Microfluidic chip frame

• US 8,394,341 B2
• Filed: 03/02/2005
• Issued: 03/12/2013
• Est. Priority Date: 03/08/2004
• Status: Active Grant

• Current Assignee: Agilent Technologies, Inc.
• Original Assignee: Agilent Technologies, Inc.
• Inventors: Reinhardt, Thomas, Baeuerle, Martin
• Primary Examiner(s): Bullock, In Suk
• Assistant Examiner(s): HYUN, PAUL SANG HWA
• Application Number:
  US11/070,811
• Publication Number:
  US 20050201902A1
• Time in Patent Office: 2,932 Days
• Field of Search: 422502-504, 422/508, 239/690
• US Class Current: 422/508
• CPC Class Codes: B01L 2200/025 Align devices or objects to ensure defined positions relative to each other
• CPC Class Codes: B01L 2200/08 Ergonomic or safety aspects of handling devices
• CPC Class Codes: B01L 2300/022 Transponder chips
• CPC Class Codes: B01L 2300/045 whereby the whole cover is slidable
• CPC Class Codes: B01L 2300/0816 Cards, e.g. flat sample carriers usually with flow in two horizontal directions
• CPC Class Codes: B01L 3/502715 characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
• CPC Class Codes: B01L 9/527 for microfluidic devices, e.g. used for lab-on-a-chip

Abstract

A frame for a microfluidic chip may be used together with a laboratory apparatus. The frame is adapted at least for one of the following features: receiving the microfluidic chip; protecting the microfluidic chip; and, positioning the microfluidic chip relative to the frame. The microfluidic chip is movable relative to the frame.

Claims

1. A miniaturized microfluidic device, comprising:

a microfluidic chip comprising;

an inlet port configured for connecting to a laboratory apparatus;

an outlet spray tip protected by a frame; and

a microfluidic channel connecting the inlet port and the outlet spray tip for analyzing or separating components of a liquid;

the frame receiving the microfluidic chip and configured to be used together with said laboratory apparatus, wherein said frame is further configured for permitting said microfluidic chip to be moveable relative to said frame.

2. The miniaturized microfluidic device of claim 1, wherein said frame is adapted for protecting said microfluidic chip.

3. The miniaturized microfluidic device of claim 1, wherein said frame comprises a first lock configured to interact with said microfluidic chip for keeping said microfluidic chip in a non-operating position.

4. The miniaturized microfluidic device of claim 3 wherein said first lock can be actuated by an opening mechanism to bring said microfluidic chip into an operating position of said microfluidic chip.

5. The miniaturized microfluidic device of claim 4, wherein said opening mechanism is an unlocking pin.

6. The miniaturized microfluidic device of claim 3, wherein said frame comprises a second lock to avoid separating said microfluidic chip and said frame.

7. The miniaturized microfluidic device of claim 1, wherein said microfluidic chip is removable from said frame.

8. The miniaturized microfluidic device of claim 1, wherein said frame includes a space frame comprising at least two layers.

9. The miniaturized microfluidic device of claim 8, wherein said space frame comprises a bottom layer, a middle layer, and a top layer, and wherein said middle layer of said space frame determines said space between said bottom layer and said top layer.

10. The miniaturized microfluidic device of claim 8, wherein at least one of said layers comprises a locking pawl configured to interact with a locking recess of said microfluidic chip, wherein said locking pawl and said locking recess are adapted for locking said microfluidic chip in a non-operating position of said microfluidic chip.

11. The miniaturized microfluidic device of claim 10, wherein a top layer comprises said locking pawl.

12. The miniaturized microfluidic device of claim 10, wherein said locking pawl is engaged with said recess of said microfluidic chip in said non-operating position of said microfluidic chip.

13. The miniaturized microfluidic device of claim 1, wherein said frame comprises a spring to move said microfluidic chip from an operating position to a non-operating position after use.

14. The miniaturized microfluidic device of claim 1, wherein said frame is fixed to an inside end of said microfluidic chip and said microfluidic chip further comprises a spring configured to move a distal end of said microfluidic chip automatically from an operating position back to a non-operating position after use.

15. The miniaturized microfluidic device of claim 14, wherein said spring is provided by a plurality of patterned recesses into a material of said microfluidic chip.

16. The miniaturized microfluidic device of claim 1, wherein said frame comprises a protection flap fixed by a hinge.

17. The miniaturized microfluidic device of claim 16, wherein said protection flap is hinged right-angled to a feeding direction of said frame inserted into said laboratory apparatus.

18. The miniaturized microfluidic device of claim 1, wherein said frame comprises a locking nose for locking said frame into said laboratory apparatus.

19. The miniaturized microfluidic device of claim 1, wherein said frame comprises a protection shield which is laterally movable in a feeding direction of said frame inserted into said laboratory apparatus.

20. The miniaturized microfluidic device of claim 1, wherein said microfluidic chip comprises a spring built of a plurality of patterned recesses in a material of said microfluidic chip.

21. The miniaturized microfluidic device of claim 1, wherein said frame comprises a window for accessing said microfluidic chip.

22. The miniaturized microfluidic device of claim 1, wherein said frame is adapted for positioning said microfluidic chip relative to said frame.

23. The miniaturized microfluidic device of claim 1, wherein said frame comprises an identification-tag.

24. The miniaturized microfluidic device of claim 1, wherein said frame comprises a catch to interact with a recess for keeping said microfluidic chip in a non-operating position.