Intraocular pressure regulating device

• US 8,366,653 B2
• Filed: 03/13/2008
• Issued: 02/05/2013
• Est. Priority Date: 03/13/2007
• Status: Active Grant

• Current Assignee: University of Rochester
• Original Assignee: University of Rochester
• Inventors: Abushagur, Mustafa A. G., Shareef, Shakeel R.
• Primary Examiner(s): Zalukaeva, Tatyana
• Assistant Examiner(s): KLEIN, BENJAMIN JACOB
• Application Number:
  US12/531,293
• Publication Number:
  US 20110046728A1
• Time in Patent Office: 1,790 Days
• Field of Search: 604/9, 623 639- 642, 623/6.51
• US Class Current: 604/9
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002

Abstract

Systems and methods are described for implanting a device in a mammalian eye to raise intraocular pressure. In some embodiments, the device (54) includes an arcuate body that, when implanted, obstructs aqueous humor outflow from the anterior chamber (38) of the eye.

Claims

1. A method, of elevating intraocular pressure in a mammalian eye, comprising:

inserting a device, comprising an arcuate body, along an arc of at least 90 degrees in the iridocorneal angle of the eye and in contact with the trabecular meshwork such that a placement of the device along the arc impedes outflow of aqueous humor through the trabecular meshwork, thereby increasing intraocular pressure within the eye.

2. The method of claim 1, further comprising adjusting an amount of obstruction of the outflow.

3. The method of claim 1, further comprising selecting a size of the device, prior to the inserting, using ocular imaging.

4. The method of claim 1, further comprising modeling glaucoma using the device after the inserting of the device in the eye.

5. The method of claim 1, further comprising treating hypotony of the eye using the device by the inserting of the device in the eye.

6. The method of claim 1, wherein the device comprises at least one aperture, and the device is inserted such that aqueous humor passes through the at least one aperture in the device.

7. The method of claim 1, wherein the device comprises pores, and the device is inserted such that aqueous humor passes through the pores in the device.

8. The method of claim 1, further comprising inducing ischemia in the trabecular meshwork.

9. The method of claim 1, wherein the device is inserted along an arc of at least 180 degrees in the iridocorneal angle of the eye.

10. The method of claim 1, wherein the device is inserted along an arc of at least 270 degrees in the iridocorneal angle of the eye.