Multiple wavelength physiological measuring apparatus, sensor and interface unit for determination of blood parameters

• US 8,401,605 B2
• Filed: 04/30/2009
• Issued: 03/19/2013
• Est. Priority Date: 04/30/2009
• Status: Active Grant

• Current Assignee: General Electric Company
• Original Assignee: General Electric Company
• Inventors: Huiku, Matti
• Primary Examiner(s): Winakur, Eric
• Assistant Examiner(s): Liu, Chu Chuan (JJ)
• Application Number:
  US12/432,982
• Publication Number:
  US 20100280342A1
• Time in Patent Office: 1,419 Days
• Field of Search: 600/310, 600/322, 600/323, 600/324, 600/326, 600/331, 600/344, 600/473, 600/476
• US Class Current: 600/322
• CPC Class Codes: A61B 2560/045 with a separable interface unit, e.g. for communication
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor

Abstract

A measuring apparatus, a physiological sensor, and an interface unit for determining blood parameters of a subject are disclosed. The sensor comprises an emitter unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths and a detector unit configured to receive radiation generated by the emitter elements and transmitted through the tissue of the subject, wherein the detector unit is further configured to produce electric measurement signals indicative of absorption caused by the blood of the subject. The sensor or the interface unit is provided with a memory that stores emitter activation information for at least a third plurality of wavelengths, thereby to enable a monitoring unit operably connectable to the physiological sensor to employ a combination of wavelengths selected from the third plurality of wavelengths, wherein the third plurality is equal to or smaller than the second plurality.

Claims

1. A measuring apparatus for determining the amount of at least one substance in blood of a subject, the measuring apparatus comprising:

a sensor unit comprising

an emitter unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths; and

a detector unit configured to receive radiation generated by the emitter elements and transmitted through tissue of a subject, wherein the detector unit is further configured to produce electric measurement signals indicative of absorption caused by blood of the subject;

a first memory storing emitter activation information for at least a third plurality of wavelengths, wherein the third plurality of wavelengths belongs to the second plurality of wavelengths, and wherein the emitter activation information indicates, for each wavelength in the third plurality of wavelengths, input terminals of the sensor unit to which the corresponding emitter element is connected; and

a monitoring unit configured to process the electric measurement signals, wherein the monitoring unit is further configured to produce, based on the emitter activation information, control information for employing a desired combination of wavelengths selected from the third plurality of wavelengths.

2. The measuring apparatus according to claim 1, wherein the first memory is in the sensor unit.

3. The measuring apparatus according to claim 1, wherein the emitter activation information indicates, for each wavelength in the third plurality of wavelengths, a polarity of current to be supplied to said input terminals.

4. The measuring apparatus according to claim 1, wherein the emitter activation information comprises at least one control code, and wherein each control code is linked to the control information required to employ a particular combination of wavelengths.

5. The measuring apparatus according to claim 2, wherein the emitter unit comprises at most n+1 input terminals and the first plurality of emitter elements comprises 2n emitter elements.

6. The measuring apparatus according to claim 1, further comprising an interface unit operably connected between the sensor unit and the monitoring unit.

7. The measuring apparatus according to claim 6, wherein the first memory is in the interface unit.

8. The measuring apparatus according to claim 6, wherein the monitoring unit comprises a single drive current source operably connectable to an emitter switching unit in the interface unit.

9. The measuring apparatus according to claim 1, wherein the monitoring unit is further configured to change the desired combination of wavelengths in time domain.

10. The measuring apparatus according to claim 1, wherein the monitoring unit is further configured to pre-check compatibility of the sensor unit with any combination of wavelengths intended to be employed in the measuring apparatus.

11. A physiological sensor for use in determining the amount of at least one substance in blood of a subject, the physiological sensor being attachable to the subject and comprising:

an emitter unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths;

a sensor memory storing emitter activation information for at least a third plurality of wavelengths, thereby to enable a monitoring unit operably connectable to the physiological sensor to employ a desired combination of wavelengths selected from the third plurality of wavelengths, wherein the third plurality of wavelengths belongs to the second plurality of wavelengths, and wherein the emitter activation information indicates, for each wavelength in the third plurality of wavelengths, input terminals of the sensor corresponding to which the required emitter element is connected; and

a detector unit configured to receive radiation generated by the emitter elements and transmitted through tissue of the subject, wherein the detector unit is further configured to produce electric measurement signals indicative of absorption caused by blood of the subject.

12. The sensor according to claim 11, wherein the emitter activation information indicates, for each wavelength in the third plurality of wavelengths, a polarity of current to be supplied to said input terminals.

13. The sensor according to claim 12, wherein the emitter activation information comprises an extinction matrix including extinction coefficients for a plurality of blood substances.

14. The sensor according to claim 11, wherein the emitter activation information comprises at least one control code, and wherein each control code is linked to the control information required to employ a particular combination of wavelengths belonging to the third plurality of wavelengths.

15. The sensor according to claim 11, wherein the first plurality of emitter elements comprises 2n emitter elements and the emitter unit comprises at most n+1 input terminals.

16. The sensor according to claim 11, wherein the sensor memory stores the emitter activation information for the third plurality of wavelengths and wherein the third plurality of wavelengths equals to the second plurality of wavelengths.

17. The sensor according to claim 16, wherein the first plurality of emitter elements is greater than the second plurality of wavelengths.

18. A sensor arrangement for use in determining the amount of at least one substance in blood of a subject, the sensor arrangement comprising:

a sensor unit comprising a first plurality of emitter elements configured to emit radiation at a second plurality of wavelengths; and

an interface unit comprising;

a first interface for connecting the interface unit to a monitoring unit;

a second interface connected to the sensor unit;

an emitter switching unit configured to connect drive current generated by the monitoring unit to the sensor unit through the second interface; and

a memory storing emitter activation information for at least a third plurality of emitter elements, thereby to enable the monitoring unit to employ a desired combination of wavelengths selected from the third plurality of wavelengths, and wherein the emitter activation information indicates, for each wavelength in the third plurality of wavelengths, input terminals of the sensor unit to which the corresponding emitter element is connected, wherein the third plurality of wavelengths belongs to the second plurality of wavelengths.

19. The interface unit according to claim 18, wherein the emitter activation information comprises at least one control code, and wherein each control code is linked to the control information required to employ a particular combination of wavelengths selected from the third plurality of wavelengths.

20. The interface unit according to claim 19, wherein the at least one control code comprises a plurality of control codes for multiple monitoring units with different measuring capabilities.