System and method of treating abnormal tissue in the human esophagus
First Claim
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1. A method of ablating mucosal tissue in an esophagus, comprising:
- positioning an ablation device at a desired site in the esophagus, the ablation device comprising a highly compliant balloon capable of expanding in the esophagus;
inflating the balloon to an appropriate pressure thereby extending at least a portion of the ablation device to a mucosal tissue surface at the site; and
ablating the tissue surface using the ablation device;
wherein the ablating causes necrosis to at least 75% of a mucosa layer and a submucosa layer and less than 25% of an underlying muscalaris layer.
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Abstract
An ablation catheter system and method of use is provided to endoscopically access portions of the human esophagus experiencing undesired growth of columnar epithelium. The ablation catheter system and method includes controlled depth of ablation features and use of either radio frequency spectrum, non-ionizing ultraviolet radiation, warm fluid or microwave radiation, which may also be accompanied by improved sensitizer agents.
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Citations
18 Claims
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1. A method of ablating mucosal tissue in an esophagus, comprising:
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positioning an ablation device at a desired site in the esophagus, the ablation device comprising a highly compliant balloon capable of expanding in the esophagus; inflating the balloon to an appropriate pressure thereby extending at least a portion of the ablation device to a mucosal tissue surface at the site; and ablating the tissue surface using the ablation device; wherein the ablating causes necrosis to at least 75% of a mucosa layer and a submucosa layer and less than 25% of an underlying muscalaris layer. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification