Methods of treating skin with aromatic skin-active ingredients

• US 8,399,521 B2
• Filed: 06/09/2010
• Issued: 03/19/2013
• Est. Priority Date: 02/01/2008
• Status: Active Grant

• Current Assignee: Mary Kay Incorporated (Mary Kay Holding Corporation)
• Original Assignee: Mary Kay Incorporated (Mary Kay Holding Corporation)
• Inventors: Walke, Bob, Florence, Tiffany C., Hines, Michelle D., Gomez, Cristie
• Primary Examiner(s): THOMAS, TIMOTHY P
• Application Number:
  US12/796,820
• Publication Number:
  US 20100249222A1
• Time in Patent Office: 1,014 Days
• Field of Search: None
• US Class Current: 514/690
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 2800/522 Antioxidants; Radical scavengers
• CPC Class Codes: A61K 31/045 Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
• CPC Class Codes: A61K 31/35 having six-membered rings with one oxygen as the only ring hetero atom
• CPC Class Codes: A61K 31/365 Lactones
• CPC Class Codes: A61K 8/33 containing oxygen
• CPC Class Codes: A61K 8/34 Alcohols
• CPC Class Codes: A61K 8/342 Alcohols having more than seven atoms in an unbroken chain
• CPC Class Codes: A61K 8/35 Ketones, e.g. benzophenone
• CPC Class Codes: A61K 8/37 Esters of carboxylic acids
• CPC Class Codes: A61K 8/4973 with oxygen as the only hetero atom
• CPC Class Codes: A61K 8/498 having 6-membered rings or their condensed derivatives, e.g. coumarin
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin

Abstract

A method for treating skin, reducing oxidative damage to a skin cell, reducing lipoxygenase (LO) activity in a skin cell, reducing cyclooxygenase (COX) activity in a skin cell, reducing tumor necrosis factor alpha (TNF-α) in a skin cell, or reduction matrix metalloproteinase enzyme activity in a skin cell comprising contacting skin or a skin cell with an aromatic skin-active ingredient.

Claims

1. A method of treating a fine line or wrinkle comprising topically applying to a fine line or wrinkle on skin a composition comprising 3-hexen-l-ol, 4-methyl-3-decen-5-ol, and (3E)-4-(2,6,6-trimethylcyclohex-l-en-l-yl)but-3-en-2- one, each applied in an amount effective to reduce MMP-9 activity in a skin cell of the skin, wherein the composition treats said fine line or wrinkle.

2. The method of claim 1, wherein the composition is an emulsion, a cream, or a lotion.