Process, system and method for improving the determination of digestive effects upon an ingestable substance

• US 8,396,670 B2
• Filed: 08/16/2004
• Issued: 03/12/2013
• Est. Priority Date: 08/16/2004
• Status: Active Grant

• Current Assignee: Venture Lending
• Original Assignee: Venture Lending
• Inventors: St-Pierre, Normand
• Primary Examiner(s): SIMS, JASON M
• Application Number:
  US10/918,467
• Publication Number:
  US 20060036370A1
• Time in Patent Office: 3,130 Days
• Field of Search: None
• US Class Current: 702/19
• CPC Class Codes: A23K 10/24 from blood
• CPC Class Codes: A23K 50/10 for ruminants
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

The present invention generally relates to processes, computer programs and systems, methods of making such and methods of using such for improving the determination of one or more digestive effects upon an ingestable substance. The underlying data used in this determination may originate from either an in vitro or in vivo analysis. The processes may be either partially or fully manual or automated, and combinations thereof.

Claims

1. A process for correcting a directly measured (DM) undegraded percentage (U %) value of an ingestable substance (IS) within a feedstuff at an actual or simulated point along a digestive process in an organism, said process comprising the steps of:

i) obtaining a DM U % value of the IS in a sample specimen of the feedstuff;

ii) obtaining a DM U % value of the IS in a standard specimen of the feedstuff;

iii) looking up at least one stored prior U % value of the IS in respective prior standard specimens of the feedstuff;

iv) calculating a correction factor using Bayesian statistical analysis applied to the DM U % value of the IS in the standard specimen and the at least one stored prior U % value of the IS in the respective prior standard specimens;

v) multiplying the DM U % value of the IS in the sample specimen of the feedstuff by the correction factor to obtain a corrected DM U % value of the IS in the sample specimen of the feedstuff; and

vi) displaying the corrected DM U % value of the IS in the sample specimen of the feedstuff, wherein the steps are performed using a computer.

2. The process according to claim 1, wherein at least one value originates from the data of an in-vivo assay.

3. The process according to claim 1, wherein at least one value originates from the data of an in-vitro assay.

4. The process according to claim 1, wherein at least one value originates from the data of a single-step in-vitro assay.

5. The process according to claim 1, wherein at least one value originates from the data of a multi-step in-vitro assay.

6. The process according to claim 1, wherein at least one value originates from the data of an in-vitro assay modeling a normal digestive process.

7. The process according to claim 1, wherein at least one value originates from the data of an in-vitro assay modeling a digestive process associated with an extra-normal health condition.

8. A process according to claim 1, wherein at least one measurement is entered into a computer system.

9. A process according to claim 1, wherein at least one value is processed by a computer system.

10. A process according to claim 1, wherein the standard specimen comprises a substance that is less degradable when digestibility is compared with the sample specimen.

11. A process according to claim 1, wherein the standard specimen comprises blood meal and the substance is protein.

12. A process according to claim 1, wherein the standard specimen comprises a substance that is more degradable when digestibility is compared with the sample specimen.

13. A process according to claim 1, wherein the standard specimen comprises casein and the substance is protein.

14. A process according to claim 1, wherein said process further comprises modulating the protein content in the milk of a ruminant by feeding the ruminant a food mixture comprising a component that is the same as the sample.

15. A process according to claim 1, wherein said process further comprises modulating the protein production of a ruminant by feeding the ruminant a food mixture comprising a component that is the same as the sample.

16. A process according to claim 1, wherein said process further comprises modulating the body condition of a ruminant by feeding the ruminant a food mixture comprising a component that is the same as the sample specimen of the feedstuff.

17. A process according to claim 1, wherein said process further comprises modulating the overall feed intake or pasture usage by a ruminant by feeding the ruminant a food mixture comprising a component that is the same as the sample.

18. A process according to claim 1, wherein said process further comprises modulating the waste production by a ruminant by feeding the ruminant a food mixture comprising a component that is the same as the sample.

19. A process according to claim 1, wherein said process further comprises:

taking a measure of the U % of the IS in the sample specimen of the feedstuff.

20. The process of claim 1, wherein the correcting step comprises the steps of:

(ivA) correcting the DM U % value of the IS in the standard substance specimen using Bayesian statistical analysis applied to the DM U % value of the IS in the standard substance specimen and the at least one prior U % value of the IS in the respective prior standard substance specimens; and

(ivB) proportionally modifying the DM U % value of the sample specimen by the same proportion applied in correcting the DM U % value of the IS in the standard substance specimen.

21. The process of claim 1 further comprises the steps of:

ii) obtaining a DM U % value of the IS in a standard specimen of at least one other feedstuff; and

iii) looking up at least one stored prior U % value of the IS in respective prior standard specimens of the at least one other feedstuff;

wherein the correcting step corrects the DM U % value of the IS in the sample specimen using Bayesian statistical analysis applied to the DM U % value of the IS in the standard specimen, the at least one stored prior U % value of the IS in the respective prior standard specimens, the DM U % value of the IS in the at least one other standard specimen and the at least one stored prior U % value of the IS in respective at least one other prior standard specimen.

22. The process of claim 21, wherein the correcting step comprises the steps of:

(ivA) determining a correction factor using Bayesian statistical analysis applied to the DM U % value of the IS in the standard specimen, the at least one stored prior U % value of the IS in the respective prior standard specimens, the DM U % value of the IS in the at least one other standard specimen and the at least one stored prior U % value of the IS in respective at least one other prior standard specimen;

(ivB) multiplying the DM U % value of the IS in the sample specimen by the correction factor.