Selective resonance of chemical structures

• US 8,364,412 B2
• Filed: 11/19/2008
• Issued: 01/29/2013
• Est. Priority Date: 07/21/2005
• Status: Active Grant

• Current Assignee: Enterprise Science Fund, LLC (Intellectual Ventures LLC)
• Original Assignee: The Invention Science Fund I, L.L.C. (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Jung, Edward K. Y., Myhrvold, Nathan P., Wood, Lowell L. Jr.
• Primary Examiner(s): Lin, Jerry
• Application Number:
  US12/313,418
• Publication Number:
  US 20090071817A1
• Time in Patent Office: 1,532 Days
• Field of Search: 702/19
• US Class Current: 702/19
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61K 41/0004 Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
• CPC Class Codes: A61N 5/00 Radiation therapy ultrasound therapy A61N7/00; devices or apparatus applicable to both therapy and diagnosis A61B6/00
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent

Abstract

Chemical compositions may be selectively or preferentially excited by the application of scores comprising a series of differing energy inputs. The set of excitation energies includes frequencies selected to resonate at least two different structures of the plurality of resonant structures, where the set, applied together, causes a chemical change in the composition, but any one of the excitation energies, applied alone, would not cause the chemical change in the composition.

Claims

1. A method of exciting a composition including a plurality of resonant structures, each resonant structure having a resonant frequency, the method comprising:

selecting a set of excitation energies; and

applying the set of excitation energies to the composition, wherein;

each of the excitation energies has a frequency matching the resonant frequency of at least one of the resonant structures of the plurality, wherein the set of excitation energies includes frequencies selected to resonate at least two different structures of the plurality of resonant structures;

the set of excitation energies, applied together, causes a chemical change in the composition; and

any one of the excitation energies, applied alone, would not cause the chemical change in the composition.

2. The method of claim 1, wherein the frequency is a modulation frequency.

3. The method of claim 1, wherein the excitation energies are applied simultaneously.

4. The method of claim 1, wherein the excitation energies are applied sequentially.

5. The method of claim 1, wherein the excitation energies are applied in a temporally overlapping fashion.

6. The method of claim 1, wherein the chemical change in the composition comprises an effect selected from the group consisting of:

breaking a bond between two atoms of the composition; and

changing a kinetic parameter of a reaction involving the composition.

7. The method of claim 1, wherein the composition is a biomolecule.

8. The method of claim 7, wherein the biomolecule is a protein or a nucleotide.

9. The method of claim 1, wherein the composition is a crystal.

10. The method of claim 1, wherein the composition is a complex of molecules.

11. The method of claim 1, wherein the plurality of resonant structures comprises a longitudinal vibrational mode of a bond.

12. The method of claim 1, wherein the plurality of resonant structures comprises a bending mode of two bonds to an atom.

13. The method of claim 1, wherein the plurality of resonant structures comprises a squashing mode of a plurality of bonds.

14. The method of claim 1, wherein the excitation energies are electromagnetic beams.

15. The method of claim 14, wherein each electromagnetic beam has at least one characteristic selected from the group consisting of:

a selected set of frequencies;

a selected set of phases;

a selected set of amplitudes;

a selected temporal profile;

a selected set of polarizations; and

a selected direction.

16. The method of claim 15, wherein the selected set of frequencies is approximately monochromatic.

17. The method of claim 15, wherein the selected set of frequencies comprises a plurality of local maxima.

18. The method of claim 15, wherein at least one of the electromagnetic beams is polarized.

19. The method of claim 14, wherein at least one of the electromagnetic beams is an infrared beam.

20. The method of claim 14, wherein at least one of the electromagnetic beams is amplitude modulated.

21. The method of claim 14, wherein at least one of the electromagnetic beams is frequency modulated.

22. The method of claim 14, further comprising scanning at least one of the electromagnetic beams.

23. The method of claim 14, wherein at least two of the electromagnetic beams intersect at a target location.

24. The method of claim 1, further comprising applying a field to the composition, wherein the field acts to preferentially orient at least one resonant structure.

25. The method of claim 1, wherein:

the plurality of resonant structures are in an arrangement having two end resonant structures and a center resonant structure; and

the set of excitation energies is applied in a sequence beginning from the excitation energies having frequencies matching the two end resonant structures and progressing towards the excitation energy having the frequency matching the center resonant structure.

26. The method of claim 1, wherein the set of excitation energies comprises at least 4 excitation energies.

27. The method of claim 1, wherein the set of excitation energies comprises at least 10 excitation energies.

28. The method of claim 1, wherein the set of excitation energies comprises at least 36 excitation energies.

29. The method of claim 15, wherein the selected set of frequencies is approximately Gaussian.

30. The method of claim 15, wherein at least one of the electromagnetic beams is coherent.

31. The method of claim 15, wherein at least one of the electromagnetic beams is incoherent.

32. The method of claim 15, wherein the selected set of frequencies comprises at least two frequencies, and wherein the at least two frequencies have differing amplitudes.

33. The method of claim 15, wherein the temporal profile is characterized by a selected beam duration.

34. The method of claim 15, wherein the temporal profile is characterized by a selected change in frequency, phase, amplitude, polarization, or direction during a selected time interval.

35. The method of claim 14, wherein at least two of the electromagnetic beams differ in frequency, phase, amplitude, temporal profile, polarization or orientation.

36. The method of claim 24, wherein the field is selected from the group consisting of an electric field, a magnetic field, an electromagnetic field, a mechanical stress, a mechanical strain, a lowered or elevated temperature, a lowered or elevated pressure, a phase change, an adsorbing surface, a catalyst, an excitation energy, and combinations thereof.

37. The method of claim 26, wherein the composition undergoes a physical effect upon application of the excitation energy having the frequency matching the center resonant structure.

38. The method of claim 26, wherein resonance of the center structure breaks a predetermined bond between two atoms of the composition.

39. The method of claim 26, wherein the set of excitation energies is applied in a temporally overlapping sequence.