Molecular recognition of materials

• US 8,372,949 B2
• Filed: 07/24/2007
• Issued: 02/12/2013
• Est. Priority Date: 06/05/2001
• Status: Expired due to Fees

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Belcher, Angela M.
• Primary Examiner(s): WESSENDORF, TERESA D
• Application Number:
  US11/782,038
• Publication Number:
  US 20080242552A1
• Time in Patent Office: 2,030 Days
• Field of Search: 530/327, 530/321, 435/320.1, 506/14, 506/18, 506/21, 506/22
• US Class Current: 530/327
• CPC Class Codes: G01N 33/543 with an insoluble carrier for immobilising immunochemicals
• CPC Class Codes: G01N 33/68 involving proteins, peptides or amino acids involving lipoproteins G01N33/92
• CPC Class Codes: G01N 33/6803 General methods of protein analysis not limited to specific proteins or families of proteins

Abstract

The present invention includes methods for selective binding of inorganic materials and the compositions that made up of the selecting agent and the target materials. One form of the present invention is a method for selecting crystal-binding peptides with binding specificity including the steps of contacting one or more amino acid oligomers with one or more single-crystals of a semiconductor material so that the oligomers may bind to the crystal and eluting the bound amino acid oligomers from the single-crystals.

Claims

1. An isolated peptide sequence that selectively binds to a crystalline face of a target crystal, wherein the peptide sequence is selected from the group consisting of SEQ. ID. Nos. 1 to 11, which has been isolated from phage display library or a combinatorial library.

2. The isolated peptide sequence according to claim 1, wherein the target crystal is a single crystal.

3. The isolated peptide sequence according to claim 1, wherein the target crystal is an inorganic crystal.

4. The isolated peptide sequence according to claim 1, wherein the target crystal is a semiconductor crystal.

5. The isolated peptide sequence according to claim 1, wherein the target crystal is a Group III-V semiconductor crystal or a Group II-VI semiconductor crystal.

6. The isolated peptide sequence according to claim 1, wherein the target crystal is a nanoparticle.

7. The isolated peptide sequence according to claim 1, wherein the target crystal is gallium arsenide, indium phosphide, gallium nitride, zinc sulfide, cadmium sulfide, aluminum arsenide, gallium stibinide, aluminum gallium arsenide, aluminum stibinide, aluminum arsenide, cadmium selenide, zinc selenide, cadmium telluride, zinc selenide, indium arsenide, silicon, FePd, cobalt, manganese, lithium niobate, iron oxide, silica or calcium carbonate.

8. The composition according to claim 1, wherein the peptide binding sequence is bound to a nanoparticle, a surface, or a patterned surface.