Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides

• US 8,382,824 B2
• Filed: 10/03/2008
• Issued: 02/26/2013
• Est. Priority Date: 10/03/2008
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Inventors: Weber, Jan
• Primary Examiner(s): PELLEGRINO, BRIAN E
• Application Number:
  US12/245,456
• Publication Number:
  US 20100087910A1
• Time in Patent Office: 1,607 Days
• Field of Search: 623/1.15, 623/1.38, 623/1.46, 623/23.53, 623/23.56, 623/1.39, 623/1.42, 623/1.43, 623/1.34, 427/2.25
• US Class Current: 623/1.46
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: A61L 31/088 Other specific inorganic materials not covered by A61L31/084 or A61L31/086
• CPC Class Codes: A61L 31/148 Materials at least partially resorbable by the body

Abstract

A endoprosthesis includes a body comprising a plurality of interconnected struts. The body includes a bioerodible metal. At least a first strut of the plurality of interconnected struts includes a stripe on the surface of the first strut. The stripe including a nitride of the bioerodible metal, a fluoride of the bioerodible metal, or a combination thereof. The stripe runs along the length of the first strut. The stripe is part of a continuous network of stripes on struts adjacent to the first strut.

Claims

1. An endoprosthesis comprising:

a body comprising a plurality of interconnected struts, the body comprising a bioerodible metal, and

at least a first strut of the plurality of interconnected struts including a stripe on the surface of the first strut, the stripe comprising a nitride of the bioerodible metal, a fluoride of the bioerodible metal, or a combination thereof, the stripe running along the length of the first strut, the stripe having a width less than a width of the first strut and being bordered by non-nitrided-nor-fluorided regions of the strut, the stripe being part of a continuous network of stripes on struts adjacent to the first strut, wherein the bioerodible metal of the body has nano-crystal grains and a plurality of corrosion barrier layers in or between the nano-crystal grains throughout the body, the corrosion barrier layers comprising a metal nitride, a metal fluoride, or a combination thereof.

2. A medical implant comprising a body that includes a metal comprising nano-crystal grains and a plurality of corrosion barrier layers in or between the nano-crystal grains throughout the body, the corrosion barrier layers comprising a metal nitride, a metal fluoride, or a combination thereof, wherein the metal is bioerodible.

3. The medical implant of claim 2, wherein the medical implant comprises a metal nitride of the metal.

4. The medical implant of claim 2, wherein the medical implant is an endoprosthesis.

5. The medical implant of claim 2, wherein the medical implant is stent.

6. The medical implant of claim 2, wherein the bioerodible metal comprises iron or an alloy thereof.

7. The medical implant of claim 2, wherein the bioerodible metal comprises magnesium or an alloy thereof.

8. A medical implant comprising a body that includes a metal comprising nano-crystal grains and a plurality of corrosion barrier layers in or between the nano-crystal grains throughout the body, the corrosion barrier layers comprising a metal nitride, a metal fluoride, or a combination thereof, wherein the medical implant comprises a metal nitride of the metal.

9. The medical implant of claim 8, wherein the medical implant is an endoprosthesis.

10. The medical implant of claim 8, wherein the medical implant is a stent.

11. The medical implant of claim 8, wherein the bioerodible metal comprises iron or an alloy thereof.

12. The medical implant of claim 8, wherein the bioerodible metal comprises magnesium or an alloy thereof.