfigurable emulation logic devices that access genomics database, transcriptomics database, proteomics database, metabolomics database, pharmacogenomics database, pharmacokinetics database, disease database and drug database; executing by the controller a set of simulations using said reconfigurable emulation logic devices pertaining to administration of a drug; and causing by the controller to generate a simulation report to predict outcome of the interactions of the biological system with the drug, thereby aiding in target discovery and validation.
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Specification