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Integrated biosensor and simulation system for diagnosis and therapy

  • US 8,370,070 B2
  • Filed: 10/24/2008
  • Issued: 02/05/2013
  • Est. Priority Date: 08/22/2003
  • Status: Active Grant
First Claim
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1. Integrated biosensor platform comprising:

  • a multifunctional array comprising a microelectronic array of biosensor electrodes in which at least one microelectrode sensor cavity generates controllable electric current or voltage for drawing probes, samples, or reagents to locations on a sensor platform thereby allowing faster, controlled hybridization or analysis thereof, whereby the multifunctional array serves as programmable or logical interconnect for coupling or switching various sensor devices, and interacts with samples and detection system to interpret samples into data for automated analysis by a systems-biology platform that electronically configures the microelectronic array to couple or interconnect selectively according to simulation or modeling to access actual host condition via one or more biosensor signals, such signals being compared by the systems-biology platform against a simulation model or other software prediction.

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