Polymerizable surfactants and their use as device forming comonomers

• US 8,377,464 B2
• Filed: 02/27/2012
• Issued: 02/19/2013
• Est. Priority Date: 12/22/2004
• Status: Active Grant

• Current Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Original Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Inventors: Linhardt, Jeffrey G., Ammon, Daniel M. Jr., Salamone, Joseph C., Hook, Daniel J.
• Primary Examiner(s): ROGERS, JAMES WILLIAM
• Application Number:
  US13/405,604
• Publication Number:
  US 20120157565A1
• Time in Patent Office: 358 Days
• Field of Search: None
• US Class Current: 424/427
• CPC Class Codes: G02B 1/043 Contact lenses

Abstract

This invention describes the use of polymerizable surfactants as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.

Claims

1. An ophthalmic device comprising:

a polymerized comonomer mixture comprising at least one polymerizable surfactant selected from the group consisting of a poloxamer di(meth)acrylate, a reverse poloxamer di(meth)acrylate, a poloxamine di(meth)acrylate, a reverse poloxamine di(meth)acrylate and mixtures thereof, wherein the at least one polymerizable surfactant is present in the comonomer mixture prior to polymerization in an amount of about 0.1 to about 4.9 weight percent, and further wherein the ophthalmic device is a contact lens, an intraocular lens or a corneal implant, wherein the ophthalmic device has a water content of from about 20 to about 90 weight percent.

2. A hydrogel contact lens comprising:

a polymerized comonomer mixture comprising at least one polymerizable surfactant selected from the group consisting of a poloxamer di(meth)acrylate, a reverse poloxamer di(meth)acrylate, a poloxamine di(meth)acrylate, a reverse poloxamine di(meth)acrylate and mixtures thereof, wherein the at least one polymerizable surfactant is present in the comonomer mixture prior to polymerization in an amount of about 0.1 to about 4.9 weight percent, and further wherein the ophthalmic device is a contact lens, an intraocular lens or a conical implant, wherein the ophthalmic device has a modulus from about 20 g/mm² to about 150 g/mm².

3. A hydrogel contact lens comprising:

a polymerized comonomer mixture comprising at least one polymerizable surfactant selected from the group consisting of a poloxamer di(meth)acrylate, a reverse poloxamer di(meth)acrylate, a poloxamine di(meth)acrylate, a reverse poloxamine di(meth)acrylate and mixtures thereof, wherein the at least one polymerizable surfactant is present in the comonomer mixture prior to polymerization in an amount of about 0.1 to about 4.9 weight percent, and further wherein the ophthalmic device is a contact lens, an intraocular lens or a corneal implant, wherein the ophthalmic device has a modulus of from about 30 g/mm² to about 100 g/mm².