Systems and methods for treatment of prostatic tissue

• US 8,388,611 B2
• Filed: 01/14/2010
• Issued: 03/05/2013
• Est. Priority Date: 01/14/2009
• Status: Active Grant

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: NxThera, Inc (Boston Scientific Corporation)
• Inventors: Shadduck, John H., Hoey, Michael
• Primary Examiner(s): Dvorak, Linda
• Assistant Examiner(s): Ram, Jocelyn D
• Application Number:
  US12/687,722
• Publication Number:
  US 20100179528A1
• Time in Patent Office: 1,146 Days
• Field of Search: 606/27, 606/41, 607/104, 607/105, 607/113, 604/113, 604/22, 604/500, 604/517
• US Class Current: 606/27
• CPC Class Codes: A61B 17/32002 with continuously rotating, oscillating or reciprocating cutting instruments
• CPC Class Codes: A61B 17/3203 Fluid jet cutting instruments
• CPC Class Codes: A61B 17/3205 Excision instruments
• CPC Class Codes: A61B 18/04 by heating by applying electromagnetic radiation A61B18/18; hyperthermia using electric or magnetic fields, radiation or ultrasound A61N
• CPC Class Codes: A61B 18/042 using additional gas becoming plasma
• CPC Class Codes: A61B 2017/00274 Prostate operation, e.g. prostatectomy, turp, bhp treatment
• CPC Class Codes: A61B 2018/00547 Prostate
• CPC Class Codes: A61B 2018/00577 Ablation
• CPC Class Codes: A61B 2018/048 in gaseous form
• CPC Class Codes: A61B 2090/376 using X-rays, e.g. fluoroscopy
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61B 2218/007 Aspiration

Abstract

A prostate therapy system is provided that may include any of a number of features. One feature of the prostate therapy system is that it can access a prostate lobe transurethrally. Another feature of the prostate therapy system is that it can deliver condensable vapor into the prostate to ablate the prostate tissue. Another feature of the prostate therapy system is that it can aspirate tissue from the prostate. Yet another feature of the prostate therapy system is that it includes a cutter that can rotate during delivery of vapor and aspiration of tissue. Methods associated with use of the prostate therapy system are also covered.

Claims

1. A method for treating a prostate disorder, comprising:

inserting a probe transurethrally into prostatic tissue;

rotating a cutter to volumetrically remove prostatic tissue in at least one lobe of the prostate, substantially without damage to the urethra; and

delivering a vapor from the probe to seal a margin of the removed prostatic tissue.

2. The method of claim 1 wherein the delivering step applies sufficient thermal energy to substantially modify tissue.

3. The method of claim 2 wherein the modification of tissue comprises weakening covalent bonds.

4. The method of claim 2 wherein the modification of tissue comprises denaturing proteins.

5. The method of claim 2 wherein the modification of tissue comprises disrupting collagen structures.

6. The method of claim 1 further comprising imaging the ablation probe.

7. The method of claim 1 wherein an applied energy from the vapor is between approximately 100 W and 1000 W.

8. The method of claim 1 wherein between approximately 10 grams and 50 grams of prostatic tissue are removed during the rotating step.

9. The method of claim 1 wherein an energy release from a phase change in the vapor seals the margin of the removed prostatic tissue.

10. A method for treating a prostate disorder, comprising:

introducing a tissue cutting instrument transurethrally into prostatic tissue;

actuating the tissue cutting instrument and a negative pressure source to cut and extract prostatic tissue; and

delivering a condensable vapor into the prostatic tissue.

11. The method of claim 10 wherein the delivering step applies sufficient thermal energy to substantially modify tissue.

12. The method of claim 11 wherein the modification of tissue comprises weakening covalent bonds.

13. The method of claim 11 wherein the modification of tissue comprises denaturing proteins.

14. The method of claim 11 wherein the modification of tissue comprises disrupting collagen structures.

15. The method of claim 10 wherein the delivering step applies sufficient thermal energy to seal or coagulate margins of the extracted prostatic tissue.

16. The method of claim 10 further comprising imaging the ablation probe.

17. The method of claim 10 wherein an applied energy from the vapor is between approximately 100 W and 1000 W.

18. The method of claim 10 wherein between approximately 10 grams and 50 grams of prostatic tissue are removed during the actuating step.

19. The method of claim 10 wherein an energy release from a phase change in the vapor seals the margin of the removed prostatic tissue during the delivering step.