Antimicrobial medical devices containing chlorhexidine free base and salt
First Claim
Patent Images
1. An antimicrobial medical article prepared by treating a polymeric medical article, for an effective period of time, with a solution consisting essentially of one or more solvents and a mixture of chlorhexidine free base and a water-soluble chlorhexidine salt, wherein the weight/weight ratio of chlorhexidine free base and the water-soluble chlorhexidine salt in the solution is between 1:
- 1 to 1;
5.
0 Assignments
0 Petitions
Accused Products
Abstract
The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine salt in a weight/weight ratio of between about 1:1 to about 1:5, preferably about 1:1.
-
Citations
12 Claims
- 1. An antimicrobial medical article prepared by treating a polymeric medical article, for an effective period of time, with a solution consisting essentially of one or more solvents and a mixture of chlorhexidine free base and a water-soluble chlorhexidine salt, wherein the weight/weight ratio of chlorhexidine free base and the water-soluble chlorhexidine salt in the solution is between 1:
-
9. An antimicrobial medical article prepared by treating a polymeric medical article, for an effective period of time, with a solution consisting essentially of
(1) one or more solvents; -
(2) a mixture of chlorhexidine free base and a water-soluble chlorhexidine salt; and (3) one or more of (i) an organic acid, at a concentration of between 0.1 and 5percent;
(ii) an anti-inflammatory agent, at a concentration of between 0.1 and 5 percent;
or (iii) a hydrogel at a concentration of between 0.5 to 10 percent,wherein the weight/weight ratio of chlorhexidine free base and the water-soluble chlorhexidine salt in the solution is between 1;
1 to 1;
5. - View Dependent Claims (10, 11, 12)
-
Specification