Non-invasive determination of characteristics of a sample

• US 8,382,668 B2
• Filed: 11/18/2009
• Issued: 02/26/2013
• Est. Priority Date: 06/21/2007
• Status: Active Grant

• Current Assignee: RF Science & Technology, Inc.
• Original Assignee: RF Science & Technology, Inc.
• Inventors: Harra, David James, Xu, Aiguo
• Primary Examiner(s): Natnithithadha, Navin
• Application Number:
  US12/621,483
• Publication Number:
  US 20100072386A1
• Time in Patent Office: 1,196 Days
• Field of Search: 600/365, 600/310, 600/316, 600/322, 600/309, 600/407
• US Class Current: 600/365
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/0507 using microwaves or terahertz waves
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance

Abstract

Systems and methods for non-invasively scanning and analyzing one or more characteristics of a sample utilizing electromagnetic radiation are described. More particularly, the systems and methods utilize an electromagnetic radiation source connected to a transmitter and an analyzer connected to a receiver. A sample to be analyzed is placed between the transmitter and receiver in a variety of different manners and a frequency sweep of electromagnetic radiation is transmitted through the sample to create a series of spectral data sets that are used to create one or more composite spectrograms, which are then analyzed to determine one or more characteristics of the sample. A magnetic field can alternatively be applied around the transmitter, receiver and sample to enhance some characteristic analysis applications. Samples include inert and living items, and the characteristics include a wide variety of different applications.

Claims

1. A method of registering and enrolling a sample in a sample scanning and analysis system including a storage system, comprising the steps of:

scanning said sample with a scanning apparatus, said scanning apparatus including a transmitter for transmitting a series of electromagnetic signals, each signal of said series of electromagnetic signals having a transmitted amplitude over a plurality of sample points within a range of frequencies, and a receiver for receiving said series of electromagnetic signals as said series of electromagnetic signals are reflected from or transmitted through said sample;

generating a series of spectral data sets representing at least a scanned amplitude of each signal of said series of electromagnetic signals over said plurality of sample points;

generating one or more composite spectrograms from said series of spectral data sets;

analyzing said composite spectrograms to identify a characteristic of said sample having a first variance that is minimized across said one or more composite spectrograms and a second variance that is maximally different from a plurality of characteristics corresponding to a plurality of other samples in said storage system; and

storing said characteristic in said storage system.

2. The method of claim 1, wherein said scanning step measures a real and an imaginary component of said series of electromagnetic signals transmitted and a real and an imaginary component of said series of electromagnetic signals received.

3. The method of claim 1, further comprising:

measuring real components and imaginary components of said series of electromagnetic signals received, wherein said real components represent purely resistive properties of said sample and wherein said imaginary components represent capacitive and inductive properties of said sample.

4. The method of claim 1, wherein each signal of said series of electromagnetic signals transmitted by said transmitter are within a range of frequencies between about 0.3 MHz and about 20.1 GHz.

5. The method of claim 1, wherein said sample is a human finger.

6. The method of claim 1, wherein said sample is a material.

7. The method of claim 1, wherein said sample is a liquid.

8. The method of claim 1, further comprising the step of building a profile of said sample in said storage system, said profile being derived from said characteristic.

9. A method of registering a sample in a sample scanning and analysis system including a storage system, comprising the steps of:

scanning said sample with a scanning apparatus at least once, said scanning apparatus including a transmitter for transmitting a series of electromagnetic signals, each signal of said series of electromagnetic signals having a transmitted amplitude over a plurality of sample points within a range of frequencies, and a receiver for receiving said series of electromagnetic signals as said series of electromagnetic signals are reflected from or transmitted through said sample;

generating a series of spectral data sets representing at least a scanned amplitude of each signal of said series of electromagnetic signals over said plurality of sample points;

generating one or more composite spectrograms from said series of spectral data sets;

analyzing said one or more composite spectrograms to identify a characteristic of said sample having a first variance that is minimized across said one or more composite spectrograms and a second variance that is maximally different from a plurality of characteristics corresponding to a plurality of other samples in said storage system; and

storing said characteristic in said storage system.

10. The method of claim 9, wherein said scanning step measures a real and an imaginary component of said series of electromagnetic signals transmitted and a real and an imaginary component of said series of electromagnetic signals received.

11. The method of claim 9, further comprising:

measuring real components and imaginary components of said series of electromagnetic signals received, wherein said real components represent purely resistive properties of said sample and wherein said imaginary components represent capacitive and inductive properties of said sample.

12. The method of claim 9, wherein each signal of said series of electromagnetic signals transmitted by said transmitter are within a range of frequencies between about 0.3 MHz and about 20.1 GHz.

13. The method of claim 9, wherein said sample is a human finger.

14. The method of claim 9, wherein said sample is a material.

15. The method of claim 9, wherein said sample is a liquid.

16. The method of claim 9, wherein said sample is scanned multiple times.

17. The method of claim 9, wherein said sample is only scanned once.

18. The method of claim 9, further comprising the step of building a profile of said sample in said storage system, said profile being derived from said characteristic.