Method of bonding porous metal to metal substrates

• US 8,383,033 B2
• Filed: 10/08/2009
• Issued: 02/26/2013
• Est. Priority Date: 10/08/2009
• Status: Active Grant

• Current Assignee: Biomet Manufacturing, LLC (Zimmer Biomet Holdings, Inc.)
• Original Assignee: Biomet Manufacturing, LLC (Zimmer Biomet Holdings, Inc.)
• Inventors: Gupta, Gautam
• Primary Examiner(s): King, Roy
• Assistant Examiner(s): MAI, NGOCLAN THI
• Application Number:
  US12/575,998
• Publication Number:
  US 20110085929A1
• Time in Patent Office: 1,237 Days
• Field of Search: 419/8, 419/36
• US Class Current: 419/8
• CPC Class Codes: A61F 2/30767 Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
• CPC Class Codes: A61F 2/3094 Designing or manufacturing processes
• CPC Class Codes: A61F 2/34 Acetabular cups
• CPC Class Codes: A61F 2002/30769 madreporic
• CPC Class Codes: A61F 2002/3092 having an open-celled or open-pored structure
• CPC Class Codes: A61F 2002/30929 having at least two superposed coatings
• CPC Class Codes: A61F 2002/30967 Diffusion bonding
• CPC Class Codes: A61F 2002/30968 Sintering
• CPC Class Codes: A61L 27/04 Metals or alloys
• CPC Class Codes: A61L 27/56 Porous materials, e.g. foams or sponges
• CPC Class Codes: B22F 3/1134 Inorganic fillers carbonaceous or paper filler B22F3/1121
• CPC Class Codes: B22F 7/004 comprising at least one non-porous part
• CPC Class Codes: Y10T 428/12042 Porous component
• CPC Class Codes: Y10T 428/12076 Next to each other

Abstract

A method for preparing an implant having a porous metal component. A loose powder mixture including a biocompatible metal powder and a spacing agent is prepared and compressed onto a metal base. After being compressed, the spacing agent is removed, thereby forming a compact including a porous metal structure pressed on the metal base. The compact is sintered, forming a subassembly, which is aligned with a metal substrate portion of an implant. A metallurgical bonding process, such as diffusion bonding, is performed at the interface of the subassembly and the metal substrate to form an implant having a porous metal component.

Claims

1. A method for preparing an implant having a porous metal component, comprising:

a. preparing a loose powder mixture comprising a biocompatible metal powder and a spacing agent;

b. compressing the powder mixture onto a metal base, the metal base comprising a solid metal layer of material taken from a solid metal block;

c. removing the spacing agent to form a compact having a porous metal structure pressed on the metal base;

d. sintering adjacent powder particles of the porous metal structure to one another while concurrently sintering the porous structure to the metal base to form a subassembly;

e. aligning the subassembly with a metal substrate component; and

f. forming a metallurgical bond by diffusion bonding the metal base of the subassembly and the metal substrate component to form an implant.

2. The method of claim 1, wherein the metal base comprises a metal backing surface, the metal substrate component comprises a metal face, and the diffusion bonding occurs at an interface between the metal backing surface and the metal face.

3. The method of claim 1, wherein the biocompatible metal powder is selected from the group consisting of titanium, titanium alloys, cobalt, cobalt alloys, chromium, chromium alloys, tantalum, tantalum alloys, iron alloys, stainless steel, and mixtures thereof.

4. The method of claim 1, wherein the spacing agent comprises ammonium bicarbonate and removing the spacing agent comprises heating the powder mixture.

5. The method of claim 1, wherein compressing the powder mixture onto the metal base comprises applying an isostatic pressing technique at ambient temperature.

6. The method of claim 1, wherein the porous metal structure and the metal base have the same chemical composition.

7. The method of claim 1, further comprising machining one or both of the porous metal structure and the metal substrate, prior to forming the metallurgical bond between the subassembly and the metal substrate.

8. The method of claim 1, further comprising machining one or both of the porous metal structure and the metal substrate, after forming the metallurgical bond between the subassembly and the metal substrate.

9. The method of claim 1, further comprising coating at least a surface of the porous metal implant with material selected from the group consisting of resorbable ceramics, resorbable polymers, antimicrobials, demineralized bone, blood products, stem cells, growth factors, and mixtures thereof.

17. The method of claim 1, wherein forming the metallurgical bond by diffusion bonding the metal base of the subassembly and the metal substrate component comprises maintaining a compressive force of between about 10 psi and about 30 psi along an interface between the metal base of the subassembly and the metal substrate component.

10. A method for preparing an implant having a porous metal component, comprising:

a. preparing a loose powder mixture comprising a biocompatible metal powder and a spacing agent;

b. compressing the powder mixture onto a solid metal base defining a metal surface;

c. heating the compressed powder mixture and defining a plurality of pores therein to form a compact;

e. sintering the compact to form a subassembly comprising a porous metal structure having a non-porous solid metal backing;

f. aligning the solid metal backing of the subassembly with a metal substrate component; and

g. diffusion bonding the solid metal backing to the metal substrate component to form an implant.

11. The method of claim 10, further comprising cooling the implant for a time period of from about 3 hours to about 20 hours in an inert atmosphere after the diffusion bonding.

12. The method of claim 10, wherein the diffusion bonding occurs along an interface between the non-porous solid metal backing and the metal substrate and comprises maintaining a compressive force of about 20 psi at the interface.

13. The method of claim 10, comprising providing the solid metal backing with a final thickness of about 0.5 mm.

14. A method for preparing an implant having a porous metal component, comprising:

a. placing a base layer comprising a biocompatible solid metal layer into a mold;

b. preparing a loose powder mixture of a biocompatible metal powder and a spacing agent;

c. forming a secondary layer by spreading the loose powder mixture in the mold on top of the base layer;

d. applying a compressive force to the mold thereby compressing the loose powder mixture of the secondary layer, and pressing the secondary layer onto the base layer;

e. removing the spacing agent, defining a plurality of pores within the secondary layer;

f. sintering the mold contents, including sintering adjacent powder particles of the secondary layer to one another while concurrently sintering the secondary layer to the base layer to form a subassembly including a porous metal structure having a solid metal backing; and

g. diffusion bonding the solid metal backing of the subassembly to a metal substrate component of an implant, forming an implant.

15. The method of claim 14, wherein the steps of removing the spacing agent and sintering the mold contents are carried out in a vacuum environment.

16. The method of claim 14, wherein diffusion bonding the solid metal backing of the subassembly to a metal substrate component of an implant comprises maintaining a compressive force of between about 10 psi and about 30 psi along an interface between the solid metal backing of the subassembly and the metal substrate component.