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Closed loop control system with safety parameters and methods

  • US 8,377,031 B2
  • Filed: 08/31/2008
  • Issued: 02/19/2013
  • Est. Priority Date: 10/23/2007
  • Status: Active Grant
First Claim
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1. A method, comprising:

  • monitoring, using one or more processors, a plurality of parameters associated with a closed loop control operation including continuously monitoring a physiological condition and an automatic administration of a medication, wherein the plurality of parameters monitored includes an analyte level;

    detecting an adverse condition associated with the monitored physiological condition or the automatic medication administration deviating from a predetermined safety level of medication delivery of the closed loop control operation;

    initiating a non-zero pre-programmed medication delivery rate when the adverse condition is detected, wherein the non-zero pre-programmed medication delivery rate is different than the automatic administration of medication and wherein the non-zero pre-programmed medication delivery rate is based on the predetermined safety level of medication delivery;

    estimating medication on board information based on the monitored administration of the medication and outputting a notification based on the estimated medication on board information;

    modifying the initiated non-zero pre-programmed medication delivery rate using the estimated medication on board information;

    determining an acceleration of a level of a monitored analyte change; and

    updating the medication delivery rate based on the determined acceleration of the level of the monitored analyte change.

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