Patient immobilization and repositioning method and apparatus used in conjunction with charged particle cancer therapy

• US 8,373,143 B2
• Filed: 12/12/2009
• Issued: 02/12/2013
• Est. Priority Date: 05/22/2008
• Status: Active Grant

• Current Assignee: Andrey Vladimirovich Balakin, Pavel Vladimirovich Balakin
• Original Assignee: Vladimir Balakin
• Inventors: Balakin, Vladimir
• Primary Examiner(s): Vanore, David A
• Application Number:
  US12/636,725
• Publication Number:
  US 20100091948A1
• Time in Patent Office: 1,158 Days
• Field of Search: 250/492.1, 250/492.2, 250/492.22, 600/1, 600/7, 600/11, 600/38
• US Class Current: 250/492.2
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 2005/1097 Means for immobilizing the patient
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: H05H 13/04 Synchrotrons
• CPC Class Codes: H05H 7/10 Arrangements for ejecting particles from orbits

Abstract

This invention relates generally to treatment of solid cancers. More particularly, the invention relates to a computer controlled patient positioning, immobilization, and repositioning method and apparatus used in conjunction with multi-field charged particle cancer therapy coordinated with patient respiration patterns and further in combination with charged particle beam injection, acceleration, extraction, and/or targeting methods and apparatus.

Claims

1. An apparatus for positioning a tumor of a patient for treatment with charged particles, comprising:

a computer controlled patient positioning system, comprising an upper body support, wherein said upper body support comprises a semi-upright patient support surface, said computer controlled positioning system configured to use recorded patient position information in repositioning the patient when the patient sits down after a departure; and

a charged particle irradiation system comprising a charged particle beam path, said charged particle beam path passing within about six inches of said semi-upright patient support surface.

2. The apparatus of claim 1, wherein the charged particles travel along said charged particle beam path to the tumor of the patient.

3. The apparatus of claim 1, wherein said semi-upright patient support surface is reclined from a vertical axis by less than about sixty-five degrees.

4. The apparatus of claim 1, wherein said patient positioning system further comprises:

at least three of;

a motorized torso positioning system;

a motorized head positioning system;

a motorized arm positioning system;

a motorized back positioning system; and

a motorized foot positioning system; and

computer memory for recalling individualized motor positions for any of;

said motorized torso positioning system;

said motorized head positioning system;

said motorized arm positioning system;

said motorized back positioning system; and

said motorized foot positioning system.

5. The apparatus of claim 4, wherein said charged particle irradiation system comprises control of:

beam energy; and

beam intensity,

wherein said patient positioning system further comprises a rotatable platform,

wherein said charged particle beam path passes above a portion of said rotatable platform,

wherein said rotatable platform comprises;

a lower support structure, said lower support structure holding a portion of said patient positioning system;

an upper support structure, said upper support structure holding;

a camera; and

a video screen,

wherein said patient positioning system is configured to provide respiration instructions on said video screen.

6. The apparatus of claim 1, said charged particle irradiation system comprising:

a negative ion source, said negative ion source producing negative ions;

an ion beam focusing lens focusing the negative ions;

a converting foil, said converting foil converting the negative ions into the charged particles; and

a synchrotron, said synchrotron comprising;

a center;

straight sections; and

turning sections,

wherein said charged particle beam path runs;

about said center;

through said straight sections; and

through said turning sections,

wherein each of said turning sections comprises a plurality of bending magnets,

wherein said circulation beam path comprises a length of less than sixty meters, and

wherein a number of said straight sections equals a number of said turning sections.

7. The apparatus of claim 1, said charged particle irradiation system further comprising a synchrotron, said synchrotron having a center, said apparatus comprising:

an extraction material;

at least a one kilovolt direct current field applied across a pair of extraction blades; and

a deflector,

wherein the charged particles pass through said extraction material resulting in a reduced energy charged particle beam,

wherein the reduced energy charged particle beam passes between said pair of extraction blades, and

wherein the direct current field redirects the reduced energy charged particle beam through said deflector,

wherein said deflector yields extracted charged particles.

8. The apparatus of claim 1, further comprising:

an X-ray generation source located within forty millimeters of the charged particle beam path, wherein said X-ray source maintains a single static position;

(1) during use of said X-ray source and (2) during tumor treatment with the charged particles, wherein X-rays emitted from said X-ray source run substantially in parallel with the charged particle beam path, wherein said X-ray generation source comprises a tungsten anode; and

a treatment control delivery system integrating use of said X-ray generation source within thirty seconds of subsequent use of said charged particle irradiation system.

9. The apparatus of claim 1, further comprising:

a respiration sensor configured to generate a respiration signal, said respiration signal corresponding to a respiration cycle of the patient;

a rotatable platform holding the patient,

wherein said rotatable platform rotates through at least one hundred eighty degrees during an irradiation period of the patient,

wherein an X-ray generation source is timed using said respiration signal to produce X-ray images at a set point in the respiration cycle,

wherein said X-ray images represent greater than ten rotation positions of said rotatable platform, and

wherein the X-ray images combine to form a three-dimensional image of the tumor,

wherein said charged particle irradiation system further comprises a synchrotron comprising multi-axis control, said multi-axis control comprising control of;

an energy; and

an intensity,

wherein said control of said energy and said control of said intensity occurs during extraction.

10. The apparatus of claim 1, wherein said charged particle irradiation system further comprises:

a synchrotron; and

a rotatable platform,

wherein said rotatable platform supports said patient positioning system;

wherein said charged particle beam path runs through said synchrotron and terminates above said rotatable platform;

wherein said rotatable platform rotates at least ninety degrees during an irradiation period, and

wherein said rotatable platform rotates to at least five irradiation positions during said irradiation period.

11. A method for positioning a tumor of a patient for treatment with charged particles, comprising the steps of:

positioning the patient with a computer controlled patient positioning system configured to use recorded patient position information in repositioning the patient when the patient sits down after a departure, said patient positioning system comprising an upper body support, wherein said upper body support comprises a semi-upright patient support surface; and

irradiating the tumor of the patient with the charged particles from a charged particle system, said charged particle system comprising a charged particle beam path, said charge particle beam path passing within about six inches of said semi-upright patient support surface,

wherein the charged particles travel along said charged particle beam path to the tumor of the patient.

12. The method of claim 11, wherein said semi-upright patient support surface comprises a reclined position from a vertical axis of less than about sixty-five degrees.

13. The method of claim 11, further comprising the steps of:

said patient positioning system semi-restraining movement of the patient using at least three of;

a motorized torso positioning system;

a motorized head positioning system;

a motorized arm positioning system;

a motorized back positioning system; and

a motorized foot positioning system; and

recalling from a computer memory individualized motor positions for any of;

said motorized torso positioning system;

said motorized head positioning system;

said motorized arm positioning system;

said motorized back positioning system; and

said motorized foot positioning system.

14. The method of claim 13, further comprising the steps of:

after said step of positioning, collecting multi-field images of the tumor in the patient;

developing a tumor irradiation plan;

repositioning the tumor using said patient positioning system; and

repeating said step of irradiating in at least four rotation positions.

15. The method of claim 11, further comprising the steps of:

varying intensity of the charged particles dependent upon efficiency of delivery of energy of the charged particles within the tumor versus delivery of energy of the charged particles to healthy tissue of the patient;

holding the patient with a rotatable platform, said rotatable platform holding at least a portion of said patient positioning system;

rotating the patient on said rotatable platform;

delivering the charged particles to the tumor of the patient from a synchrotron of said charged particle system during said step of rotating the patient;

distributing ingress energy of the charged particles to at least ten areas about the tumor;

generating a respiration signal with a respiration sensor, said respiration signal corresponding to a respiration cycle of the patient; and

timing delivery of the charged particles to the tumor at a set point in said respiration cycle using said respiration signal.

16. The method of claim 11, further comprising the step of:

controlling a magnetic field in a bending magnet of a synchrotron in said charged particle system, said bending magnet comprising;

a tapered iron based core adjacent a gap, said core comprising a surface polish of less than about ten microns roughness; and

a focusing geometry comprising;

a first cross-sectional distance of said iron based core forming an edge of said gap,

a second cross-sectional distance of said iron based core not in contact with said gap, wherein said second cross-sectional distance is at least fifty percent larger than said first cross-sectional distance, said first cross-sectional distance running parallel said second cross-sectional distance.

17. The method of claim 11, further comprising the steps of:

controlling an energy of the charged particle using an accelerator in said charged particle system, said accelerator comprising;

a set of at least ten coils;

a set of at least ten wire loops; and

a set of at least ten microcircuits, each of said microcircuits integrated to one of said loops, wherein each of said loops completes at least one turn about at least one of said coils; and

using a radio-frequency synthesizer, sending a low voltage signal to each of said microcircuits, each of said microcircuits amplifying said low voltage signal yielding an acceleration voltage.

18. The method of claim 11, further comprising the step of:

monitoring both a horizontal position of the charged particles and a vertical position of the charged particles in said charged particle beam path using a coating on a foil, said coating comprising a layer yielding a localized photonic signal when struck by the charged particles.

19. The method of claim 11, further comprising the step of:

increasing an intensity of the charged particles when targeting a distal portion of the tumor, wherein said distal portion of said tumor changes with rotation of the patient on a platform rotating to at least ten distinct rotational positions in a period of less than one minute during irradiation of the tumor by the charged particles, said platform holding the patient.